4 4 Chlorobutyl Pyridine
pyridine pyrrole pyrazine piperidine piperazine

4-(4-chlorobutyl)pyridine

    Specifications

    HS Code

    434525

    Chemical Formula C9H12ClN
    Molecular Weight 169.65
    Appearance Typically a liquid
    Boiling Point Varies, but around a certain temperature range related to its molecular structure
    Melting Point Depends on its purity and molecular forces
    Density Specific value based on its mass - volume ratio
    Solubility In Water Limited or certain solubility depending on its polar nature
    Solubility In Organic Solvents Good solubility in some common organic solvents due to its organic nature
    Flash Point Characteristic value related to its flammability
    Pka Value Indicative of its acidic - basic properties in solution

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    General Information
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    Frequently Asked Questions

    As a leading 4-(4-chlorobutyl)pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4- (4-chloroprene) pyridine?
    (What is the main use of 4- (4-amino) pyridine?)
    Although the specific chemical substances such as (4- (4-amino) pyridine) are not recorded in Tiangong Kaiwu, the answer in the style of ancient Chinese can be as follows:
    Husband (4- (4-amino) pyridine) is widely used in various fields of modern chemistry. First, it is often a key raw material in the synthesis of medicine. Due to its special chemical structure, it can be introduced into drug molecules through various reactions to increase the activity of drugs and adjust their pharmacological properties. For example, when developing specific antibacterial drugs, the structural unit of (4-amino) pyridine may help the drug to accurately act on the target of bacteria and achieve the effect of sterilization and treatment.
    Second, in the field of materials science, it also has extraordinary uses. In the preparation of some functional materials, (4-amino) pyridine) can participate in polymerization reactions to construct polymer materials with unique electrical and optical properties. For example, the preparation of some photoelectric materials with sensitive response to specific wavelengths of light, the composition of (4- (4-amino) pyridine) can optimize the photoelectric conversion efficiency of the material, so that the material can be used in optoelectronic devices, such as Light Emitting Diodes, photodetectors and other fields, showing excellent performance.
    Furthermore, in the field of organic synthesis chemistry, (4- (4-amino) pyridine) is often used as an intermediate in organic synthesis. With the reactivity of its nitrogen-containing structure, it can undergo nucleophilic substitution, electrophilic addition, and other reactions with many organic reagents, resulting in a variety of organic compounds, which contribute to the development of organic synthetic chemistry, expand the synthesis path, enrich the variety of compounds, and help researchers explore a broader chemical world.
    What are the physical properties of 4- (4-chlorobutyl) pyridine?
    4- (4-cyanoethyl) pyridine is an organic compound, and its physical properties are as follows:
    In terms of pure 4- (4-cyanoethyl) pyridine is often a colorless to light yellow transparent liquid with a clear appearance. Its clear texture can be seen under normal light, without obvious impurities and suspended solids.
    Smell, it has a specific organic odor, but it is not a pungent and unpleasant odor. The odor has certain characteristics in organic compounds and can be used as a basis for preliminary identification.
    When it comes to boiling point, its boiling point is within a certain range due to factors such as intermolecular forces. Under normal pressure conditions, the boiling point is relatively high, which makes it more difficult to vaporize than some low-boiling substances during heating, and requires a higher temperature to convert into a gaseous state. This boiling point characteristic is crucial in the control of separation, purification and related chemical reaction conditions. It can be separated from the mixture according to the difference in boiling point by means of distillation.
    In terms of melting point, when the temperature drops to a specific value, 4- (4-cyanoethyl) pyridine will change from liquid to solid. The specific value of its melting point is determined by the molecular structure and the way of crystal accumulation. This parameter is of great significance to the study of the morphology and stability of the substance in low temperature environment. If the storage conditions are set, the melting point needs to be referred to.
    In terms of solubility, in organic solvents, such as common ethanol, ether, etc., 4- (4-cyanoethyl) pyridine exhibits good solubility. Due to the principle of similar miscibility, its organic structure is compatible with organic solvents. However, its solubility in water is relatively limited, because of the difference between molecular polarity and water molecular polarity, it can only be slightly soluble in water. This solubility characteristic has a significant impact on chemical synthesis and analysis, and suitable solvents can be selected for reaction, extraction and other operations. < Br >
    Density is also an important physical property. Compared with the density of water, the density of 4- (4-cyanoethyl) pyridine has a specific value. By density measurement, it can assist in judging the purity of the substance and estimating its stratification when it involves liquid-liquid separation and other operations.
    What are the chemical properties of 4- (4-chlorobutyl) pyridine?
    (4 - (4 - aminopropyl) pyridine is an organic compound, which has the following chemical properties:)
    First, this compound contains nitrogen atoms, and the nitrogen in the pyridine ring and the aminopropyl group has lone pairs of electrons, so it presents a certain alkalinity. In an acidic environment, nitrogen atoms receive protons and form positively charged ions. For example, in the case of strong acids, the nitrogen atoms of the pyridine ring easily bind to protons to form pyridine salts, which can be used to separate and purify the substance.
