4-Amino-2-chloropyridine

4-Amino-2-chloropyridine is also an organic compound. It has a wide range of uses and has important applications in many fields.
In the field of medicinal chemistry, this compound is a key intermediate. Due to its unique chemical structure, it can participate in a variety of drug synthesis reactions. The development and preparation of many drugs often rely on it as the starting material or the reactant of the key step. Through a series of chemical reactions, it can be converted into drug molecules with specific pharmacological activities, such as antibacterial drugs, antiviral drugs, etc., to provide help for human beings to fight diseases.
In the field of pesticides, 4-amino-2-chloropyridine also plays an important role. It can be used as an important component of synthetic pesticides to prepare insecticides, fungicides, etc. Because of its structure, pesticides can be endowed with specific biological activities, making them effective in killing pests, inhibiting the growth of pathogens, ensuring the healthy growth of crops, and increasing food yield.
Furthermore, in the field of materials science, it can also be seen. It can participate in the synthesis of some functional materials, endowing materials with special physical or chemical properties, such as improving the stability and conductivity of materials, thereby expanding the application range of materials.
In short, 4-amino-2-chloropyridine has shown important uses in many fields such as medicine, pesticides, and materials due to its unique chemical properties, and plays an important role in the development of related industries.

4-Amino-2-chloropyridine is one of the organic compounds. It has many physical properties and is hereby referred to as Jun Chen.
First of all, its appearance is often white to light yellow crystalline powder. This state is easy to observe and distinguish, and is a key characterization for preliminary identification in various experiments and industrial processes.
As for the melting point, it is about 146-150 ° C. The exact value of the melting point is like a unique imprint of a substance, which helps chemists to precisely control the temperature conditions when identifying and purifying this substance. To obtain pure 4-amino-2-chloropyridine, the determination of the melting point is an indispensable step. < Br >
Solubility is also an important physical property. It exhibits a certain solubility in organic solvents such as methanol, ethanol, dichloromethane, etc. In methanol, the degree of solubility varies with the rise and fall of temperature. This solubility gives it a unique advantage in organic synthesis. Chemists can choose a suitable solvent according to its characteristics to make the reaction proceed smoothly, or to achieve effective separation and purification of the product.
Furthermore, this material has a certain stability. It can exist relatively stably in a dry environment at room temperature and pressure. However, in case of high temperature, strong oxidant or specific acid-base conditions, its chemical structure may change. This knowledge of stability is essential when storing and transporting 4-amino-2-chloropyridine. Specific specifications must be followed to ensure its quality and safety.
In addition, although its odor is not strongly pungent, it also has a unique smell. When handling this substance, this odor can provide the experimenter with an initial warning of the existence of this substance, so that they can take appropriate protective measures.
In summary, the physical properties of 4-amino-2-chloropyridine, such as appearance, melting point, solubility, stability and odor, are of great significance in the research of organic chemistry, industrial production and related application fields, to help researchers and producers make good use of this substance and avoid risks.

4-Amino-2-chloropyridine is also an organic compound. The method of its synthesis has been studied in the past. One of the common methods is to use 2-chloropyridine as the starting material, and first go through the nitrification step to introduce nitro groups into the pyridine ring. This step requires appropriate temperature and adaptability to control the direction of the reaction. A mixed acid of nitric acid and sulfuric acid is commonly used, and the nitro group is inserted into the appropriate position of the pyridine ring.
Then, the obtained nitro compound is treated with a suitable reducing agent to convert the nitro group into an amino group. For example, when using iron powder, hydrochloric acid system, or strong reducing agent such as lithium aluminum hydride, the operation should be careful because of its high activity. After this step of reduction, 4-amino-2-chloropyridine can be obtained.
There is another method, which is obtained by cyclization of raw materials containing amino groups and chlorine atoms. For example, an amine and a halogenated hydrocarbon with appropriate substituents are selected. Under the catalysis of a base, the intermediate product is first formed, and then the pyridine ring is formed by intramolecular cyclization, and then the target product is obtained. In this process, the type and dosage of the base, the temperature and time of the reaction need to be finely regulated to obtain a higher yield.
Furthermore, amino groups and chlorine atoms can be introduced through selective substitution reactions starting from pyridine derivatives. Therefore, it is necessary to make good use of the electron cloud distribution characteristics of the pyridine ring, select suitable reagents and conditions, and make the substitution reaction precisely occur at the desired position to form 4-amino-2-chloropyridine.

The price range of 4-amino-2-chloropyridine in the market is difficult to determine. The price of this chemical often changes for various reasons.
First, the amount of quantity has a great impact on the price. If you want to buy a large quantity, the supplier may give a preferential price because of the thick profit; if the quantity is small, the price may be slightly higher.
Second, the quality is also the main reason. The high purity of 4-amino-2-chloropyridine is difficult to prepare and the process is complicated, so the price is often higher than that of ordinary purity. However, in some places where it is not used harshly, ordinary purity is sufficient, and the price is also suitable.
Third, the supply and demand of the city is dominated by the price. If the demand is prosperous and the supply is limited, the price will rise; if the supply exceeds the demand, the price may fall.
Fourth, the source and the transportation route are also involved in the price. For local producers, because there are no fees and taxes for long-distance transportation, the price may be low; for those who come from abroad, the price may increase due to the addition of freight, customs duties, etc.
According to past market conditions, the price of 4-amino-2-chloropyridine per kilogram may be as low as hundreds of yuan, and as high as thousands of yuan. However, this is only a rough estimate. To obtain an accurate price, you need to consult the supplier in detail and compare their quotations to know the exact price range at the moment.

4-Amino-2-chloropyridine is an important chemical substance. Its storage conditions are related to its quality and stability, and must not be ignored.
If you want to store this substance well, you should first choose a cool and dry place. Cover 4-amino-2-chloropyridine is resistant to heat and humidity. If it is in a warm and humid environment, it is afraid of deterioration. Warm heat can easily accelerate its chemical reaction, and dampness may cause adverse changes such as hydrolysis. Therefore, it can be placed in a cool and dry place to slow down its deterioration and maintain its inherent nature.
Furthermore, it must be sealed and stored. This is due to the exposure of 4-amino-2-chloropyridine to the air, which is easy to contact with oxygen, water vapor and other impurities, resulting in damage to the quality. The sealing device can prevent external interference and stabilize its composition. It is appropriate to use a sealed container made of glass or specific plastic materials. These materials are chemically stable and not easy to react with 4-amino-2-chloropyridine, which can protect its integrity for a long time.
And the storage place should be kept away from fire and heat sources. 4-amino-2-chloropyridine may be flammable, in case of open flame, hot topic, or risk of combustion and explosion. Therefore, in the storage place, when fireworks are strictly prohibited, properly manage the heat source to prevent accidents.
In addition, ventilation of the storage environment is also key. Good ventilation can disperse possible escaping gases to prevent their accumulation from causing excessive concentration and causing safety hazards. And ventilation helps to maintain the dryness of the environment, which is of great benefit to the storage of 4-amino-2-chloropyridine.
It should be stored separately from oxidants, acids and other substances. 4-amino-2-chloropyridine is chemically active, coexists with oxidants and acids, or reacts violently, endangering safety. Therefore, it can be stored in categories to avoid the harm of interaction.
In general, the storage of 4-amino-2-chloropyridine needs to be cool, dry, sealed, away from fire heat sources, ventilated, and classified to ensure its quality and safety.