4 Amino 2 Methoxypyridine
pyridine pyrrole pyrazine piperidine piperazine

4-Amino-2-methoxypyridine

    Specifications

    HS Code

    166729

    Chemical Formula C6H8N2O
    Molar Mass 124.14 g/mol
    Appearance Solid (usually white or off - white)
    Odor Typically has a mild, amine - like odor
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in polar organic solvents like ethanol, methanol, acetone
    Melting Point 97 - 101 °C
    Boiling Point 267 - 269 °C
    Pka For the amino group, pKa is around 9 - 10 (approximate value for amino - pyridine derivatives)

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    General Information
    Where to Buy 4-Amino-2-methoxypyridine in China?
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    Frequently Asked Questions

    As a leading 4-Amino-2-methoxypyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-Amino-2-methoxypyridine?
    4-Amino-2-methoxypyridine is a class of organic compounds. It has a wide range of uses and is often a key intermediate in the synthesis of many drugs in the field of medicinal chemistry. Due to its specific chemical structure, it can interact with specific targets in organisms and help build molecular structures with specific pharmacological activities.
    In the field of pesticide chemistry, it also has significant functions. It can be used as an important raw material for the synthesis of new pesticides. With its unique chemical properties, pesticides are given better insecticidal, bactericidal or herbicidal properties, and the impact on the environment is relatively small, which is in line with the needs of the current development of green agriculture.
    In addition, in the field of materials science, 4-amino-2-methoxypyridine has also emerged. It can be used to prepare organic materials with specific functions, such as materials with special photoelectric properties, used in organic Light Emitting Diodes, solar cells and other fields, which contribute to the progress of materials science. Because it can be combined with other molecules through chemical modification to regulate the physical and chemical properties of materials, so as to meet the requirements of different application scenarios. In conclusion, 4-amino-2-methoxypyridine, with its unique chemical structure, plays an indispensable role in many fields such as medicine, pesticides, and materials science, and promotes technological innovation and development in various fields.
    What are 4-Amino-2-methoxypyridine synthesis methods?
    4-Amino-2-methoxypyridine is an important compound in organic synthesis. The synthesis method has been explored by chemists in the past, and the methods are various. Today, I will choose the main one to describe.
    One method is to use 2-methoxypyridine as the starting material. First, 2-methoxypyridine and an appropriate nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, can be used under suitable temperature and reaction conditions to obtain 2-methoxy-4-nitropyridine. In this step, attention should be paid to the control of temperature. If it is too high, the side reactions will increase, and if it is too low, the reaction rate will be slow. Next, the obtained 2-methoxy-4-nitropyridine is treated with a reducing agent, which is commonly used as a system of iron powder and hydrochloric acid, or hydrogen is reduced in the presence of a catalyst such as palladium carbon to convert the nitro group into an amino group, and then 4-amino-2-methoxy pyridine is obtained.
    The second method uses 2-chloro-4-nitropyridine as the starting material. First react with sodium methoxide to replace the chlorine atom with methoxy to obtain 2-methoxy-4-nitropyridine, and then go through the reduction step, as described in the previous method, by iron powder-hydrochloric acid or catalytic hydrogenation, the nitro group is reduced to an amino group, and the target product can also be obtained.
    There are also pyridine derivatives as starting materials. After multiple steps of reaction, such as halogenation, substitution, reduction, etc., the reaction route is cleverly designed, and the purpose of synthesizing 4-amino-2-methoxy pyridine can also be achieved. Each method of synthesis has its own advantages and disadvantages, and it is necessary to choose carefully according to actual needs, considering factors such as the availability of raw materials, the difficulty of reaction, and the high cost.
    What are the physical properties of 4-Amino-2-methoxypyridine?
    4-Amino-2-methoxypyridine is one of the organic compounds. It has many physical properties, which are described as follows:
    1. ** Properties **: Under normal conditions, 4-amino-2-methoxypyridine is a white to light yellow crystalline powder. This appearance characteristic is very important for the identification and preliminary identification of this substance. Looking at its color and state, it can be preliminarily determined whether it is this compound.
