4,6-dichloro-1H-pyrrolo[3,2-c]pyridine

4,6-Diyne-1H-pyrrolido [3,2-c] pyridine is a special organic compound with unique physical properties. In its structure, the pyridine ring is cleverly fused with the pyrrole ring, and contains diyne groups, giving the compound unique physical properties.
In terms of appearance, 4,6-diyne-1H-pyrrolido [3,2-c] pyridine is usually a crystalline solid. Due to molecular interactions, such as van der Waals force, hydrogen bonds, etc., its molecules are arranged in an orderly manner to form a crystalline structure.
In terms of melting point, the compound has a high melting point due to the strong interaction between molecules. The conjugated structure of the diyne group enhances the intermolecular forces, so that more energy is required for melting to overcome these forces in order to break the orderly arrangement of molecules.
In terms of solubility, 4,6-diyne-1H-pyrrolido [3,2-c] pyridine has relatively good solubility in organic solvents, such as common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., because these solvents can form appropriate interactions with compound molecules, such as dipole-dipole interaction, dispersion force, etc., to help them disperse and dissolve. However, the solubility in water is poor, because the molecules are hydrophobic as a whole, and it is difficult to form effective interactions with water molecules.
In addition, the 4,6-diyne-1H-pyrrolido [3,2-c] pyridine conjugate system endows it with certain optical properties. Under the irradiation of specific wavelengths of light, absorption and emission phenomena may occur, which has potential application value in the field of optoelectronic devices.

To prepare 4% 2C6-diyne-1H-pyrrolido [3% 2C2-c] pyridine, there are various methods.
First, it can be prepared from a suitable starting material through a multi-step reaction. First, take the compound containing the pyridine ring, react with it with an alkynylating agent, and introduce the alkynyl group at a specific position in the pyridine ring. Among these, the alkynylation reaction conditions are quite critical, and the appropriate base, solvent and temperature need to be selected. If potassium carbonate is used as a base, in N, N-dimethylformamide (DMF) solvent, heating reaction can effectively combine halogenated alkynes with pyridine derivatives.
Then, the skeleton of pyrrolido [3% 2C2 - c] pyridine is constructed by intracellular cyclization reaction. This step may require specific catalysts, such as metal catalysts. For example, using copper salts as catalysts can promote the formation of intracellular rings and target structures in the presence of appropriate ligands.
Second, a reasonable synthesis route can be considered, which can be achieved by a "one-pot method" or a series reaction. First, the pyridine derivatives are reacted in the same reaction system with reagents containing alkynyl groups and potential pyrrole ring structures. By skillfully regulating the reaction conditions, the multi-step reactions can occur in sequence, reducing the separation steps of intermediates and improving the synthesis efficiency. < Br >
Or we can learn from the synthesis strategy of similar structures in the literature, and improve and optimize the existing method according to the structural characteristics of the target compound. Find appropriate reaction sequence, reagent dosage and reaction conditions to make the synthesis path simpler, higher yield, easy to operate and cost-controllable, so as to meet the needs of industrial production.

4,6-Dioxide-1H-pyrrolido [3,2-c] pyridine has a wide range of uses. In the field of medicine, due to its unique chemical structure and properties, it can be used as a key intermediate in drug synthesis. For example, for some new drugs with specific biological activities and pharmacological effects, in the development and synthesis process, 4,6-dioxide-1H-pyrrolido [3,2-c] pyridine can participate in the construction of the core skeleton. Through subsequent chemical modification and derivatization, it gives the drug the ability to target specific disease targets, such as the development of inhibitors for some cancer-related targets. It may play an important role. < Br >
In the field of materials science, it can be used as a raw material for the synthesis of functional materials. With its conjugated structure and electronic properties, through appropriate chemical modification and processing, materials with unique photoelectric properties may be prepared, such as applied to organic Light Emitting Diodes (OLEDs), organic solar cells and other optoelectronic devices, providing new ways to improve device performance and efficiency.
In the field of organic synthetic chemistry, 4,6-dioxide-1H-pyrrolido [3,2-c] pyridine, as a class of characteristic organic compounds, can participate in many organic reactions, such as cyclization reactions, substitution reactions, etc., to construct complex and diverse organic molecules, providing an effective tool for organic synthesis chemists to explore novel synthesis routes and strategies, helping to expand the molecular library of organic compounds, and promoting the continuous development and innovation of organic synthesis chemistry.

I am looking at your words, and I am inquiring about the market price of 4% 2C6-dioxide-1H-pyrrolido [3,2-c] pyridine. This is a rather professional chemical, and its market price often changes due to multiple factors.
First, quality is the key. Those with high purity and high quality must have a higher price than those with ordinary quality. The field of fine chemistry has strict quality requirements. If it is used for high-end applications such as pharmaceutical research and development, it requires extremely high purity, and the price is not cheap.
Second, the supply and demand situation has a great impact. If the market demand for this product is strong and the supply is limited, the price will rise; conversely, if the supply is sufficient and the demand is flat, the price may stabilize or even decline.
Third, the source channel is also related. Imported products or due to factors such as tariffs and transportation costs, the price is different from that of domestic products. And different manufacturers set different prices due to different production processes and cost control.
However, in "Tiangong Kaiwu", no price records directly related to this chemical were found. Because when "Tiangong Kaiwu" was written, modern chemistry had not yet developed to this point. Now if you want to know the exact market price of this product, you can consult chemical product trading platforms, chemical reagent suppliers, or communicate with industry professionals to obtain accurate price information.

In the preparation of 4,6-dioxy-1H-pyrrolido [3,2-c] pyridine, many things must be paid attention to.
Selection of the first raw material. The purity and quality of the raw material have a great impact on the purity and yield of the product. When the selected raw material has a high purity, and when it is stored and used, it needs to be properly protected to prevent it from being deteriorated due to moisture, oxidation and other conditions. If some moisture-sensitive raw materials must be stored in a dry environment, they should be used quickly to reduce their contact with air.
Control of reaction conditions is also crucial. In terms of temperature, this reaction is extremely sensitive to temperature. If the temperature is too high or too low, it may cause side reactions to occur, or reduce the reaction rate and yield. It is necessary to precisely control the reaction temperature, with the help of precise temperature control equipment, such as oil bath, water bath, etc., and monitor and adjust in real time. The reaction pressure cannot be ignored. Some reactions can proceed smoothly under specific pressure conditions, and the deviation of pressure or the reaction cannot achieve the desired effect. Professional pressure control devices need to be used to ensure stable pressure.
Furthermore, the choice and dosage of catalysts also need to be carefully considered. Appropriate catalysts can significantly improve the reaction rate and selectivity, but too much or too little catalyst dosage may affect the reaction process. The suitable catalyst should be selected according to the characteristics of the reaction and past experience, and its dosage should be accurately determined.
The choice of reaction solvent is also key. The solvent not only affects the solubility of the reactants, but also affects the reaction rate and selectivity. The selected solvent must have good solubility to the reactants and no side reactions with the reactants and catalysts. At the same time, the physical properties such as boiling point and volatility of the solvent also need to meet the needs of the reaction for subsequent product separation and purification.
The separation and purification of the product should not be underestimated. After the reaction, the product is often mixed with impurities such as unreacted raw materials, by-products and catalysts. Appropriate separation and purification methods, such as distillation, extraction, column chromatography, etc. should be used to obtain high-purity products. In this process, the separation method should be reasonably selected according to the physical and chemical properties of the product and the impurity, and the operation should be rigorous and meticulous to avoid product loss.