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What is the chemical structure of 4,5,6,7-tetrahydrothieno [3,2-c] pyridine hydrochloride (1:1)?
4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine and its carboxylate (1:1) is a special compound in organic chemistry. The analysis of the structure of this compound requires detailed investigation of the connection mode and spatial arrangement between its atoms.
View 4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine is a part of pyrrole ring, which is formed by fusing pyrrole ring with pyridine ring. Among them, the pyrrole ring has a five-membered ring structure, containing a nitrogen atom, and the lone pair electrons on the nitrogen atom participate in the conjugated system, so that the pyrrole ring is electron-rich. The pyridine ring is a six-membered ring structure, which also contains a nitrogen atom. However, the lone pair of electrons of the nitrogen atom does not participate in the conjugation, so that the pyridine ring is electron-deficient. After fusing the two, a unique electron cloud distribution and spatial configuration are formed.
And the carboxylate part is bound to the above pyrrolido-pyridine structure in a ratio of 1:1. In the carboxyl group, the carbon atom is connected to one oxygen atom by a double bond, and then to another oxygen atom by a single bond. This oxygen atom then forms a salt with a metal ion or an organic cation. This salt formation not only changes the charge state of the molecule, but also affects its physical and chemical properties.
When the two are combined at a 1:1 ratio, a 4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine carboxylate (1:1) is formed, which has the properties of both pyrrolido-pyridine and carboxylate. The atoms in the molecule interact with each other through covalent bonds and ionic bonds to construct a stable chemical structure, which exhibits unique behaviors in many chemical reactions and biological activities.
What are the main uses of 4,5,6,7-tetrahydrothiopheno [3,2-c] pyridine hydrochloride (1:1)?
4,5,6,7-tetrahydropyrrole [3,2-c] pyridine and its hydrochloride (1:1), this substance is widely used. In the field of medicinal chemistry, it is often used as a key intermediate to create various drugs. Because of its unique chemical structure, it can be precisely combined with specific targets in the body, and plays an important role in the development of drugs for neurological diseases and cardiovascular diseases. It can help chemists effectively regulate biological activities and improve drug efficacy.
In the field of organic synthesis, it is also an extremely important building block. With its structural characteristics, chemists can use a variety of organic reactions to skillfully integrate them into complex organic molecular structures, providing a feasible path for the synthesis of organic compounds with unique properties and functions, and expanding the boundaries of organic synthesis chemistry.
And in the field of materials science, it has also made its mark. Materials with special electrical, optical or mechanical properties, such as conductive polymers and fluorescent materials, can be prepared by chemical modification and polymerization, injecting new vitality into the development of materials science and promoting the birth and application of new functional materials.
What are the synthesis methods of 4,5,6,7-tetrahydrothieno [3,2-c] pyridine hydrochloride (1:1)?
The method of preparing 4% 2C5% 2C6% 2C7-tetrahydropyrrolido [3% 2C2-c] pyridine-1-carboxylic acid can be obtained from the following methods.
First, start with a suitable nitrogen-containing heterocyclic precursor. First, the basic structure of pyrrolido-pyridine is constructed through a specific cyclization reaction. During this process, the reaction conditions, such as temperature, solvent and catalyst dosage, need to be carefully regulated. If the temperature is too high or side reactions occur, if it is too low, the reaction will be delayed. The selected solvent must be able to dissolve the reactants well and be compatible with the reaction system. For example, the use of polar aprotic solvents may promote the reaction. After the cyclization structure is initially formed, it is carboxylated and modified. This step can be achieved by introducing a carboxyl-containing reagent to successfully connect the carboxyl group to the target position under a suitable reaction environment.
Second, we can consider starting from a simple organic compound and achieving it through a multi-step series reaction. First, we splice simple raw materials with an ingenious strategy to construct a preliminary carbon and nitrogen skeleton. For example, through the nucleophilic substitution reaction of enamines and halogenated hydrocarbons, part of the structure is built. Then by oxidation, rearrangement and other reactions, it is gradually converted into the target pyrrolido-pyridine structure. Finally, carboxylation was used to introduce carboxyl groups into the molecule, resulting in the preparation of 4% 2C5% 2C6% 2C7-tetrahydropyrrolio [3% 2C2-c] pyridine-1-carboxylic acid.
Third, we can also refer to the synthesis paths of related similar compounds to be optimized and improved. Analyze the problems and solutions encountered in the synthesis of similar structures, combine the characteristics of the target product, and fine-tune the reaction conditions and reagent selection. It is possible to explore a novel catalytic system to improve the efficiency and selectivity of the reaction and avoid unnecessary side reactions, so as to achieve the purpose of efficient synthesis of 4% 2C5% 2C6% 2C7-tetrahydropyrrolido [3% 2C2-c] pyridine-1-carboxylic acid.
What are the physical properties of 4,5,6,7-tetrahydrothiopheno [3,2-c] pyridine hydrochloride (1:1)?
The physical properties of 4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine hydrochloride (1:1) are as follows:
The morphology of this compound is mostly solid at room temperature, and the appearance is often white to off-white crystalline powder. This morphology is convenient for storage and subsequent processing.
In terms of solubility, due to the characteristics of hydrochloride, it exhibits good solubility in polar solvents. For example, it is easily soluble in water. As a common polar solvent, water can form a uniform dispersion system with the hydrochloride salt. This property makes it rapidly soluble and participates in related processes in reactions or formulations using water as a medium. At the same time, some lower alcohols, such as methanol and ethanol, also have a certain solubility. Alcohols have both certain polarity and organic group characteristics, and can interact with the compound to help dissolve.
Melting point is one of the important physical properties of substances. 4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine hydrochloride (1:1) has a specific melting point range. This melting point value is of great significance for identifying the compound and evaluating its purity. By accurately determining the melting point, if the measured value is consistent with the documented or theoretical value, it indicates that the purity of the compound is high; if there is a deviation, it may suggest the presence of impurities.
Stability, the hydrochloride is relatively stable under conventional conditions, but care should be taken to avoid being in a high temperature and high humidity environment. High temperature may cause changes in the internal structure of compound molecules, causing decomposition or deterioration; in high humidity environments, water molecules easily interact with hydrochloride salts, or cause deliquescence, which in turn affects their quality and performance. When storing, it should be stored in a dry and cool place to ensure the stability of its physical properties, so that it can play a stable role in various fields such as drug synthesis and chemical research.
What is the price range of 4,5,6,7-tetrahydrothiopheno [3,2-c] pyridine hydrochloride (1:1) in the market?
The price range of 4,5,6,7-tetrahydropyrrolido [3,2-c] pyridine hydrochloride (1:1) in the market is difficult to determine. The price is influenced by many factors, such as the quality, the difficulty of preparation, the situation of supply and demand, the amount of purchase, and the change of market conditions.
If the quality is high, the preparation requires complicated processes, scarce raw materials, and the market demand is greater than the supply, the price will be high; on the contrary, if the quality is normal, the preparation is easy, and the supply exceeds the demand, the price may be low. Furthermore, large purchases can often get preferential prices; sporadic purchases often have higher unit prices.
Looking at past market conditions, this compound hydrochloride (1:1), with excellent quality, may reach tens or even hundreds of gold per gram; those with inferior quality may reach tens or only a few gold per gram. However, this is only an approximate number. Market conditions change, and prices fluctuate accordingly. To know the exact price, you must consult merchants and suppliers in the market in detail, or refer to recent trading conditions to obtain a more accurate price range.