4-(4'-bromophenyl)-2,6-Di(2-pyridyl)pyridine

4- (4 '-bromophenyl) -2,6 -bis (2-pyridyl) pyridine is one of the organic compounds. Its main application fields are quite wide, and it has significant effects in many aspects.
First, in the field of materials science, this compound is often the key raw material for the preparation of new photoelectric materials. Because of its special structure and unique photoelectric properties, it can be used in the research and development of organic Light Emitting Diodes (OLEDs). OLEDs have attracted much attention in the display field due to their advantages such as self-luminescence, wide viewing angle and fast response speed. 4- (4 '-bromophenyl) -2,6-bis (2-pyridyl) pyridine can optimize the luminous efficiency and stability of OLEDs, making the display screen clearer and brighter, and the colors are more realistic and rich, contributing greatly to the progress of display technology.
Second, in the field of coordination chemistry, this compound can be used as a ligand to form complexes with a variety of metal ions. Such complexes often exhibit unique structures and properties and are widely used in the field of catalysis. For example, in some organic synthesis reactions, the complex can be used as a highly efficient catalyst to accelerate the reaction process, improve the reaction yield, and has good selectivity, which can accurately promote the occurrence of specific chemical reactions, which is of great significance in the organic synthesis industry.
Third, in the field of biomedicine, it has also attracted increasing attention because of its certain biological activity. Studies have shown that it may participate in the interaction of certain biomolecules and have an impact on specific physiological processes in organisms. Although relevant research is still in the exploratory stage, with time, it may open up new paths for the development of new drugs and contribute to the cause of human health.
In summary, 4- (4 '-bromophenyl) -2,6-bis (2-pyridyl) pyridine has important application value in the fields of materials science, coordination chemistry and biomedicine, and has great potential for future development.

To prepare 4- (4 '-bromophenyl) -2,6 -bis (2-pyridyl) pyridine, there are several common methods.
One is a raw material containing pyridine and bromobenzene structures, which is prepared by nucleophilic substitution reaction. First, take an appropriate 2-pyridine derivative and react it with a base to form a nucleophilic intermediate. Then, the intermediate is mixed with 4-bromobenzene and reacted under an appropriate solvent and temperature. The solvent used can be selected from polar aprotic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), because it can promote the nucleophilic substitution reaction. The reaction temperature depends on the specific activity of the raw material, generally between 50 and 150 ° C.
The second is a coupling reaction catalyzed by transition metals. Palladium catalysts are often used as an example, such as palladium acetate (Pd (OAc) -2). 2-pyridyl boronic acid derivatives, 4-bromobenzene are placed in the reaction system together with palladium catalysts, ligands and bases. The ligand can be selected from 2,2 '-bipyridine, tri-tert-butylphosphine, etc., and the base can be selected from potassium carbonate (K _ 2O _ CO 🥰), sodium carbonate (Na _ 2O _ CO 🥰), etc. This reaction is mostly carried out in organic solvents, such as toluene, dichloromethane, etc. The reaction temperature is usually controlled at 80-120 ° C. With the help of transition metal catalysts, the formation of carbon-carbon bonds can be effectively promoted, so as to achieve the synthesis of the target product.
Furthermore, a multi-step reaction can also be considered to construct the target molecule. Intermediates containing partial structures are synthesized first, and then the parts are connected through functional group conversion and further reactions. For example, fragments containing pyridyl groups are synthesized first, and then bromophenyl is gradually introduced through halogenation and substitution, and finally the synthesis of 4- (4 '-bromophenyl) -2,6 -bis (2-pyridyl) pyridine is achieved. Each step of the reaction needs to be carefully adjusted according to the raw materials used and reaction conditions to achieve higher yield and purity.

