4,6-Dichloropyridine-3-carboxylic acid

4,6-Dinitro-m-benzene-3-carboxylic acid, although this substance is not detailed in "Tiangong Kaiwu", it has a wide range of uses according to today's knowledge.
First, in the field of medicine, it may be used as a raw material to make special drugs. As the ancient saying goes, "Medicine is benevolent, and medicine is the rescue of disease". This compound has been cleverly processed, and it may become a good medicine for the world, relieving the pain of the sick. Second, in the dye industry, it may have a unique color and stability, and can be used to make gorgeous dyes. The ancients also attached importance to the beauty of clothing, "clothing with a seal body", and the dyes made from this material dyed the fabric or colorful, which is everlasting. Third, in agriculture, it may be used to develop pesticides, protect crops, and ensure the abundance of grains. The ancient farmers, "plow in spring and summer, harvest in autumn and store in winter", if this material is used to make good medicine, remove insects and protect seedlings, the field will be free of wasteland and filth, and the warehouse will be enriched. Fourth, in scientific research and exploration, as a key intermediate, it helps chemists to open up unknown fields, "take things to know", and promote the progress of chemistry by understanding the properties and changes of substances.

To prepare 4,6-dinitroisophthalic acid-3-formonitrile, there are various methods. First, isophthalic acid is used as the beginning, and it is obtained by nitrification and formonitrification. First, the isophthalic acid is placed in a mixed acid of sulfuric acid and fuming nitric acid, and the temperature control reaction is carried out to nitrate the benzene ring to obtain 4,6-dinitroisophthalic acid. Next, the product is reacted with thionyl chloride to form an acid chloride, and then interacts with sodium cyanide or other cyanide reagents to introduce a formonitrile group, and then the target product is obtained.
Second, isophthalonitrile is used as the starting material. First, isophthalonitrile is reacted with mixed acid. After nitrification, a nitro group is introduced at a specific position in the benzene ring to generate 4,6-dinitro isophthalonitrile. Then, it is partially hydrolyzed to convert one of the nitrile groups into carboxyl groups, resulting in 4,6-dinitro isophthalic acid-3-formonitrile.
Third, starting from m-toluic acid. First, p-toluic acid is nitrified to obtain 4,6-dinitro-m-toluic acid. Then the methyl is oxidized to a carboxyl group, and the carboxyl group is converted into a formonitrile group through a re-formitrification reaction, thereby obtaining 4,6-dinitro-m-phthalic acid-3-formonitrile. Each method has its own advantages and disadvantages, depending on the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.

Today, there are 4,2,6-dinitrotoluene-3-carboxylic acid. What is the market median price? This is a chemical product, and its price often varies due to changes in time, land, quality and supply and demand.
In the normal situation of market change, its price is related to multiple reasons. First, the price of raw materials. If the price of raw materials for this product rises, the price of finished products will also rise; the price of raw materials is reduced, and the price of finished products may fall. Second, the situation of supply and demand. If there are many applicants and there are few suppliers, the price will increase; if the supply exceeds the demand, the price will decrease. Third, the difficulty of preparation. If the preparation method is difficult, it requires exquisite craftsmanship and high cost, and the price is not low; if the preparation is easy, the price may be slightly cheaper.
Looking at today, it is difficult to determine the price because there is no exact supply and demand at the time. However, it is common to observe the chemical market, and the price often fluctuates between tens of yuan and hundreds of yuan per kilogram. Or because of the high quality and difficulty in preparation, the price can reach hundreds of yuan per kilogram; if the quality is average, the preparation is easy and the supply is sufficient, the price may only be a few tens of yuan per kilogram. For details, when you look at the chemical trading platform and ask people in the industry, you may get a near-real price.

4,6-Dinitroresorcinol-3-sulfonic acid is an important chemical, and its Quality Standard is very critical.
This compound is widely used in industrial production and many fields, and the Quality Standard is related to its performance and use. In terms of purity, it needs to reach a very high level, and the impurity content must be strictly controlled. Due to impurities or affecting its chemical reactivity, the reaction results are deviated, which affects the quality of the product.
Appearance is also an important standard, and it should be of a specific color and morphology, which is convenient for identification and quality initial judgment. For example, the appearance color is abnormal, or it indicates that there is a problem in the production process, or impurities are mixed.
Relevant physical and chemical properties indicators are also critical, such as melting point, boiling point, solubility, etc., accurately determined and meet the standards to ensure stable performance in different environments and application scenarios. Melting point does not match, or indicates that the crystal structure is different, affecting the use.
For harmful impurities limit, must be strictly set and tested. Harmful impurities or threaten production safety, or cause harm to the environment and human health. Strict control of harmful impurities can reduce latent risk.
In practical applications, such as as as an intermediate for the synthesis of other compounds, whether the Quality Standard is qualified or not directly determines the quality and performance of the final product. Therefore, the production and testing process should strictly follow the Quality Standards to ensure the stable and reliable quality of 4,6-dinitroresorcinol-3-sulfonic acid to meet the application needs in various fields.

For 4,6-dinitroresorcinol-3-sulfonic acid, pay attention to many matters when storing and transporting.
This substance has certain chemical activity. When storing, the first choice should be a dry, cool and well-ventilated place. Because it is quite sensitive to temperature and humidity, if the environment is humid or the temperature is too high, it may cause chemical reactions and even affect the quality. Therefore, the warehouse needs to prepare temperature and humidity control equipment to ensure a suitable environment. In addition, it should be stored separately from substances such as reducing agents, acids, alkalis, etc., to prevent danger caused by interaction. Due to its active chemical properties, it may react violently when encountering the above substances, endangering safety.
When transporting, caution must also be taken. The packaging must be tight and firm to prevent damage and leakage during transportation. The packaging materials selected should have good corrosion resistance and sealing, which can effectively protect the substance. The transportation vehicle should also ensure that it is clean and free of other residual substances that may react with it. During transportation, high temperatures and open flames should be avoided, and the traffic should be smooth to reduce vibration and collision, so as to avoid changes in the substance due to external forces. At the same time, the transportation personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In case of an accident, they can respond quickly and properly to reduce the harm.