3H-Imidazo[4,5-c]pyridine, 4,6-dichloro-

4,6-Dichloro-3H-imidazolo [4,5-c] pyridine, the chemical properties of this substance are as follows.
Its appearance may be a solid state, because it contains chlorine atoms, the intermolecular forces are different, resulting in a solid state. The melting point of the genus is due to the fused ring structure of imidazolo-pyridine in the structure, and the introduction of chlorine atoms, which makes the intermolecular bonds more tightly, so the melting point may be higher.
On solubility, because the nitrogen atom in the molecule has a certain alkalinity, the presence of chlorine atoms enhances the hydrophobicity of the molecule. In aqueous solvents, its solubility is poor, because it is difficult to form an effective interaction between water molecules and the molecule; in organic solvents, such as dichloromethane, chloroform and other halogenated hydrocarbons, or with a certain solubility, because its structure and halogenated hydrocarbons have similar hydrophobicity, in line with the principle of similar miscibility.
In terms of chemical activity, its imidazole ring and pyridine ring conjugate system, which makes the electron cloud density distribution on the ring special. The chlorine atoms at positions 4 and 6 have high activity and are prone to nucleophilic substitution reactions. Due to the electron-absorbing effect of chlorine atoms, the carbon atoms connected to them are partially positively charged, and nucleophilic reagents are prone to attack this carbon site. For example, when reacted with sodium alcohol, corresponding ether derivatives can be formed; when reacted with amines, nitrogen-containing substitutes can be formed.
And due to the nitrogen-containing heterocyclic structure, nitrogen atoms can be protonated under acidic conditions, resulting in changes in their chemical properties. At the same time, the conjugate system makes this substance have certain aromaticity and can participate in aromatic electrophilic substitution reactions, but the reactivity and localization effect are different from typical benzene rings due to the combined effect of the electronic effect of chlorine atoms and nitrogen atoms.

4,6-Dichloro-3H-imidazolo [4,5-c] pyridine has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to synthesize compounds with specific biological activities. These compounds may have potential efficacy in the treatment of specific diseases, such as certain cancers, inflammation-related diseases, etc. Due to its unique chemical structure, it can interact with specific targets in organisms, affect relevant biological pathways, and then achieve therapeutic purposes.
In the field of materials science, it also has applications. Due to the physical and chemical properties imparted by its special structure, it can be used to prepare materials with special properties, such as optical materials, electronic materials, etc. In the field of optical materials, it can adjust the luminescence properties of materials; in the field of electronic materials, it may affect the conductivity and stability of materials, providing the possibility for the development of new materials.
Furthermore, in the field of organic synthesis, 4,6-dichloro-3H-imidazolo [4,5-c] pyridine is often used as an important starting material. Organic chemists can modify and derive its structure through various chemical reactions, construct complex and diverse organic molecular structures, enrich the types of organic compounds, and contribute to the development of organic synthetic chemistry. This substance has shown important value in many scientific fields due to its unique structure, promoting research and application in related fields.

To prepare 4,6-dichloro-3H-imidazolo [4,5-c] pyridine, the method is as follows:
Take appropriate starting materials first, usually compounds containing pyridine and imidazole structures. At the beginning of the reaction, it is necessary to create a suitable reaction environment, such as selecting an appropriate reaction solvent, to ensure that the reactants can be fully dissolved and conducive to the reaction. Commonly used solvents include polar organic solvents, which can promote the interaction between molecules and make the reaction occur smoothly.
In the reaction, the chlorination step is crucial. Chlorine-containing reagents, such as specific chlorination agents, can be introduced to replace them with corresponding check points in the starting materials to introduce chlorine atoms. This process requires precise control of reaction conditions, such as temperature, reaction time, and the proportion of reactants. If the temperature is too high or too low, the reaction may develop in an unfavorable direction, or the reaction rate may be too slow, or too many side reactions may be produced. Improper time control will also affect the purity and yield of the product.
During the reaction, the reaction process should be closely monitored. Analytical methods such as thin layer chromatography (TLC) are often used to gain timely insight into the degree of reaction, determine whether the reaction is completed, or whether the reaction conditions need to be adjusted.
When the reaction reaches the expected level, the reaction mixture system is obtained. Subsequent separation and purification steps are required to obtain pure 4,6-dichloro-3H-imidazolo [4,5-c] pyridine products. Column chromatography, recrystallization and other techniques can be used to remove unreacted raw materials, by-products and impurities to improve the purity of the product. Through this series of steps, the target product 4,6-dichloro-3H-imidazolo [4,5-c] pyridine can be obtained.

