Competitive 4-(4-pyridinyl)thiazole-2-thiol;2-mercapto-4-(pyridine-4-yl) tniazole prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365036030 or mail to
info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365036030
Email: info@alchemist-chem.com
As a leading 4-(4-pyridinyl)thiazole-2-thiol;2-mercapto-4-(pyridine-4-yl) tniazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4- (4-pyridinyl) thiazole-2-thiol; 2-mercapto-4- (pyridine-4-yl) tniazole?
The two refer to the same chemical substance, and its chemical structure is: with the thiazole ring as the core, a thiol group (-SH) is connected at the 2 position of the thiazole ring, and a 4-pyridyl group is connected at the 4 position.
The thiazole ring is a five-membered heterocycle containing sulfur and nitrogen, which has specific aromatic and chemical activity. In this compound, the thiol group at the 2 position of the thiazole ring has a more active hydrogen atom on the sulfur atom, which is easy to participate in chemical reactions, such as the formation of derivatives such as thioethers and thioesters, which are widely used in the fields of organic synthesis and pharmaceutical chemistry. The 4-pyridyl group connected to the 4-position, the pyridyl ring is a nitrogen-containing hexamembered heterocycle, which is also aromatic. The existence of its nitrogen atom gives the pyridyl ring a unique electron cloud distribution, which can produce non-covalent interactions such as π-π stacking and hydrogen bonding with other molecules, which has a significant impact on the physical and chemical properties of the compound, such as solubility, stability and biological activity. This chemical structure endows the compound with diverse chemical properties and potential application value, and may have important uses in drug development, materials science and other fields.
What are the main uses of 4- (4-pyridinyl) thiazole-2-thiol; 2-mercapto-4- (pyridine-4-yl) tniazole?
4 - (4-pyridyl) thiazole-2-thiol; 2-mercapto-4 - (pyridyl-4-yl) thiazole, this compound has a wide range of uses and is used in many fields.
In the field of pharmaceutical chemistry, it is often used as a key intermediate. Due to the unique chemical structure of this compound, it plays an important role in drug synthesis. It can be introduced into the molecular structure of the drug through a specific chemical reaction to give the drug a specific pharmacological activity. For example, in the development of some antibacterial and antiviral drugs, it is expected to enhance the targeting and affinity of drugs to specific pathogens, thereby enhancing the efficacy of drugs.
In the field of materials science, it also shows potential value. Because of its sulfur and nitrogen heterocyclic structure, it may be used to prepare functional materials with special properties. For example, in the field of optical materials, if appropriately modified, it may be able to regulate the luminous properties of materials, used to develop new Light Emitting Diode (LED) materials to improve their luminous efficiency and color purity. In terms of electronic materials, it may improve the electrical properties of materials, providing new possibilities for the fabrication of high-performance semiconductor devices.
In addition, in the field of agricultural chemistry, 4- (4-pyridyl) thiazole-2-mercaptan; 2-mercapto-4- (pyridyl-4-yl) thiazole also has application potential. Or it can be used as a pesticide intermediate to synthesize new pesticides for pest control. By rationally designing its chemical structure, high-efficiency, low-toxicity and environmentally friendly pesticide products may be developed to meet the needs of modern agriculture for green and sustainable development.
In summary, 4- (4-pyridyl) thiazole-2-thiol; 2-mercapto-4- (pyridyl-4-yl) thiazole has important uses in medicine, materials, agriculture and other fields, providing key support for technological innovation and product development in related fields.
What are the synthesis methods of 4- (4-pyridinyl) thiazole-2-thiol; 2-mercapto-4- (pyridine-4-yl) tniazole?
To prepare 4- (4-pyridyl) thiazole-2-thiol (ie 2-mercapto-4- (pyridyl-4-yl) thiazole), there are many ways to synthesize it. One common one is to use 4-pyridyl formaldehyde, thioacetamide and ethyl haloacetate as starting materials. First, 4-pyridyl formaldehyde and thioacetamide are mixed in an appropriate solvent such as ethanol, catalyzed by acid or base, and the intermediate product is obtained through condensation reaction. This process requires moderate temperature control. If the temperature is too high, the side reaction will produce and the yield will drop; if the temperature is low, the reaction will be slow. Then, the intermediate product is reacted with halogenated ethyl acetate in an alkaline environment, such as an alcohol solution of sodium hydroxide. The strength and dosage of the base need to be precise, and the strong amount of the base is large, and the product or overreaction; the weak amount of the base is small, and the reaction is difficult to complete.
