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What are the chemical properties of 3H-Imidazo [4,5-b] pyridine, 6-bromo-
6-Bromo-3H-imidazolo [4,5-b] pyridine, this is an organic compound. It has many chemical properties and is remarkable due to its unique structure.
From the perspective of physical properties, the state, melting point, boiling point and other properties of this compound often depend on the intermolecular forces and the compactness of its structure. However, I do not know its exact physical properties, so I have not reviewed the relevant literature in detail.
In terms of chemical properties, the imidazolo-pyridine structure in its molecule contains nitrogen heterocycles, which makes it alkaline to a certain extent. The lone pair electrons on the nitrogen atom can bind to protons and are alkaline. The 6-position bromine atom gives it good reactivity and can participate in the nucleophilic substitution reaction. Under appropriate conditions, the bromine atom can be replaced by nucleophilic reagents, and a variety of compounds can be derived, opening up a broad path for organic synthesis.
Furthermore, its conjugate system makes the compound have certain electron delocalization characteristics, which affects its spectral properties and chemical stability. The conjugate structure often makes the compound absorb in the ultraviolet-visible region, which can be used for spectral analysis to identify it.
In addition, the chemical properties of the compound are also affected by the surrounding environment, such as solvents, temperatures, pH, etc. Under different conditions, its reactivity and reaction path may vary.
In conclusion, 6-bromo-3H-imidazolo [4,5-b] pyridine, with its unique chemical structure, has broad research and application prospects in the field of organic chemistry, or can be used in drug synthesis, materials science and many other aspects.
What are the common application fields of 3H-Imidazo [4,5-b] pyridine, 6-bromo
Eh! 6-Bromo-3H-imidazolo [4,5-b] pyridine is widely used in today's world.
First, in the field of pharmaceutical research and development, this compound is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can be combined with specific targets in organisms, which can help develop specific drugs for difficult diseases such as tumors and neurological diseases. Taking tumors as an example, through exquisite molecular design, drugs constructed from 6-bromo-3H-imidazolo [4,5-b] pyridine are expected to precisely act on specific proteins of tumor cells, inhibit their proliferation and induce their apoptosis, thus providing a new way to overcome the stubborn diseases of tumors.
Second, in the field of materials science, it can also be seen. It may participate in the synthesis of materials with special photoelectric properties. When copolymerized with specific organic or inorganic components, materials with unique responses to light and electrical stimulation can be prepared, which can be used in cutting-edge technologies such as organic Light Emitting Diode (OLED) and solar cells to improve device performance, such as enhancing the luminous efficiency of OLEDs and improving the photoelectric conversion rate of solar cells.
Furthermore, in the field of organic synthetic chemistry, 6-bromo-3H-imidazolo [4,5-b] pyridine provides a wealth of reaction possibilities for organic synthetic chemists. The activity of its bromine atom can trigger a variety of substitution reactions, coupling reactions, etc., through which complex and novel organic molecules can be constructed, which injects vitality into the development of organic synthetic chemistry and promotes the exploration and innovation of new reactions and methods.
What are the synthesis methods of 3H-Imidazo [4,5-b] pyridine, 6-bromo-
To prepare 6-bromo-3H-imidazolo [4,5-b] pyridine, it can be obtained by the following methods.
First, a suitable pyridine derivative is used as the starting material. First, bromine atoms are introduced into a specific position of the pyridine ring, which can be used by electrophilic substitution. Select brominating reagents, such as liquid bromine and N-bromosuccinimide (NBS), under suitable reaction conditions, such as in the presence of a catalyst, a specific temperature and a solvent environment, so that bromine atoms fall precisely at the desired position of the pyridine ring. Subsequent cyclization reaction, under appropriate reagents and conditions, the pyridine ring and the imidazole ring are cycled to obtain the target product.
Second, starting from imidazole derivatives. The imidazole ring is modified first, and then the pyridine ring part is introduced through a series of reactions. Common reactions in organic synthesis can be borrowed, such as nucleophilic substitution, condensation reactions, etc. When introducing the pyridine ring, it is necessary to pay attention to the reaction check point and selectivity, so that the pyridine ring is connected to the imidazole ring as expected, and the bromine atom is introduced either during the construction of the pyridine ring or in the subsequent reaction steps to obtain 6-bromo-3H-imidazolo [4,5-b] pyridine.
Third, based on the strategy of constructing heterocycles. The multi-component reaction is used to select the raw materials containing nitrogen, bromine and other necessary structural fragments. In a one-pot reaction, the reaction conditions and catalysts are cleverly designed to interact with each component, and the imidazolo [4,5-b] pyridine skeleton is constructed in one step or a few steps. At the same time, the precise introduction of bromine atoms at the 6 position is achieved. However, this path requires a deep understanding of the reaction activity and reaction process of each raw material in order to obtain the product with ideal yield and purity.
Each method has its advantages and disadvantages. The actual synthesis needs to be comprehensively weighed according to the availability of raw materials, the ease of control of reaction conditions, the requirements of yield and purity, and the optimal method is selected.
What is the price range of 3H-Imidazo [4,5-b] pyridine, 6-bromo in the market?
I don't know what the market price range is for 3H-imidazolo [4,5-b] pyridine and 6-bromine. This is a chemical substance today, and there is no such fine chemical compound trade in my era, and there is no relevant price to check.
If you want to know the price of this product, you can find it in today's chemical raw material trading market and chemical reagent sales platform. Or ask the merchants specializing in chemical products, who often know the current price of various chemical substances. Or you can refer to the relevant procurement information mentioned in academic literature, but these are mostly purchased for scientific research purposes, and the price may vary due to factors such as purchase quantity and purity.
If you want to get an accurate price, you need to comprehensively consider market supply and demand, manufacturers, product specifications and many other factors. The market is changing rapidly, and prices vary from region to region and supplier to supplier. Therefore, to know the exact price range, you need to look for it in detail in the current market information.
What are the safety and precautions of 3H-Imidazo [4,5-b] pyridine, 6-bromo-
6-Bromo-3H-imidazolo [4,5-b] pyridine, this is an organic compound. In terms of its safety, the first concern is toxicity. In animal experiments or limited human exposure studies, there are no detailed and clear toxicity data. However, many bromine-containing heterocyclic compounds with similar structures may be potentially toxic, such as damage to liver, kidney and other organs, so caution should be used.
In addition, its chemical properties are active, in case of strong oxidants, or react violently, and even cause explosions. When storing and using, it must be separated from strong oxidants. This compound may be flammable. Although its ignition point is not precisely known, it should be kept away from fire and heat sources under high temperature, open flame environment, or there is a risk of combustion.
In addition, contact with this substance should also be careful. If it comes into contact with the skin, it should be rinsed with a large amount of water immediately, and then according to the specific situation, it may be necessary to seek medical treatment; if it enters the eyes, it should be quickly rinsed with a large amount of water and seek medical attention as soon as possible. During operation, appropriate protective equipment should be worn, such as protective gloves, goggles, and gas masks, to avoid direct contact and inhalation.
For storage, it should be placed in a cool, dry and well-ventilated place, away from incompatible substances, to prevent dangerous reactions. When taking and weighing, be careful in the fume hood to prevent dust from spreading into the air and being inhaled by the human body.
In short, when handling 6-bromo-3H-imidazolo [4,5-b] pyridine, it is necessary to strictly follow the safety operating procedures and attach great importance to safety protection, so as to effectively avoid potential hazards.