    Secondly, the amino group in the aminopropyl group has an active hydrogen atom, which can participate in a variety of substitution reactions. When reacting with acyl chloride, amino hydrogen will be replaced by acyl groups to form amide compounds. This reaction is often used in organic synthesis to construct complex molecular structures containing amide bonds.
    Furthermore, the pyridine ring has certain stability and aromaticity due to the conjugation system. However, the carbon atoms on the pyridine ring can undergo electrophilic substitution reactions under specific conditions, such as under suitable catalysts and reaction conditions, it can be substituted with electrophilic reagents such as halogenated hydrocarbons, and new substituents can be introduced on the pyridine ring, thereby changing the properties and functions of the compound.
    In addition, the carbon-nitrogen and carbon-carbon bonds in aminopropyl may break under the action of strong oxidants. In case of strong oxidizing substances, the structure of aminopropyl may be changed, affecting the chemical properties and functions of the whole molecule.
    (These chemical properties of this compound make it show important application value in many fields such as organic synthesis and medicinal chemistry.)
    What are the synthesis methods of 4- (4-chlorobutyl) pyridine?
    To prepare 4- (4-cyanophenyl) pyridine, there are many methods for synthesis, and the following are the common methods.
    One is the nucleophilic substitution method. Using 4-halopyridine and 4-cyanophenyl derivatives as raw materials, under the action of suitable bases and catalysts, the nucleophilic substitution reaction is obtained. This reaction requires active halopyridine, such as 4-chloropyridine or 4-bromopyridine, and a suitable base, such as potassium carbonate, sodium carbonate, etc., to promote the reaction. The catalysts used are often copper salts or palladium salts, such as cuprous iodide, tetra (triphenylphosphine) palladium, etc., which can improve the reaction efficiency.
    The second is the transition metal catalytic coupling method. The coupling reaction of 4-pyridyl boronic acid (or borate) with 4-halobenzonitrile is catalyzed by transition metals. Among them, the palladium-catalyzed Suzuki coupling reaction is quite commonly used. 4-pyridyl boronic acid and 4-bromobenzonitrile are reacted at appropriate temperatures in the system of palladium catalysts (such as tetra (triphenylphosphine) palladium), bases (such as potassium carbonate aqueous solution) and organic solvents (such as toluene, dioxane, etc.). Through a series of complex coordination, oxidative addition, transmetallization and reduction elimination steps, the target product 4- (4-cyanophenyl) pyridine is generated.
    The third is the cyclization reaction method. Compounds containing precursors of pyridine and benzonitrile structural fragments can be designed to construct the target product through intramolecular cyclization. For example, aniline and pyridine derivatives with specific substitutions are used as starting materials, and cyclized precursors are formed through multi-step reactions, and then cyclized under appropriate conditions. This process may involve reaction steps such as dehydration and loop closure. Fine control of reaction conditions, including temperature, reaction time and the proportion of reagents used, can be used to efficiently generate 4- (4-cyanophenyl) pyridine.
    There are various methods for the synthesis of 4- (4-cyanophenyl) pyridine, each method has its own advantages and disadvantages. The practical application requires comprehensive consideration of factors such as raw material availability, cost, reaction conditions, and purity and yield of target products. Select the appropriate synthesis route.
    What are the precautions for storing and transporting 4- (4-chlorobutyl) pyridine?
    For saltpeter, there are many things that should be paid attention to in the matter of storage and transportation.
    The first thing to talk about is its flammability and explosive nature. Saltpeter is very easy to burn and explode in case of open flames and hot topics. Therefore, in the storage place, it must be kept away from fire and heat sources, and fireworks are strictly prohibited. And its storage environment should be dry, cool and ventilated to prevent moisture and deterioration, causing its chemical properties to be unstable and causing disasters. The building of the warehouse should also have good fire protection and explosion-proof performance, and should be equipped with complete fire protection facilities, such as fire extinguishers, fire sand, etc., in case of emergency.
    When transporting, saltpeter must be carried by a special means of transportation. Transportation vehicles should be equipped with good grounding devices to prevent static electricity accumulation from causing explosions. Escorts must be familiar with the characteristics of saltpeter and emergency disposal methods, always pay attention to the transportation situation on the way, and if there is any abnormality, quickly dispose of it properly.
    Furthermore, the compatibility of saltpeter with other things should not be ignored. It should not be mixed with reducing agents, acids, active metal powders, etc., because they meet, it is easy to cause violent chemical reactions, resulting in danger. In the place of storage, all kinds of chemicals must be stored in separate warehouses according to their nature to avoid the risk of interaction.
    In addition, the system of safety management is indispensable. In the place of storage and transportation, detailed warehousing registration, inspection and inspection systems should be established. Regular maintenance and repair of storage equipment and transportation tools to ensure their safety performance. Employees also need to receive regular safety education and training to improve their safety awareness and emergency response capabilities.
    In short, the storage and transportation of saltpeter is a matter of safety. Only by paying attention to everything and following the norms can we ensure that nothing goes wrong and avoid disasters.