3h Imidazo 4 5 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

3H-imidazo[4,5-b]pyridine

    Specifications

    HS Code

    214959

    Chemical Formula C6H5N3
    Molecular Weight 119.125 g/mol
    Appearance Solid
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents

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    General Information
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    Frequently Asked Questions

    As a leading 3H-imidazo[4,5-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 3H-imidazo [4,5-b] pyridine?
    3H-imidazolo [4,5-b] pyridine is a class of heterocyclic organic compounds containing nitrogen. It has a wide range of uses and is often a key intermediate in the creation of new drugs in the field of medicinal chemistry. Due to its unique molecular structure, it can interact with specific targets in organisms, thus providing the possibility for the development of antibacterial, antiviral, antitumor and other drugs.
    In the field of materials science, it also has applications. Because of its certain optical and electrical properties, it can participate in the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED), organic solar cells and other devices, which are expected to improve the performance and efficiency of such materials.
    Furthermore, in the field of organic synthetic chemistry, 3H-imidazolo [4,5-b] pyridine can be used as an important synthetic building block. Chemists connect it with other organic fragments through various chemical reactions to build more complex and diverse organic molecular structures to meet the needs of different fields for special structures and functional compounds. In short, 3H-imidazolo [4,5-b] pyridine plays an indispensable role in many scientific fields and is of great significance to promote the development of related fields.
    What are the physical properties of 3H-imidazo [4,5-b] pyridine
    3H-imidazolo [4,5-b] pyridine is a kind of organic compound. Its physical properties are quite specific.
    When it comes to appearance, under normal circumstances, this substance is mostly crystalline solid, white or nearly white. When pure, it is crystal clear. It looks like a fine ice crystal, or shimmering under light.
    The value of its melting point is within a certain range. This temperature is the key node for a substance to change from a solid state to a liquid state. When heated near this temperature, the lattice structure gradually disintegrates, the molecules are energized and the movement intensifies, and then the solid state melts into a flowing liquid state.
    Boiling point is also an important physical property. Under specific pressure conditions, when the temperature rises to the boiling point, the substance rapidly converts from the liquid state to the gaseous state, and the molecules break free from the liquid phase and escape into space.
    In terms of solubility, in organic solvents, such as ethanol, dichloromethane, etc., there is a certain degree of dissolution. This is due to the specific interaction between the molecular structure and the organic solvent molecules, such as van der Waals force, hydrogen bond, etc., which can be uniformly dispersed in the solvent. However, in water, the degree of dissolution is quite limited. Due to the poor matching of the polarity of water and the molecular polarity of the substance, it is difficult to form an effective interaction, so it is not easily soluble.
    Density is also one of its physical properties, reflecting its mass per unit volume. This value is specific, and compared with other substances, it can be seen that its severity is different.
    In addition, the stability of this substance can also be described. Under normal environmental conditions, the structure is relatively stable, but in case of extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may be damaged, and chemical reactions occur, causing its physical properties to change.
    What is the chemical synthesis method of 3H-imidazo [4,5-b] pyridine
    The chemical synthesis method of 3H-imidazolo [4,5-b] pyridine has been around for a long time, and its method is exquisite and worth exploring.
    To synthesize this compound, one of the methods is to use a suitable pyridine derivative as the starting material. First, an appropriate substituent is introduced at a specific position on the pyridine ring. The selection of this substituent and the control of the reaction conditions are very important, which are related to the direction and effectiveness of the subsequent reaction. An active group, such as a halogen atom, can be introduced into the pyridine ring by means of an electrophilic substitution reaction.
    Then, the halogen-containing pyridine derivative is reacted with a nitrogen-containing heterocyclic precursor. This reaction needs to be carried out in the presence of a specific solvent and catalyst. Common solvents such as organic solvent dimethyl sulfoxide (DMSO) can provide a suitable environment for the reaction. The catalyst can be selected from alkali substances, such as potassium carbonate, etc., whose function is to promote the reaction and accelerate the formation and fracture of chemical bonds.