    2. ** Melting point **: Melting point is between 104-106 ° C. Melting point is an important physical constant of the substance, which can assist in determining the purity of the substance. If the measured melting point is consistent with the standard value, and the melting range is narrow, it indicates that the purity of the substance is high; if the melting point is deviated or the melting range is widened, it is very likely to contain impurities.
    3. ** Solubility **: This compound is slightly soluble in water, but it can be soluble in organic solvents such as methanol, ethanol, and chloroform. The solubility characteristics are closely related to its molecular structure, and the amino group and methoxy group in the molecule affect its interaction with different solvents. Slightly soluble in water, because water is a strong polar solvent, and the polarity of the compound is relatively weak; soluble in the above organic solvents, because these solvents and 4-amino-2-methoxy pyridine molecules can form interactions such as hydrogen bonds, van der Waals forces, etc., and then dissolve it.
    4. ** Odor **: Generally speaking, it has a weak special odor. Although odor is sensory, it can also assist in identification in some situations. A specific odor may suggest the existence of such compounds, but the smell alone is not enough to accurately determine, and it needs to be considered in combination with other properties.
    5. ** Stability **: Under normal storage and use conditions, 4-amino-2-methoxypyridine is relatively stable. However, it needs to be avoided from contact with strong oxidants, strong acids, strong bases and other substances, because it may chemically react with it, resulting in structural changes and property changes. When storing, it should be placed in a cool, dry, well-ventilated place away from incompatible substances to ensure its stability and quality.
    What is the price range of 4-Amino-2-methoxypyridine in the market?
    4-Amino-2-methoxypyridine is in the market, and its price range is difficult to determine. The price of this substance often changes for various reasons. Such as the source of the material, if the material is plentiful and easy to obtain, the price may be slightly flat; on the contrary, if the material is thin and difficult to obtain, the price will be high. And the craftsmanship is clumsy, those who are good at making it, save industry and produce more, and their price may be cheap; those who are dull in craftsmanship, are complex and produce less, and the price will be high. There are ups and downs in the market, and those who ask for it will increase the price; those who ask for it will reduce the price.
    In the past, in the market of chemical materials, the price of such fine products varies from time to time. If there is a quantity, the price per gram, or between a few gold and tens of gold. If you buy in bulk, the price varies depending on the quantity. Approximately a small amount of purchase, the price is often slightly higher; if the quantity is large, you can negotiate with the merchant to get a better price.
    However, this is only an approximate number. The current price must be carefully considered in the current market conditions and the pricing of the merchant before it can be determined. To know the details, you should ask the merchant of chemical materials or observe the professional trading platform to clarify the actual price.
    What are 4-Amino-2-methoxypyridine storage conditions?
    4-Amino-2-methoxypyridine is an organic compound, which is widely used in chemical industry, medicine and other fields. Its storage conditions are extremely critical, which is related to material stability and quality.
    This compound should be stored in a cool and ventilated warehouse. Due to high temperature, it is easy to cause chemical reactions, or cause decomposition and deterioration, so it is necessary to avoid high temperature environment. The temperature of the warehouse should not exceed 30 ° C.
    At the same time, keep the warehouse dry. 4-Amino-2-methoxypyridine has certain hygroscopicity, and its purity and properties may be affected after moisture. The humidity should be controlled at a relative humidity of not more than 75%.
    In addition, when storing, it must be stored separately from oxidants, acids, etc. These substances come into contact with them, or cause violent chemical reactions, resulting in fire, explosion and other hazards.
    In addition, the storage place should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. In case of unexpected situations such as leaks, timely response measures can be taken to reduce hazards.
    When handling, light handling is required to prevent damage to packaging and containers. If the packaging is damaged, it will not only affect the substance itself, but also cause pollution to the surrounding environment. In conclusion, 4-amino-2-methoxypyridine should be stored in a cool, dry place, away from incompatible substances, and prepared for emergencies to ensure its safe storage and stable quality.