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What are the main uses of 4-Amino-3-iodo-1H-pyrazolo [3,4-D] pyridine?
4-Amino-3-iodine-1H-pyrazolo [3,4-d] pyridine is one of the organic compounds. Its main uses are quite extensive, and it is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its unique chemical structure, it has the potential to interact with specific targets in organisms, so it can be modified and modified to develop drugs with specific pharmacological activities, such as anti-tumor, anti-virus and other drugs.
In the field of materials science, such compounds may contribute to the preparation of special functional materials. Due to its specific electronic properties and chemical stability, it can be applied to the field of optoelectronic materials, participating in the construction of organic Light Emitting Diode (OLED) or solar cells, and contributing to the improvement of the properties of materials.
Furthermore, in chemical research, it is also an important research object. Chemists can use in-depth investigation of its reaction characteristics to expand the methods and strategies of organic synthesis, improve the understanding of the reaction mechanism of nitrogen-containing heterocyclic compounds, and then promote the development of organic chemistry. Therefore, 4-amino-3-iodine-1H-pyrazolo [3,4-d] pyridine is indispensable and important in many fields such as medicine, materials and chemical research.
What are the synthesis methods of 4-Amino-3-iodo-1H-pyrazolo [3,4-D] pyridine
The synthesis of 4-amino-3-iodine-1H-pyrazolo [3,4-d] pyridine is rather complicated and requires fine steps and appropriate reagents.
One method may be initiated from pyrazolo [3,4-d] pyridine. First, the amino group is introduced at a specific position on the pyridine ring with a suitable amination reagent. This process requires attention to the precise regulation of reaction conditions, such as temperature, pH, etc., to ensure that the amination reaction can occur smoothly at the desired check point.
Then, the iodization reaction is carried out. An iodine source and a suitable catalyst can be selected to react with aminylated pyrazolo [3,4-d] pyridine to introduce iodine atoms into the target site. During iodization, careful control of reaction parameters is also required to prevent the growth of side reactions, such as excessive iodization or other unexpected reactions.
Another approach may be to construct the basic structure of pyrazolo [3,4-d] pyridine first, and then gradually introduce amino and iodine atoms. For example, a specific cyclization reaction can be used to build the skeleton of pyrazolo-pyridine, and then the aminylation and iodization steps can be carried out in sequence. After each step of the reaction, purification methods such as column chromatography and recrystallization are required to obtain a purified product.
During the synthesis process, it is crucial to confirm the structure of the intermediate and the final product. The correctness of the product can be verified by nuclear magnetic resonance, mass spectrometry, infrared spectroscopy and other analytical methods. And each step of the reaction needs to be carefully monitored, and the conditions should be adjusted according to the reaction process to achieve the ideal yield and purity. In this way, the target product 4-amino-3-iodine-1H-pyrazolo [3,4-d] pyridine can be obtained.
What are the physical properties of 4-Amino-3-iodo-1H-pyrazolo [3,4-D] pyridine
4-Amino-3-iodine-1H-pyrazolo [3,4-d] pyridine has many physical properties. Its appearance is often white to light yellow powder, which is conducive to observation and preliminary resolution.
When it comes to solubility, it shows certain characteristics in common organic solvents. In dimethyl sulfoxide (DMSO), it has a good solubility and can be uniformly dispersed to form a clear solution. However, in polar solvents such as water, the solubility is poor, only slightly soluble or insoluble, which is related to its molecular structure and polarity.
In terms of melting point, after accurate determination, it is about a certain temperature range. This melting point value is an important physical sign of the substance and can be used for purity identification. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point may decrease and the melting range becomes wider.
Its density is also a key physical property, and specific values can be obtained by professional means. Density reflects the mass of a substance per unit volume. When applied in the fields of chemical industry and materials, this data is of great significance for calculating dosage and designing processes.
In addition, the stability of the substance cannot be ignored. In a normal temperature and pressure, dry environment, it is relatively stable and can maintain its own chemical structure and properties. However, in case of specific chemical reagents such as strong oxidizing agents, strong acids and bases, or extreme conditions of high temperature and humidity, chemical reactions may occur, resulting in changes in structure and properties.
The physical properties described above are all important factors to consider in the process of research, production and application of 4-amino-3-iodine-1H-pyrazolo [3,4-d] pyridine, which helps to better understand its characteristics and behavior.
What is the price of 4-Amino-3-iodo-1H-pyrazolo [3,4-D] pyridine in the market?
I have not obtained the exact price of 4 - Amino - 3 - iodo - 1H - pyrazolo [3,4 - D] pyridine in the market. The price of this product may vary greatly due to various factors such as purity, supply, and purchase volume.
If it is normal, in the fine chemical market, the price of high-purity special organic compounds is often expensive. This compound has a unique chemical structure, and the synthesis may require complicated steps and special raw materials, or the cost may be high.
If it is purchased in small quantities for scientific research purposes, and the purity is more than 95%, the price per gram may be hundreds or even thousands of yuan. However, if it is an industrial-scale purchase, the unit price may decrease slightly due to the large purchase volume.
To know the exact market price, you should consult professional chemical product suppliers, chemical reagent distributors, or check chemical product trading platforms to obtain accurate price information.
What are the storage conditions for 4-Amino-3-iodo-1H-pyrazolo [3,4-D] pyridine?
4-Amino-3-iodine-1H-pyrazolo [3,4-d] pyridine, this is an organic compound. The method of storage is related to its properties and is extremely important.
Looking at its structure, it contains amino groups, iodine atoms and pyrazolopyridine heterocycles. Amino groups have certain basicity, iodine atoms can cause molecular polarity differences, and pyrazolopyridine heterocycles add to the complexity of their chemical activities.
Because of the active groups, this compound should be stored in a cool, dry and well-ventilated place. Avoid direct sunlight to prevent light from initiating decomposition or reaction. Sunlight energy or chemical bond breaking, causing it to deteriorate. < Br >
And because it may be sensitive to air, if conditions permit, it is suitable for inert gas environments, such as nitrogen atmosphere. Oxygen, water vapor, etc. in the air may react with compounds, damaging their purity and stability.
Furthermore, this compound may be hygroscopic, so it should be sealed and stored. Desiccant can also be used to remove water vapor in the environment, prevent it from being hydrolyzed by moisture, and maintain its chemical structure integrity.
When using, it is also necessary to be careful and operate according to specifications to prevent impurities from being mixed in and ensure its quality. In this way, the stability of 4-amino-3-iodine-1H-pyrazolo [3,4-d] pyridine can be preserved for scientific research and production.