Another method is to use 4-pyridyl acetonitrile with carbon disulfide and halogenated hydrocarbons as raw materials. Let 4-pyridyl acetonitrile and carbon disulfide first form dithiocarboxylates under alkaline conditions, such as an alcohol solution of potassium hydroxide. This reaction requires the polarity of the solvent and the concentration of the base. Polarity discomfort and improper concentration all affect the reaction process. The later dithiocarboxylates react with halogenated hydrocarbons and cyclize The activity and structure of halogenated hydrocarbons are key, with high activity or suitable structure, and the reaction is easy to form, otherwise it will be unfavorable.
It is also started with 4-aminopyridine, mercaptoacetic acid, and vulcanization reagents. 4-aminopyridine and mercaptoacetic acid are first condensed, and then vulcanized and cyclized by vulcanization reagents. The choice of catalyst during condensation is important. Different catalysts have different reaction rates and selectivity. The type and dosage of vulcanization reagents also affect the purity and yield of the product. In short, the synthesis of this compound requires careful control of the reaction conditions in all methods to obtain satisfactory results.
What are the physicochemical properties of 4- (4-pyridinyl) thiazole-2-thiol; 2-mercapto-4- (pyridine-4-yl) tniazole?
4 - (4-pyridyl) thiazole-2-mercaptan; 2-mercapto-4 - (pyridyl-4-yl) thiazole, its physical and chemical properties are particularly important, and it is related to many applications.
Looking at its properties, it is either solid at room temperature, white to light yellow in color, and has a certain crystallinity, which is a characterization of its appearance. Regarding solubility, it has a certain solubility in common organic solvents, such as ethanol and acetone, but its solubility in water is quite limited. This property makes it necessary to operate according to its solubility laws in the process of separation, purification and preparation.
As for the melting point, after precise determination, it is about a certain temperature range. This temperature is the key node for the substance to change from solid to liquid, and it is of great significance for its identification and purity determination. Its chemical stability cannot be ignored. Under normal environmental conditions, its properties are relatively stable. However, in extreme chemical environments such as strong acids and bases, the molecular structure may change and chemical reactions occur.
In terms of chemical reactivity, the thiol base electrode in the molecule is active and can participate in many organic reactions, such as nucleophilic substitution reactions, and can interact with a variety of electrophilic reagents. This provides an opportunity for the synthesis of new compounds, which can be used to construct more complex molecular structures. The presence of pyridyl groups also endows molecules with unique electronic effects that affect their reactivity and selectivity.
The above physicochemical properties can be used as lead compounds in the field of medicinal chemistry to develop new drugs through their reactivity; in the field of materials science, due to their specific solubility and stability, they may be applied to the preparation of some functional materials. All of these highlight the value of in-depth exploration of the physicochemical properties of this substance.
What is the price range of 4- (4-pyridinyl) thiazole-2-thiol; 2-mercapto-4- (pyridine-4-yl) tniazole in the market?
I don't know the price range of 4- (4-pyridyl) thiazole-2-thiol; 2-mercapto-4- (pyridyl-4-yl) thiazole in the market. These two are very common and easily available, and they are rarely seen in various markets. It may be more common in specific chemical raw material trading venues, professional chemical reagent supply channels, and due to its use in professional chemical fields, it is not widely used in the mass market.
To know its price, you should consult professional chemical raw material suppliers and chemical reagent manufacturers. However, the price is also affected by many factors. Its purity is a key, and the higher the purity, the higher the price. If it is a high-purity scientific research-grade product, the price may be several times higher than that of industrial grade. Furthermore, the supply and demand also affect its price. If there are many people who want it, and if there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price may drop. And the production and transportation costs are also affected. If the production process is complicated and the transportation requires special conditions, the price will also be high.
From this perspective, it is difficult to determine the exact price range of these two things without consulting professional channels in detail.