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What is the chemical structure of (3S) -1-benzylpyrrolidin-3-yl methyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
This is the question of (3S) -1-benzylpyrrolidine-3-ylmethyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate. This compound, resolved according to chemical nomenclature, has a specific functional group and stereo configuration in its structure.
Looking at its name, (3S) -1-benzylpyrrolidine-3-ylmethyl, this part indicates that pyrrolidine is present in the structure and is attached to benzyl at position 1, the configuration at position 3 is S, and the substituent at position 3 is methyl. ( 4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate moiety, showing the existence of 1,4-dihydropyridine ring, with methyl substitution at the 2,6 position, 3-nitrophenyl at the 4 position, and S at the 4 position configuration, and dicarboxylate structure at the 3,5 position.
Its overall chemical structure is connected by pyrrolidine ring and 1,4-dihydropyridine ring with specific linking groups. Substituents at different positions on each ring give this compound unique chemical properties and spatial structure. The analysis of this structure is crucial for understanding its reactivity and pharmacological activity in the fields of organic synthesis and medicinal chemistry.
What are the physical properties of (3S) -1-benzylpyrrolidin-3-yl methyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
(3S) -1-benzylpyrrolidine-3-ylmethyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylic acid ester, which is an organic compound. Looking at its structure, it is complex and delicate, and is composed of many groups cleverly connected.
In terms of its physical properties, it is usually a solid, but its specific melting point, boiling point and other properties will vary depending on molecular interactions and group characteristics. In terms of solubility, due to the presence of both polar groups, such as dicarboxylic acid esters, and non-polar groups, such as benzyl and phenyl, in polar solvents such as methanol and ethanol, there is a certain solubility, but in non-polar solvents such as toluene and hexane, the solubility is relatively small.
Furthermore, its density is also closely related to the degree of molecular accumulation. The molecular structure of this compound is relatively compact, and its density is presumed to be moderate. As for the appearance, it is often white or off-white powder, which is related to its molecular arrangement and light scattering and absorption characteristics. The physical properties of this compound are of great significance in chemical research and practical applications, and can provide a key basis for its separation, purification, storage and application.
What are the synthesis methods of (3S) -1-benzylpyrrolidin-3-yl methyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
The synthesis method of (3S) -1-benzylpyrrolidine-3-ylmethyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate is due to the exquisite organic synthesis, many methods, and has evolved with the changes of times.
Synthesize this compound in the past, or follow the classical route. First, the pyrrolidine ring structure is constructed from suitable starting materials. An active benzyl halide can be selected, and a derivative containing pyrrolidine mother nucleus, under the catalysis of base, undergoes nucleophilic substitution reaction to introduce the 1-benzylpyrrolidine-3-yl moiety.
As for the dihydropyridine part, the strategy of Hantzsch reaction can be adopted. The 2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylic acid ester is constructed by condensation reaction with methyl acetoacetate derivatives, 3-nitrophenyl formaldehyde and ammonia sources in suitable solvents and temperatures. Thereafter, (3S) -1-benzylpyrrolidine-3-yl is connected to (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate through esterification. Pay attention to the precise control of reaction conditions, such as temperature and catalyst dosage, to prevent side reactions from occurring.
Today, with the advancement of organic synthesis technology, there may be novel methods. For example, the coupling reaction catalyzed by transition metals can be used to synthesize this compound more efficiently and selectively. Or it can be synthesized under mild conditions by enzyme-catalyzed reaction, and it can avoid many cumbersome steps and harsh reaction conditions in traditional methods, and improve the atomic economy and environmental friendliness of the reaction.
What are the application fields of (3S) -1-benzylpyrrolidin-3-yl methyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
(3S) -1-benzylpyrrolidine-3-ylmethyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate is an organic compound. Its application field is quite extensive.
In the field of medicinal chemistry, this compound may have potential medicinal value. Because its structure contains specific functional groups and structural units, or can interact with specific targets in organisms, it exhibits pharmacological activities, such as anti-inflammatory, anti-tumor, and regulation of cardiovascular system functions. Chemists can modify and optimize its structure to develop new drug molecules and find effective ways for the treatment of diseases.
In the field of organic synthetic chemistry, it is also an important synthetic intermediate. With its unique structure, chemists can use a variety of organic reactions, perform derivatization operations, build more complex organic molecular structures, expand the variety and quantity of organic compounds, and provide a key material basis for the development of organic synthetic chemistry.
In addition, in the field of materials science, or due to some special physical and chemical properties of the compound, it can be used to prepare materials with specific properties, such as functional materials with optical and electrical properties, which play a role in optoelectronic devices, sensors, etc., contributing to the innovative development of materials science.
What is the market outlook for (3S) -1-benzylpyrrolidin-3-yl methyl (4S) -2,6-dimethyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3,5-dicarboxylate?
(3S) - 1 - benzylpyrrolidine - 3 - ylmethyl (4S) - 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylate, this is a specific organic compound. Looking at its market prospects, it is really complex and changeable.
From the perspective of pharmaceutical research and development, it may have potential. At present, in the field of medicine, the exploration of new compounds is constantly in-depth, and many of them have unique structures. After research and mining, new medicinal activities can often be discovered. The structure of this compound may enable it to exhibit unique pharmacological effects on specific disease targets. However, the road of pharmaceutical research and development is full of thorns, and it needs to go through rigorous experiments. From cell experiments, to animal experiments, to human clinical trials, any link is related to success or failure. It takes a long time and costs a lot, and the prospect of finished drugs is unknown.
In the field of chemical materials, organic compounds are often important raw materials. If its synthesis process can be optimized and cost reduced, it may be able to find applications in material synthesis, such as for the preparation of polymer materials with special properties. However, the chemical market is highly competitive, and new materials are being introduced rapidly. In order to gain a place, it is necessary to meet many requirements such as performance and cost.
Furthermore, environmental factors also affect its market trend. The current environmental regulations are becoming stricter, and the production process of compounds must be restricted if there is a risk of high pollution and high energy consumption. If the development of green synthetic routes is in line with the general trend of environmental protection, it may gain a broader market space; otherwise, it is easily abandoned by the market.
In summary, (3S) - 1 - benzylpyrrolidine - 3 - ylmethyl (4S) - 2,6 - dimethyl - 4 - (3 - nitrophenyl) - 1,4 - dihydropyridine - 3,5 - dicarboxylate market prospects, based on pharmaceutical research and development achievements, chemical applications and environmental compliance and other multi-end, only to seize the opportunity, to meet the challenge, is expected to emerge in the market.