4-{5-[(4-nitrobenzyl)sulfanyl]-4-phenyl-4H-1,2,4-triazol-3-yl}pyridine

4 - {5 - [ (4 - nitrobenzyl) sulfanyl] -4 - phenyl - 4H - 1,2,4 - triazol - 3 - yl} pyridine, which is an organic compound. Looking at its complex structure, it contains nitrogen heterocycles, benzene rings and pyridine rings. Such organic compounds have a wide range of uses in the fields of medicine and materials.
In the field of medicine, or have pharmacological activity, and can be used as potential drug molecules. For example, the nitrogen heterocyclic structure is often related to biological activity, or can interact with targets in organisms to demonstrate antibacterial, anti-inflammatory, anti-tumor and other effects. By modifying and modifying this compound, it may be possible to optimize its activity, selectivity and pharmacokinetic properties to develop new therapeutic drugs.
In the field of materials, or due to unique electronic structure and molecular configuration, it exhibits special optoelectronic properties. Or it can be used as an organic semiconductor material for optoelectronic devices such as organic Light Emitting Diode (OLED) and organic solar cells to improve device performance and efficiency.
Although the specific characteristics and applications of this compound are not known in detail, by means of structural analysis and analogy of similar compounds, it can be known that it has potential important uses in medicine, materials and other fields. Scientists may be able to conduct in-depth research and tap its practical application value.

To prepare 4 - {5 - [ (4-nitrobenzyl) thio] -4 - phenyl - 4H - 1,2,4 - triazole - 3 - yl} pyridine, the method is as follows:
First take an appropriate amount of 4 - phenyl - 4H - 1,2,4 - triazole - 3 - thiol and place it in a clean reaction vessel. This compound is the starting material for the reaction, and its structure contains triazole ring and thiol group, which lays the foundation for the subsequent reaction.
Add an appropriate amount of base, such as potassium carbonate. The action of the base is to deprotonate 4-phenyl-4H-1,2,4-triazole-3-mercaptan and enhance its nucleophilicity. With gentle stirring, 4-nitrobenzyl halide, such as 4-nitrobenzyl chloride or 4-nitrobenzyl bromide, is slowly added dropwise. In this nucleophilic substitution reaction, the thiol negative ion attacks the benzyl carbon of 4-nitrobenzyl halide, and the halogen ion leaves to form a 5- [ (4-nitrobenzyl) thio] -4-phenyl-4H-1,2,4-triazole intermediate. After
, take this intermediate and place it in a new reaction vessel. Add an appropriate amount of halide containing pyridine structure, such as 4-halopyridine, and add suitable bases and catalysts, such as cesium carbonate and copper catalysts. Under the condition of heating and continuous stirring, a coupling reaction occurs. The halogen atom of the pyridine halide reacts with the specific position of 5- [ (4-nitrobenzyl) thio] -4-phenyl-4H-1,2,4-triazole. After a series of complex electron transfer and bonding processes, the target product 4-{ 5- [ (4-nitrobenzyl) thio] -4-phenyl-4H-1,2,4-triazole-3-yl} pyridine is finally formed.
After the reaction is completed, the target product can be purified by conventional separation and purification methods such as extraction and column chromatography for subsequent research and application.

4 - {5 - [ (4-nitrobenzyl) thio] -4 -phenyl - 4H - 1,2,4-triazole-3-yl} pyridine is an organic compound with unique physical properties.
Looking at its morphology, under normal temperature and pressure, it is mostly in a solid state. Due to the strong intermolecular force, the molecules are closely arranged, so it is stable. Its color is usually white to light yellow powder, and the appearance of this color is related to the absorption and reflection of light by various atoms and groups in the molecular structure.
When it comes to the melting point, the melting point of this compound is within a certain range, about [X] ° C to [X] ° C. The value of the melting point depends on the regularity of the molecular structure and the magnitude of the intermolecular force. In the molecular structure of the compound, the benzene ring, triazole ring and other structures endow it with certain rigidity and symmetry, which enhances the intermolecular force, resulting in a relatively high melting point.
In terms of solubility, it shows different performance in organic solvents. It has good solubility in polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF). This is because the polarity of these organic solvents matches the molecular polarity of the compound, and intermolecular interactions, such as hydrogen bonds, dipole-dipole interactions, etc., promote the dissolution of the compound. In non-polar organic solvents such as n-hexane and cyclohexane, the solubility is poor. Due to the weak intermolecular force between the non-polar solvent and the compound, it is difficult to overcome the intermolecular force of the compound to disperse in the solvent.
In addition, the density of the compound is about [X] g/cm ³, and the density is also closely related to the molecular structure. The type, number and arrangement of atoms in the molecule jointly determine its density value. Under common conditions, the chemical properties are relatively stable, but under specific conditions, such as high temperature, strong acid and alkali environment, some chemical bonds in the molecular structure may break or rearrange, thereby triggering chemical reactions.

4 - {5 - [ (4 - nitrobenzyl) sulfanyl] -4 - phenyl - 4H - 1,2,4 - triazol - 3 - yl} pyridine is an organic compound. This compound has many unique chemical properties.
As far as its stability is concerned, in the molecular structure, the pyridine ring is connected to the triazole ring by a specific connection method, and the triazole ring has a nitrobenzyl sulfanyl substituent, which gives it a certain stability. The existence of nitro groups, due to their strong electron absorption, will affect the distribution of molecular electron clouds, which in turn will play a role in stability.
In terms of solubility, since it is an organic compound, according to the principle of similarity solubility, it may have good solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide, etc. However, due to the polarity difference in the molecule, the solubility in water may be poor, because it is not a highly hydrophilic structure.
In terms of reactivity, both the pyridine ring and the triazole ring are electron-rich systems and can participate in the electrophilic substitution reaction. Pyridine nitrogen atom has a certain basic nature and can react with acids. The sulfur atom on the triazole ring has a lone pair electron, which can be used as a nucleophilic check point to participate in the nucleophilic substitution reaction. In addition, the nitro group of the nitrobenzyl moiety can undergo a reduction reaction and be converted into an amino group, thereby deriving more reaction pathways.
The chemical properties of this compound are due to its unique molecular structure, and the interaction of each part determines its behavior in different chemical environments.

I don't know the price of 4- {5- [ (4-nitrobenzyl) thio] -4-phenyl-4H-1,2,4-triazole-3-yl} pyridine in the market. This compound is not commonly available, or due to the complicated preparation process, the required raw materials are rare or the difficulty of synthesis is quite large, so it is less circulated in the market.
If explored in the chemical raw material market, its price is affected by many factors. One is the cost of raw materials. If the raw materials for synthesizing this compound are not easy to obtain and expensive, such as 4-nitrobenzyl related reagents, specific phenyl derivatives, etc., all are expensive, which will inevitably lead to an increase in the price of the final product. The second is the synthesis process. If the synthesis requires a multi-step reaction and harsh reaction conditions, such as high temperature, high pressure, and specific catalysts, it will not only increase the production cost, but also require extremely high production equipment, which will also increase the price.
In addition, the market supply and demand relationship is also the key. If the demand for this compound in a certain field suddenly increases, such as pharmaceutical research and development, material science and other fields find its unique application value, and the supply is limited, its price will also rise. On the contrary, if the demand is scarce, the price may be relatively stable or reduced.
However, I have not personally seen this compound traded in the market, so it is difficult to determine its exact price. If you want to know, you can consult chemical product suppliers, reagent sales platforms, or consult relevant industry information and market survey reports to obtain relatively accurate price information.