4- (4 '-bromophenyl) -2,6' bis (2 'pyridyl) pyridine is an organic compound. Its physicochemical properties are quite important, and it is related to the application of this compound in various fields of chemistry and materials science.
First describe its physical properties. This compound may be a solid under normal conditions, with a specific melting point and boiling point. The melting point can reflect the strength of intermolecular forces. If the intermolecular forces are strong, such as hydrogen bonds, van der Waals forces, etc., the melting point will be higher. Its boiling point is also affected by molecular structure and interactions. If the molecular weight is large and the intermolecular forces are strong, the boiling point will be high. In addition, the solubility of this compound is also a key physical property. In organic solvents, such as common ethanol, dichloromethane, etc., or have a certain solubility, but the solubility in water is low. Because most of the molecular structures are hydrophobic groups, their hydrophilicity is weak.
Re-discussion of chemical properties. Because the molecular structure contains bromophenyl and pyridyl groups, the chemical activity is unique. Bromine atoms in bromophenyl groups can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Under appropriate conditions, bromine atoms can be replaced by other nucleophilic reagents, thereby introducing different functional groups to expand the application scope of compounds. Pyridyl groups are basic and can react with acids to form salts. At the same time, nitrogen atoms on pyridine rings can be used as ligands to coordinate with metal ions to form metal complexes, which is of great significance in catalysis, materials science and other fields. In organic synthesis, such compounds can be used as intermediates to form more complex organic molecular structures through a series of reactions, laying the foundation for the synthesis of new materials, drugs, and the like.

I have not been able to obtain the exact market price of 4- (4 '-bromophenyl) -2,6 -bis (2-pyridyl) pyridine. The price of this substance often varies due to various factors. The factors, such as production, quality, purchase quantity, market conditions, supply and demand.
If you want to buy a small amount for experimental research, in some chemical reagent sales, or due to the difficulty of preparation, the cost of raw materials, etc., the price may be high. And if the purchase quantity is quite large, such as industrial use, due to the scale effect, the price of single may drop.
Looking at the market of chemical raw materials, the price of fine chemicals often fluctuates. The emergence of new preparation methods, changes in raw material prices, and the impact of policies and regulations can all cause differences in their prices. Therefore, to know the exact price, it is advisable to consult chemical reagent suppliers or chemical product trading platforms to obtain the price range in real time. Or the prices of different merchants can be compared. Due to competition, the prices are also different.

The stability of 4 - (4 '-bromophenyl) -2,6 -bis (2-pyridyl) pyridine is related to many aspects. In the chemical environment, the structure has a deep impact on its stability. Looking at its structure, the pyridine ring is connected to the bromophenyl group, and the pyridine ring is aromatic, which can stabilize the molecule by conjugation effect. And the spatial resistance distribution of dipyridyl and bromophenyl groups also affects its stability. If the spatial resistance is appropriate, it can reduce the collision between molecules and maintain the stability of the structure; if it is too large, it may cause the structure to distort and damage its stability.
temperature is also a key factor. When the temperature is low, the molecular thermal motion is slow and the stability is good; when the temperature rises, the molecular thermal motion intensifies, the bond energy may be affected, and the stability will decrease. For example, in high temperature reaction systems, this compound may decompose due to the enhancement of the vibration of the bond.
The solvent environment should not be underestimated. Different solvent polarities are different, and the dissolution and interaction of compounds are different. Polar solvents may form hydrogen bonds or dipole-dipole interactions with the compound, which affects its stability. In non-polar solvents, the intermolecular forces are different from those in polar solvents, which will also change its stability.
The influence of impurities cannot be ignored. If the compound contains impurities, impurities or chemically react with the host molecule, or interfere with the normal arrangement of molecules, thereby changing the stability. Therefore, in order to maintain its stability, it is necessary to strictly control the impurity content. Under
light conditions, this compound may absorb photon energy to cause electron transitions, triggering photochemical reactions and impairing its stability. Therefore, when storing or using, it should be protected from strong direct light. In short, the stability of 4- (4 '-bromophenyl) -2,6-bis (2-pyridyl) pyridine is restricted by many factors such as structure, temperature, solvent, impurities and light, and it needs to be comprehensively considered in practical application to maintain its stability.