4-[(4-methylphenyl)sulfanyl]thieno[2,3-c]pyridine-2-carboxamide

The chemical structure of 4 - [ (4-methylphenyl) thioalkyl] thiopheno [2,3-c] pyridine-2-formamide is also one of the organic compounds. Its structure is composed of three parts.
The first is the nucleus of thiopheno [2,3-c] pyridine, which is a fused heterocyclic structure. The thiophene ring fuses with the pyridine ring in a specific way to form a unique cyclic structure. The thiophene ring contains a sulfur atom, which is aromatic, and its electron cloud distribution is unique, which affects the chemical properties of the entire molecule. The pyridine ring contains nitrogen atoms and is also aromatic. The solitary pair electrons of the nitrogen atom endow the pyridine ring with alkalinity and the ability to interact with other molecules. After the two are fused, the stability and reactivity of the overall structure have their own characteristics.
The second is to connect the formamide group (-CONH ²) at the 2-position of the pyridine ring. This formamide group is a strongly polar group. Due to the existence of carbonyl (C = O) and amino (-NH ²), it can participate in the formation of hydrogen bonds, which has a great influence on the physical properties of compounds such as solubility, melting point, and boiling point. And formamide groups have high reactivity and can undergo various chemical reactions, such as hydrolysis and amidation. < Br >
The end is connected at the 4-position of the pyridine ring [ (4-methylphenyl) thioalkyl]. 4-methylphenyl contains a methyl-substituted benzene ring. The benzene ring has a highly conjugated system and is stable and has a certain electronic effect. The thioalkyl (-S -) connects the phenyl group to the pyridine ring, and the solitary pair electrons of the sulfur atom can participate in the conjugation, which affects the electron cloud distribution of the molecule. The introduction of this substituent not only changes the spatial structure of the molecule, but also affects the lipophilic and electronic properties of the molecule, and affects the interaction between compounds and other molecules. For example, it plays an important role in drug-target interactions.
The interaction of these three together determines the chemical structure and properties of 4 - [ (4-methylphenyl) thioalkyl] thiopheno [2,3-c] pyridine-2-formamide.

4 - [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide, this is an organic compound. Its main physical properties are as follows:
Appearance properties, usually in the form of a white to light yellow solid powder. In this state, the texture is fine, and when viewed under light, there may be a faint luster flickering, just like a delicate golden sand lying still. The cover is so aggregated because of its molecular arrangement and structure.
Melting point is between about 180-185 ° C. When the temperature gradually rises, the intermolecular force is gradually broken by thermal energy, the lattice structure disintegrates, and the substance slowly melts from solid to liquid. This temperature range is its inherent property and is also an important basis for identifying the compound.
Solubility, slightly soluble in water. In water, polar solvents are also, and the molecular structure of the compound is weak in polarity. According to the principle of similar compatibility, the affinity of the two is poor, so the solubility is limited. However, it is soluble in some organic solvents, such as dichloromethane, N, N-dimethylformamide, etc. In dichloromethane, it can be well dispersed, and the molecules interact with the solvent molecules to form a homogeneous system; in N, N-dimethylformamide, the solubility is better, because it can form a specific intermolecular force with the solvent to improve dissolution.
In terms of stability, under conventional environmental conditions, it is quite stable. When encountering extreme chemical environments such as strong oxidants and strong acids and alkalis, some chemical bonds in its molecular structure may be broken by impact, triggering chemical reactions and causing changes in its structure and properties. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place to avoid contact with the above chemicals to ensure the stability of its properties.