I don't know the price range of 3H-imidazolo [4,5-c] pyridine, 4,6-dichloro-in the market. In the market of chemical materials, the price of this compound often varies due to many reasons.
First, the difficulty of preparation is the main reason. If the synthesis method is complicated, multiple steps are required, and the raw materials are rare or the reaction conditions are harsh. If extremely low temperature, high temperature, or special catalysts are used, the cost will be high, and the price will also be high.
Second, the market supply and demand situation also has a great impact. If there is strong demand for it in many industries, such as pharmacies, which use it as a key intermediate, and the output is limited, the price will rise; on the contrary, if the demand is low and the output is high, the price may fall.
Third, the difference in purity is related to the price. For high purity, due to the complex refining process, the cost is high, and the price is higher than that for low purity.
Fourth, the supplier and the purchase volume also affect the price. Large factories supply, stable quality, and the price may be different; for those who buy large quantities, they often get preferential prices.
However, I do not know the detailed data of the current market situation, so it is difficult to determine its price range. For more information, please consult the chemical material supplier or check the information of the chemical product trading platform to obtain a near-real price.

The Common Quality Standards of 4,6-dichloro-3H-imidazolo [4,5-c] pyridine are related to its purity, impurities, appearance, etc.
Purity is the key indicator. High purity of 4,6-dichloro-3H-imidazolo [4,5-c] pyridine can be used in high-end chemical synthesis, pharmaceutical research and development and other fields. Usually its purity is required to be more than 98%, and even 99% or even higher. To measure its purity, high performance liquid chromatography (HPLC) is often used. This method has high accuracy and can clearly show the proportion of each component in the sample, which helps to determine the purity geometry of 4,6-dichloro-3H-imidazolo [4,5-c] pyridine.
Impurities also need to be strictly controlled. Organic impurities and inorganic impurities cannot be ignored. Organic impurities may originate from intermediates and by-products in the synthesis process. Inorganic impurities such as metal ions, etc., may be introduced by raw materials and reaction equipment. For organic impurities, in addition to HPLC, gas chromatography (GC) can also be used as a detection method. For the detection of inorganic impurities, inductively coupled plasma mass spectrometry (ICP-MS) can accurately determine the content of metal ions.
Appearance is also an important part of Quality Standards. 4,6-Dichloro-3H-imidazolo [4,5-c] pyridine should generally be white to off-white crystalline powder. If the color deviation, foreign matter mixed in, etc., all indicate that the product quality is questionable. By observing its appearance properties with the naked eye, supplemented by microscopic observation of crystal morphology, etc., the appearance quality can be further confirmed.
Melting point is also a factor to consider. Its melting point range is relatively fixed. If the melting point deviates from the normal range, it may suggest that the product purity is poor or there are impurities. Therefore, accurate determination of melting point is also a part of quality control. Melting point is often determined by capillary method or differential scanning calorimetry (DSC).
The moisture content should also not be underestimated. Excessive moisture may affect product stability, reactivity, etc. The moisture content is often determined by the Karl Fischer method, and the moisture content is generally required to be controlled at a specific low level, such as less than 0.5%. In this way, the quality of 4,6-dichloro-3H-imidazolo [4,5-c] pyridine can be guaranteed to meet the needs of various applications.