4 2 3 Dichlorophenyl 1 4 Dihydro 2 6 Dimethyl 3 5 Pyridinedicarboxylic Acid Methyl 1 Oxobutoxy Methyl Ester
pyridine pyrrole pyrazine piperidine piperazine

4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic acid methyl (1-oxobutoxy)methyl ester

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    402655

    Chemical Name 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic acid methyl (1-oxobutoxy)methyl ester

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    Frequently Asked Questions

    As a leading 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-Pyridinedicarboxylic acid methyl (1-oxobutoxy)methyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 4- (2,3-dichlorophenyl) -1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl (1-oxybutoxy) methyl ester?
    4- (2,3-dihydrobenzyl) -1,4-dihydro-2,6-diethyl-3,5-p-diacid, methyl (1-oxo-monoxy methyl) methyl ester, which is mainly used as a key intermediate in the field of organic synthesis.
    Looking at the structure of this compound, the many functional groups contained in it give it unique chemical reactivity. In the process of organic synthesis, with these activity checking points, structural modification and functional expansion can be achieved through various reactions. For example, its ester groups can be converted into carboxylic acids under hydrolysis conditions, or new ester compounds can be formed through alcoholysis reactions; while the dihydrobenzyl moiety, due to the activity of hydrogen on benzyl carbons, can participate in nucleophilic substitution, oxidation and other reactions.
    In addition, in the field of medicinal chemistry, such structures may have specific spatial configurations and electronic effects, or can be used as templates for lead compounds. After structural optimization, drugs with specific biological activities can be developed, such as potential anti-inflammatory and antibacterial effects.
    In the field of materials science, by polymerizing the compound or compounding it with other materials, special properties such as improving the solubility and thermal stability of the material can be imparted to the material. Overall, this compound has important applications in the fields of organic synthesis, drug development, and materials science.
    What are the synthesis methods of 4- (2,3-dichlorophenyl) -1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl (1-oxybutoxy) methyl ester
    To prepare this 4- (2,3-dihydrobenzyl) -1,4-dioxy-2,6-dimethyl-3,5-to its dicarboxylic acid, methyl (1-oxo-monoxy methyl) methyl, ester, can follow the following number method.
    First, start with 2,3-dihydrobenzyl alcohol, and first halogenate to convert the hydroxyl group into a halogen atom, such as sulfoxide chloride and its action to obtain 2,3-dihydrobenzyl halide. Then, it is reacted with a compound containing 1,4-dioxy-2,6-dimethyl-3,5-dicarboxylic acid structure under the action of a base, such as potassium carbonate, in a suitable solvent such as N, N-dimethylformamide, with nucleophilic substitution, 2,3-dihydrobenzyl is introduced. The resulting product is then esterylated with a suitable alcohol and an acid chloride or an acid anhydride, and under catalytic conditions, a (1-oxo-monooxy methyl) methyl and an ester group are introduced.
    Second, starting from 1,4-dioxy-2,6-dimethyl-3,5-dicarboxylic acid, it is first partially esterified to obtain the corresponding monoester. Using the activity of the carboxyl group in the monoester, it reacts with Grignard reagents such as 2,3-dihydrobenzyl magnesium halide to realize the access of 2,3-dihydrobenzyl group. Finally, the remaining carboxyl groups are esterified, and the (1-oxo-monooxy methyl) methyl group and ester group are introduced, which can be achieved by heating and refluxing with the corresponding alcohol under the catalysis of concentrated sulfuric acid.
    Third, with 2,3-dihydrobenzaldehyde as raw material, 2,3-dihydrobenzyl alcohol is first reduced by reduction reaction, such as reduction with sodium borohydride. Then it is made into the corresponding sulfonate, which can be obtained by reacting p-toluenesulfonyl chloride in pyridine. Then, the sulfonate is reacted with the compound containing 1,4-dioxo-2,6-dimethyl-3,5-dioxy-dioxy-to-its-diformic acid and (1-oxo-monooxy methyl) methyl, ester precursor under basic conditions. Sodium hydride can be selected for the base. In anhydrous tetrahydrofuran solvent, nucleophilic substitution is formed to form bonds to complete the synthesis of the target product.
    What are the physical and chemical properties of 4- (2,3-dichlorophenyl) -1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl (1-oxybutoxy) methyl ester
    (The following answer is in the style of ancient classical Chinese)
    This is a question about the structure of a specific organic compound. Its structure is complex and contains many groups in its name. The physical and chemical properties of such compounds are quite elegant.
