3H-imidazo[4,5-b]pyridine, 5-chloro-

The chemical structure of 5-chloro-3H-imidazolo [4,5-b] pyridine is one of the structures of organic compounds. This compound contains the parent nuclear structure of imidazolo-pyridine, and is connected to a chlorine atom at a specific position, that is, the specific atomic check point formed by the fusing of the imidazolo ring and the pyridine ring.
Looking at the structure of imidazolo [4,5-b] pyridine, the imidazolo ring and the pyridine ring are fused in a specific way, and the two share part of the atoms to form a unique fused ring system. The 5-chlorine atom, according to the chemical nomenclature, is connected to the atomic position of the fused ring system with the specific number 5.
The structural properties of this compound make it show unique chemical activity and potential application value in many fields such as organic synthesis and medicinal chemistry. The existence of nitrogen atoms in its structure endows the molecule with certain alkalinity and coordination ability, or can participate in many chemical reactions to form novel compounds. The introduction of chlorine atoms may change the physical and chemical properties of the molecule such as electron cloud distribution and lipophilicity, which in turn affects its biological activity and pharmacological effects.
In summary, the chemical structure of 5-chloro-3H-imidazolo [4,5-b] pyridine has important significance and potential application prospects in chemistry and related fields due to its unique combination of thick rings and substituents.

5-Chloro-3H-imidazolo [4,5-b] pyridine, this is an organic compound. Its physical properties are quite important and are related to many practical applications.
Looking at its appearance, it often takes a white to light yellow crystalline powder shape, which is easy to identify and distinguish.
When it comes to the melting point, it is about 190-195 ° C. The melting point is one of the characteristics of the substance and is a key basis in the identification and purification process. At this temperature, the state of the substance changes from solid to liquid.
In terms of solubility, it has a certain solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In dichloromethane, due to the appropriate interaction between the two molecules, a uniform dispersion system can be formed; in DMF, with the strong polarity of DMF, it can interact with it to achieve dissolution. However, the solubility in water is very small, because the polarity of the molecular structure is not enough to fully interact with water molecules.
Stability is also an important property. Under conventional conditions, 5-chloro-3H-imidazolo [4,5-b] pyridine is relatively stable. When encountering strong oxidizing agents, strong acids or strong bases, the structure will be affected and chemical reactions will occur. For example, in a strong acid environment, nitrogen atoms may protonate, resulting in changes in the charge distribution of molecules, which in turn affect their chemical activity and properties.
The physical properties of 5-chloro-3H-imidazolo [4,5-b] pyridine lay the foundation for its application in chemical synthesis, drug development and other fields, and need to be deeply understood and utilized.

5-Chloro-3H-imidazolo [4,5-b] pyridine, this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to create new drugs. Due to its unique chemical structure, it can interact with many biological targets, providing an opportunity for the development of drugs for specific diseases. For example, in the study of anti-tumor drugs, it may be possible to design compounds with high selective inhibitory activity on tumor cells by means of structural modification, interfering with tumor cell growth and proliferation-related signaling pathways, and achieving anti-cancer effects.
It also has potential uses in materials science. After rational molecular design and modification, materials may be endowed with special optical and electrical properties. For example, introducing it into the organic Light Emitting Diode (OLED) material system may improve the material's luminous efficiency, stability and other properties, and contribute to the development of OLED technology.
Furthermore, in the field of pesticide chemistry, it can be used as a basic structural unit for building high-efficiency and low-toxicity pesticide molecules. Through its derivatization, pesticide products that are highly lethal to specific pests and have little impact on the environment and non-target organisms are developed, which contributes to sustainable agricultural development. In short, 5-chloro-3H-imidazolo [4,5-b] pyridine has shown important application value in many fields, providing an important material basis for innovation and development in various fields.

To prepare 5-chloro-3H-imidazolo [4,5-b] pyridine, the following ancient method can be followed.
First take the pyridine as the base, and introduce chlorine atoms in the appropriate position according to its structure. Pyridine can be reacted with chlorine-containing reagents, such as thionyl chloride, phosphorus oxychloride, etc., under suitable conditions. During the reaction, it depends on the change of temperature and time. If the temperature is too high, or side reactions are caused, the product is impure; if the temperature is too low, the reaction is delayed and the yield is not high. Generally speaking, the temperature is controlled at tens of degrees Celsius, and the reaction takes several hours to obtain chloropyridine derivatives. < Br >
Then this chloropyridine-containing derivative is used as a substance to make an imidazole ring. Nitrogen-containing reagents, such as cyanamide and amidine, are often used to react with it. This step also requires careful adjustment of the reaction conditions, such as pH and solvent selection. Choose a suitable solvent to help the reactants dissolve and promote the reaction. If the solvent is not appropriate, or the reactants are insoluble, the reaction is difficult to occur.
During the reaction process, it is often necessary to monitor by ancient methods, such as thin-layer chromatography, to observe the consumption of raw materials and the production of products. After the reaction is completed, pure 5-chloro-3H-imidazolo [4,5-b] pyridine can be obtained by separation and purification methods, such as distillation, recrystallization, etc. During distillation, it is divided according to the boiling point of the product and the impurity; for recrystallization, a suitable solvent is selected to separate the product into it and remove impurities.
Perform these methods, pay attention to safety, avoid reagents from hurting the body, and follow the rules of ancient laws and fine operation to obtain the target product.

I don't know what the price range of 3H-imidazolo [4,5-b] pyridine, 5-chlorine-is in the market. The price of these substances may vary due to quality, source, supply and demand.
If you want to know the details, you should go to the trading house of various chemical materials, or ask the industry experts. In ancient trade, you often need to visit the local people to inquire about their prices. In today's world, information is convenient, or you can find relevant prices on the websites and forums of chemical trading. However, this information also needs to be screened in detail, so that it may be false or outdated.
Or you can ask the suppliers of chemical raw materials, who are often aware of the changes in their prices. If this material is a commonly used chemical, the price may be relatively stable; if it is rare or new, the price may fluctuate due to difficulties in research and development and production.
I regret that I have not obtained the exact data to tell you the price range. I hope you can follow my words and explore it in relevant places to get a near-real price.