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What is the main use of 4- (2-Nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine
4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine, an organic compound with a wide range of uses.
In the field of medicine, its effect is significant. Many polydihydropyridine compounds have calcium channel blocking activity and can regulate the transport of calcium ions across cell membranes. Such compounds can be used to treat cardiovascular diseases, such as hypertension, angina pectoris, etc. 4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine may also have similar physiological activities. After research and optimization, it may be developed into a new type of cardiovascular drug, bringing good news to patients.
In the field of organic synthesis, it is also a key intermediate. Due to its unique molecular structure, containing dihydropyridine rings and many substituents, it can be reacted through various chemical reactions, such as nucleophilic substitution, oxidation and reduction, etc. Organic synthesis chemists can use this to prepare organic materials with specific functions and structures, natural product analogs, etc., to promote the development of organic synthesis chemistry.
In the field of materials science, it may exhibit unique optoelectronic properties. Some dihydropyridine derivatives can change their molecular structures under light and electrical stimulation, presenting special optical and electrical properties. 4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine or modified, used in optoelectronic devices, such as Light Emitting Diode, sensors, etc., contributing to the development of materials science.
What are the synthesis methods of 4- (2-Nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine
There are various methods for preparing 4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine. The common method is to use methyl acetoacetate, benzaldehyde and ammonium carbonate as materials, add a catalytic agent to an alcohol solvent, and control the temperature. During the reaction, the material is first dissolved in alcohol, gradually heated, and maintained at a suitable temperature. After a few hours, the product can be seen to separate. After the reaction is completed, it is cold, filtered to obtain a crude product, and then recrystallized in an alcohol solvent to obtain a pure product.
The second method is to replace methyl acetoacetate with ethyl acetoacetate, and the remaining material is similar to the corresponding method. First, each material is mixed in alcohol, assisted by a catalytic agent, temperature control at a certain degree, and reaction over time. After completion, through the steps of cooling, filtration, and recrystallization, the refined product can be obtained.
The third method, changing the catalytic agent or solvent, such as using a special catalyst, or choosing a different organic solvent, according to the previous steps, adjusting the conditions, can also achieve the purpose of synthesis. However, each method has its own length, and it is necessary to consider the cost, yield, purity and other factors according to the actual situation, and choose the appropriate one.
What are the physicochemical properties of 4- (2-Nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine
4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine, the physical and chemical properties of this compound are as follows:
Looking at its properties, it is mostly a crystalline solid under normal conditions, which is arranged in an orderly manner due to intermolecular forces. Its melting point is the key temperature for the transition of the state of matter, about [X] ° C. When the temperature rises to this point, the lattice can be overcome by thermal energy, the crystalline structure disintegrates, and it turns into a liquid state.
In terms of solubility, it has a certain solubility in organic solvents such as dichloromethane and N, N-dimethylformamide. This is due to the interaction between the compound molecule and the organic solvent molecule, such as van der Waals force and hydrogen bond, which promotes dissolution. However, the solubility in water is very small, because the hydrophobic part of its molecular structure accounts for a large proportion, and the affinity with water molecules is weak, following the principle of "similar miscibility".
Its stability is also an important property. It can be stable at room temperature and pressure and protected from light. However, in the case of strong acids and strong bases, the ester groups, nitro groups and other functional groups in the molecular structure are easily attacked, triggering hydrolysis and reduction reactions. Under light conditions, nitro groups may undergo photochemical reactions, resulting in structural changes.
The spectral properties of this compound also have characteristics. In infrared spectroscopy, at a specific wavenumber, such as the C = O stretching vibration peak of the ester group at 1700-1750 cm ¬ and the C-O stretching vibration peak at 1100-1300 cm ¬, its functional groups can be identified according to these characteristic peaks. In hydrogen nuclear magnetic resonance spectroscopy, hydrogen atoms in different chemical environments exhibit specific chemical shifts, which can help to analyze molecular structures.
The above physicochemical properties are of great significance for their applications in organic synthesis, drug research and development, and lay the foundation for designing reaction conditions, predicting reaction products, and evaluating their biological activities.
What is the price of 4- (2-Nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine in the market?
I have not heard of the price of "4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine" in the market. This compound, or a special chemical raw material, its price is determined, which is related to multiple ends.
First, it depends on the purity. If the purity is high and the impurities are rare, the difficulty of preparation will increase, and the price will also be expensive. If you want to use it as a high-purity reagent, you need a fine purification process, which is expensive and expensive.
Second, the yield is also the main reason. If the output of this product is scarce, the supply will not be sufficient, and the price will rise. On the contrary, if it is produced in large quantities, the scale effect will be obvious, and the cost will decrease and the price will also decrease.
Third, the difficulty of preparation also affects its price. Its synthesis requires complex steps, expensive raw materials, and special reaction conditions, and the cost is high and the price must be high.
Fourth, market demand is also critical. If an industry has a strong demand for this product, such as pharmaceutical research and development, which is regarded as an important intermediate, the price will also rise due to demand.
However, I do not know the exact price of the "4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine" in the current market. For more information, you can consult chemical reagent suppliers or professional chemical product trading platforms to obtain accurate figures.
What are the storage conditions for 4- (2-Nitrophenyl) -2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine?
4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine This substance is hidden in a way that is related to its properties. This substance may be sensitive to factors such as light, heat, and humidity.
When hiding, it is advisable to choose a cool, dry, and dark place. Those who cover light and heat can promote its transformation and qualitative change. If exposed to light, the energy of light quantum can stimulate molecules, initiate chemical reactions, and damage their structure. The same is true for heat, which increases the kinetic energy of molecules, promotes the speed of reactions, and makes them uneasy.
As for moisture, water vapor can interact with substances, or cause hydrolysis and other changes. If the environment is humid, water vapor will adhere to its surface and seep into it, causing various chemical changes and destroying its inherent properties.
is to store 4- (2-nitrophenyl) -2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine, which should be stored in a sealed container and placed in a cool, dry and dark place to keep it away from the disturbance of light, heat and humidity, and to maintain its quality. In this way, it can be stored for a long time without losing its properties for future use.