    In terms of physical properties, because it contains various groups, it affects the intermolecular force. Such as ether groups, amino groups, carboxyl groups, etc., the existence of ether groups, or the intermolecular force changes, has an impact on its melting boiling point. Usually compounds containing such structures, if the molecular weight is moderate, may be liquid at room temperature. Its solubility is also affected by the group. The carboxyl group is hydrophilic and can form hydrogen bonds with water molecules, so the compound may have a certain solubility in water. However, other hydrophobic groups such as alkyl groups will limit its solubility. It is generally or slightly soluble in water, but soluble in some organic solvents, such as ethanol, ether, etc., because its molecules and organic solvent molecules can form similar intermolecular forces.
    When it comes to chemical properties, carboxyl groups are acidic and can neutralize with bases, such as reacting with sodium hydroxide to form corresponding carboxylic salts and water. Amino groups are alkaline and can react with acids to form salts. Ether groups are relatively stable, but under certain conditions, such as strong acids, high temperatures, etc., ether bond breaking reactions may occur. And different groups in the compound are adjacent or interact with each other, so that the reactivity is slightly different from that of a single group compound. The unsaturated structures such as alkenyl groups contained in it can undergo addition reactions, such as addition with hydrogen, and under the action of appropriate catalysts, unsaturated bonds can be converted into saturated bonds. At the same time, due to multiple activity check points in the structure, or reactions such as condensation and polymerization can occur to form polymer compounds.
    In short, this compound is of great significance in the field of organic chemistry due to its complex combination of groups and unique physical and chemical properties.
    4- (2,3-dichlorophenyl) -1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl (1-oxybutoxy) methyl, ester What is the price range in the market?
    The structure of this compound is complex. Although I have been studying chemistry for many years, its name is still a little unfamiliar. And the market price of the compound often changes due to various factors such as purity, origin, supply and demand, and there is no fixed number.
    I heard that in "Tiangong Kaiwu": "Things in the world vary from time to time and change according to the situation." The price of this compound in the market is also the same. You may need to consult various chemical raw material suppliers, or visit the place of chemical trading, and observe its market in detail to get its approximate price range.
    If you just speculate in vain, it is difficult to determine its price. However, based on my experience, if the purity of such compounds containing special groups is quite high and the preparation is difficult, the price may be expensive; if the preparation is slightly easier and the market supply is sufficient, the price may be slightly cheaper. In short, if you want to know the exact price range, you must go to the market in person and inquire from many parties.
    What is the safety and toxicity of 4- (2,3-dichlorophenyl) -1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl (1-oxybutoxy) methyl ester?
    Nowadays, there are 4- (2,3-dioxy benzyl) -1,4-dioxy-2,6-diethyl-3,5-dioxy acid, methyl (1-oxo-monooxy methyl) methyl, ether. What is the safety and toxicity of this substance?
    The safety and toxicity of this substance are really related to many considerations. Looking at its chemical structure, 4- (2,3-dioxobenzyl) -1,4-dioxo-2,6-diethyl-3,5-dioxo-diacid, methyl (1-oxo-monooxy-methyl) methyl, ether, contains a variety of chemical groups. The existence of dioxobenzyl, dioxy, diethyl and other groups may have a great impact on their properties.
    In terms of its safety, under normal conditions, if there is no external specific excitation, this compound may be able to maintain a relatively stable state. However, in case of extreme environments such as hot topics and open flames, it may cause chemical changes, or cause combustion and explosion. Its stability is not only related to the strength of the chemical bonds in the molecule, but also to the temperature and pressure of the surrounding environment.
    As for toxicity, the characteristics of the groups are also key. Some organic groups, or lipophilic, easily penetrate the biofilm and then interact with the molecules in the organism. Such as dioxybenzyl, or can interfere with the metabolic pathways in the organism and affect the normal physiological function of the cell. And if such compounds degrade in the environment, the toxicity of their degradation products should not be underestimated. Or because they enter the water body and soil, they affect the balance of the ecosystem and endanger the survival of animals and plants.
    In summary, this 4- (2,3-dioxybenzyl) -1,4-dioxy-2,6-diethyl-3,5-dioxy acid, methyl (1-oxo-monooxy methyl) methyl, ether, when used and stored, should be treated with caution, and its safety and toxicity should be studied in detail to avoid possible hazards.