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What is the chemical structure of 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazol-3-yl) phenyl) -1,2,3, 6-tetrahydropyridine hydrochloride?
This is the formula of an organic compound, and it is difficult to draw its structure by the chemical method of ancient times in our country. However, with today's chemical knowledge, it can be analyzed as follows:
"4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine, hydrochloride", its core structure is 1,2,3,6-tetrahydropyridine ring, which is connected with a phenyl group at the fourth position. The third position of the phenyl group is substituted by a fluorine atom, and the fourth position is connected by a 1-methyl-1H-1,2,4-triazole-3-group. The overall structure is specific because it contains heteroatoms such as nitrogen and fluorine. And because it forms a hydrochloride salt, it has the characteristics of a salt.
Although it is difficult to describe in detail by ancient methods, today's chemical drawing software, such as ChemDraw, can accurately draw its structure, intuitively showing atomic connections and spatial arrangements. This compound may have potential uses in medicine, materials and other fields, all relying on today's chemical structure analysis and synthesis techniques.
What are the main uses of 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazol-3-yl) phenyl) -1,2,3, 6-tetrahydropyridine hydrochloride?
4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride, which is an organic compound. It has a wide range of uses and is often used as a key intermediate for active pharmaceutical ingredients in the field of medicine.
In pharmaceutical chemistry research, by modifying and modifying the structure of this compound, new drugs with specific pharmacological activities can be developed. For example, it may show affinity and regulatory effects on targets involved in certain diseases, thus providing potential for the treatment of diseases such as inflammation, tumors, and nervous system diseases. Due to its structure containing specific heterocycles and substituents, it can interact with proteins, enzymes and other macromolecules in vivo to play a role in regulating physiological functions.
In the field of materials science, this compound may have unique electrical and optical properties, so it has potential applications in the preparation of organic optoelectronic materials. Its structure can affect the charge transport, fluorescence emission and other characteristics of materials, or can be used to prepare organic Light Emitting Diodes (OLEDs), organic solar cells and other devices to improve device performance and efficiency.
In addition, in organic synthesis chemistry, it serves as an important intermediate, providing a basis for the construction of more complex organic molecular structures. Through various chemical reactions, it can be combined with other organic fragments to expand the structural diversity of compounds and lay the foundation for the synthesis of new functional materials and drugs.
What are the physical properties of 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazol-3-yl) phenyl) -1,2,3, 6-tetrahydropyridine hydrochloride?
4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride, this is an organic compound. Looking at its physical properties, under normal temperature and pressure, or in a solid state, mostly white to off-white crystalline powder, because many organic hydrochloride compounds have this form. The melting point and boiling point are crucial in determining the purity and thermal stability of the compound. However, there is no exact data yet. It is presumed that the melting point will be in a specific temperature range. Due to the presence of aromatic rings, heterocycles and various functional groups in the structure of the compound, the intermolecular forces cause the melting point to be relatively high; the boiling point may be in a higher temperature range due to the complex structure and large molecular weight.
In terms of solubility, due to the hydrochloride group, it may have a certain solubility in water, because hydrochloride can form hydrogen bonds with water molecules and other interactions; in organic solvents such as methanol, ethanol, dichloromethane, etc., the solubility may vary depending on the polarity of the solvent and the structural characteristics of the compound. Polar organic solvents may have better solubility than non-polar ones.
In addition, the compound may have hygroscopicity, because its hydrochloride part is easy to absorb water vapor in the air, and it is necessary to pay attention to moisture-proof when storing to prevent moisture absorption from changing its properties and affecting its quality and application. Overall, although detailed physical properties need to be determined experimentally and accurately, the above characteristics can be roughly inferred based on its structure.
What are the synthesis methods of 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazol-3-yl) phenyl) -1,2,3, 6-tetrahydropyridine hydrochloride?
To prepare 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride, there are various methods.
First, the corresponding pyridine derivatives can be started. First, take a suitable pyridine parent, and introduce fluorine-containing and triazole-containing substituents under specific reaction conditions. This process requires the selection of appropriate reaction reagents and catalysts, such as fluorohalogenated aromatics and triazole derivatives under the action of base and transition metal catalysts, through coupling reaction, fluorine and triazole substitutions are added based on the corresponding position of the pyridine ring, and then the pyridine ring is hydrogenated and reduced to obtain the tetrahydropyridine structure, and then form a salt with hydrochloric acid to obtain the target product.
Second, triazole derivatives can also be used as starting materials. First, triazole is modified to introduce suitable substituents to make it have an activity check point for reaction with pyridine derivatives. At the same time, fluorine-containing pyridine derivatives were prepared, and through the condensation reaction between the two, the key carbon-carbon bond or carbon-nitrogen bond was constructed to connect the triazole and the structural part of the pyridine. Then, through reduction, salt formation and other steps, 4 - (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride was finally obtained.
Third, the strategy of gradually constructing the ring system can also be adopted. First construct the fragments of fluorobenzene ring and triazole ring, and connect the two through appropriate reactions. After that, the pyridine ring is formed by cyclization reaction, and then the pyridine ring is hydrogenated to finally form a salt. This approach requires fine control of the reaction conditions at each step to ensure the selectivity and yield of the reaction.
All synthesis methods have their own advantages and disadvantages. In actual operation, it is necessary to carefully choose according to many factors such as the availability of raw materials, the difficulty of reaction conditions, cost and the purity of the target product.
What is the market outlook for 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazol-3-yl) phenyl) -1,2,3, 6-tetrahydropyridine hydrochloride?
4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride, which is an organic compound. Looking at its market prospects, it needs to be explored many times.
First, in the field of pharmaceutical research and development, such compounds containing specific heterocyclic structures often have unique biological activities. Or through in-depth pharmacological research, potential targets for disease treatment can be found, such as inhibition of specific kinases, or regulation of neurotransmitters. If its significant efficacy and good safety can be confirmed, it will definitely open up a broad pharmaceutical market. However, the research and development of new drugs is time-consuming, expensive and risky, and requires long clinical trials to obtain regulatory approval.
Second, in terms of materials science, such organic compounds may be modified to give them special optical and electrical properties. Such as the preparation of organic Light Emitting Diode materials, using their molecular structural properties to achieve high-efficiency luminescence. Or used to prepare new conductive materials to promote the miniaturization and high performance of electronic devices. However, material applications need to solve the problems of mass production process and cost control.
Third, in the field of agricultural chemistry, it may be developed as a new type of pesticide. With its mechanism of action against specific pests or pathogens, develop high-efficiency and low-toxicity pesticides. However, it is necessary to fully consider its impact on the environment and ecology to ensure that it meets environmental protection requirements.
Although 4- (3-fluoro-4- (1-methyl-1H-1,2,4-triazole-3-yl) phenyl) -1,2,3,6-tetrahydropyridine hydrochloride has potential application value in many fields, it still needs to overcome many technical, regulatory and cost obstacles if it is to be converted into actual market products. Only through comprehensive research and unremitting efforts can we gain insight into its true market prospects.