The synthesis method of 4- [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide has been known since ancient times. There are many methods, and each has its own advantages. Today, I will describe them in detail.
First, thiopheno [2,3-c] pyridine-2-formic acid is used as the starting material. First, it reacts with thionyl chloride to generate the corresponding acid chloride. This process requires attention to the reaction temperature and time. If the temperature is too high, side reactions will breed, and if the time is too short, the reaction will not be completed. After the acid chloride is formed, it reacts with an amine compound containing (4-methylphenyl) thio in the presence of a suitable base. The choice of base is quite critical, such as triethylamine, pyridine, etc. The amount of which is used is closely related to the reactivity. In this way, the target product 4- [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide can be obtained.
Second, starting from pyridine derivatives. First, specific substitutions are carried out on the pyridine ring, and sulfur atoms and thiophene ring structures are introduced to construct the parent nucleus of thiopheno [2,3-c] pyridine. This step requires the help of suitable catalysts and reaction conditions, such as palladium-catalyzed coupling reaction. Then, formyl groups are introduced at the 2-position of the parent nucleus, and then amidation is carried out to react with 4-methylthiophenol to form the target amide structure. Although this path is a little complicated, the reaction conditions are precisely controlled, and high-purity products can be obtained.
Third, thiophene derivatives are used as the starting materials. First, through the electrophilic substitution reaction on the thiophene ring, the pyridine ring fragment is introduced, and the thioether bond is formed at the same time to form a thiophenopyridine intermediate containing (4-methylphenyl) thio groups. Subsequently, the carboxylation reaction of the 2-position of the pyridine ring is carried out, and then the amidation step can obtain the target product. This method requires a deep understanding of the reactivity of the thiophene ring and a reasonable design of the reaction sequence in order to successfully achieve the synthesis goal.
All these synthesis methods require the experimenter to carefully operate, understand the delicacy of each step of the reaction, and carefully choose the appropriate method according to the purity, yield and cost of the desired product.

4- [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide is useful in many fields.
In the field of medicine, its role is quite obvious. This compound may have unique biological activities and can be used as the basis for potential drug development. Medical researchers often hope to use its structure as a blueprint to explore ways to intervene in specific biological pathways. For example, cell signaling pathways involved in certain diseases may be regulated by it. In cancer treatment research, it may be used to affect the process of cancer cell proliferation, differentiation and apoptosis, and is expected to become an important direction for the development of new anti-cancer drugs.
In the field of materials science, it also has its uses. Because of its special chemical structure, it may endow materials with unique electrical and optical properties. For example, in the preparation of organic optoelectronic materials, adding this compound may improve the material's electrical conductivity, light absorption and emission characteristics, and optimize the efficiency and performance of organic Light Emitting Diode (OLED), solar cells and other devices.
In the field of agricultural chemistry, there is also the possibility of application. Or it can be developed into a new type of pesticide, using its impact on specific biological activities to control crop diseases and pests. It can inhibit the growth and reproduction of harmful organisms with precise action mechanisms, and has advantages such as low toxicity and environmental protection compared with traditional pesticides, providing a new way for the development of green agriculture.
In summary, 4- [ (4-methylphenyl) thio] thieno [2,3-c] pyridine-2-formamide has potential applications in many fields such as medicine, materials science, and agricultural chemistry. It is an important object for researchers to explore and innovate.

4- [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide, the market prospect of this product is the focus of today's commercial attention.
Looking at the field of pharmaceutical research and development today, this compound may have unique pharmacological activities and can be used as a potential drug precursor. In recent years, the exploration of new heterocyclic compounds has become increasingly popular, and many studies have focused on the structure of thiophenopyridine, hoping that it can lead to innovative drugs. This amide derivative, or due to the combination of thiophenopyridine ring and thiobenzene in the structure, presents different chemical properties and biological activities. If it can be deeply explored in drug research and development, targets can be found, or new drug categories can be developed, it must have a place in the market.
Furthermore, in the field of materials science, such sulfur-containing heterocyclic compounds also have potential applications. With the increase in demand for functional materials, compounds with special optical and electrical properties have attracted much attention. The molecular structure of this substance may endow it with unique optoelectronic properties, which can be tried for the preparation of organic Light Emitting Diodes, sensors and other materials. If the research and development is successful, the market prospect is also limitless.
However, its marketing activities also pose challenges. The optimization of the synthesis process is crucial. If efficient and low-cost synthesis cannot be achieved, and mass production is limited, it will be difficult to enter the large-scale market stage. And drug development needs to go through long clinical trials, and safety and effectiveness must be strictly verified. In terms of material application, it also needs to face competition from congeneric products, and it is necessary to highlight unique advantages in order to emerge in the market. But in general, with time, in-depth research and development, 4- [ (4-methylphenyl) thio] thiopheno [2,3-c] pyridine-2-formamide may bloom in the pharmaceutical and materials markets and create a new situation.