    During the reaction, the nitrogen-containing heterocyclic precursor and pyridine derivatives gradually build the unique structure of imidazolo [4,5 - b] pyridine through a series of complex chemical reactions. In this process, the reaction temperature and time need to be strictly controlled. Too high or too low temperature, too long or too short time may affect the purity and yield of the product. Usually the reaction temperature is controlled in a moderate range, such as between tens of degrees Celsius and hundreds of degrees Celsius, and the reaction takes several hours to fully proceed.
    After the reaction is completed, the product needs to be separated and purified. Classic separation methods such as column chromatography and recrystallization can be used to remove residual impurities in the reaction system, such as unreacted raw materials and by-products, to obtain high-purity 3H-imidazolo [4,5-b] pyridine. Although this purification process is complicated, it is essential to obtain a pure product.
    In summary, the synthesis of 3H-imidazolo [4,5-b] pyridine requires many fine operations from the selection of raw materials, the control of reaction conditions, and the separation and purification of the product to achieve satisfactory results.
    What is the price range of 3H-imidazo [4,5-b] pyridine in the market?
    I don't know the price range of 3H-imidazo [4,5-b] pyridine in the market. This compound may be useful in the field of chemical and pharmaceutical research and development. Its price is often influenced by a variety of reasons.
    First, the purity has a great impact on the price. If the purity is very high, it is close to the high-purity reagent level, suitable for fine chemical experiments or high-end pharmaceutical synthesis, and its price is high. Gai because of its complicated purification process, requires high-end technology and equipment, and the cost is high. And those with slightly lower purity can be used as general chemical raw materials, and its price is relatively easy.
    Second, the yield is also the key. If the production of this product is scarce, it is a scarce chemical, or because of the complex preparation process, the raw materials are rare, resulting in limited supply, the price will be high. On the contrary, if the output is considerable, the benefits of large-scale production appear, the cost will be reduced, and the price may be closer to the people.
    Third, the amount of market demand also affects its price. If the demand for this product is strong in fields such as pharmaceutical research and development, and the demand exceeds the supply, the merchant may raise the price. If the demand is flat, the supply exceeds the demand, and the price may be lowered.
    Fourth, the cost of raw materials is also a major factor. If the raw material price required for the preparation of 3H-imidazo [4,5-b] pyridine is high, or the supply of raw materials is unstable, the price of the final product will also be affected and fluctuate.
    However, I have not personally involved in the market business, so it is difficult to determine the specific price range. For more information, you can consult chemical raw material suppliers, chemical trading platforms, or people who specialize in the industry. They should be able to provide a more accurate price range based on real-time market conditions.
    What are the relevant safety precautions for 3H-imidazo [4,5-b] pyridine?
    3H-imidazolo [4,5-b] pyridine is an organic compound, and its safety precautions are described as follows:
    First, this substance has potential chemical activity and toxicity. Its chemical structure contains nitrogen heterocycles, some of which contain compounds of this structure or have toxic effects on living organisms. During operation, it is necessary to be fully armed, such as wearing laboratory clothes, gloves and protective glasses, to prevent skin contact and splashing into the eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention according to specific conditions.
    Second, in terms of storage, it should be stored in a cool, dry and well-ventilated place. Due to its chemical properties, it may react with air, moisture and light to cause deterioration or degradation. Be sure to keep away from fire sources, heat sources and strong oxidants to prevent fire and explosion accidents.
    Third, the compound may be difficult to degrade in the environment and will accumulate, posing a threat to the ecological environment. The waste generated during the experiment or production process should not be discarded at will. It should be properly disposed of according to the prescribed chemical waste treatment process to reduce the negative impact on the environment.
    Fourth, when using, it is necessary to operate in a fume hood to ensure effective ventilation, avoid the accumulation of vapor or dust in the air, and reduce the risk of inhalation. At the same time, the dosage and reaction conditions should be strictly controlled, and the standard procedures for experiment or production should be followed to avoid the danger caused by improper operation. Fifth, users should be fully aware of the characteristics and risks of 3H-imidazolo [4,5-b] pyridine, carry out relevant training, and be familiar with emergency treatment methods. In the event of leakage, fire and other accidents, they can respond quickly and correctly to minimize the harm.