(3'S)-1',2',5,7-Tetrahydro-2'-oxospiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxylic acid

This is the name of an organic compound. According to its name, its chemical structure can be deduced. In this compound name, " (3'S) -1 ', 2', 5,7-tetrahydro-2 '-oxo-spiro [6H-cyclopento [b] pyridine-6,3' - [3H] pyrrolido [2,3-b] pyridine] -3-carboxylic acid".
The word "spiro" indicates that it is a spiro-ring compound, meaning that the two rings are connected by a common atom. In this compound, the two rings of 6H-cyclopento [b] pyridine and [3H] pyrrolio [2,3-b] pyridine are connected by a helical atom.
"1 ', 2', 5,7-tetrahydro" shows that four hydrogen atoms on the partial ring are reduced, that is, double bond hydrogenation. "2 '-oxo" shows a monocarbonyl group (C = O) at a specific position (2' position). "3-carboxylic acid" shows a carboxyl group (-COOH) at a specific position (3 position) of the main ring. < Br >
In summary, the chemical structure of this compound contains spiro rings, and there are specific substituents on the rings, such as carbonyl groups, carboxyl groups, etc., and some positions have the characteristics of hydrogen atom reduction. In this way, its chemical structure and morphology can be roughly outlined by means of naming rules.

(3'S) -1 ', 2', 5,7-tetrahydro-2 '-oxo-spiro [6H-cyclopento [b] pyridine-6,3' - [3H] pyrrolido [2,3-b] pyridine] -3-carboxylic acid, this compound is widely used in the field of medicinal chemistry.
Its structure is complex and delicate, and its function in drug development is crucial. It is often used as a key intermediate in many drug studies. Due to its unique molecular structure, the cap can be combined with specific biological targets, acting like a delicate key, adapting to a specific lock, thus exerting pharmacological activity.
Taking the development of anti-tumor drugs as an example, this compound can be chemically modified to adjust its affinity and specificity with tumor cell targets. By changing the peripheral substituents, its spatial conformation can be optimized to better fit the receptors on the surface of tumor cells, thereby interfering with the growth, proliferation and metastasis of tumor cells.
It also plays a role in the research of drugs for neurological diseases. It can enhance the effect on neurotransmitter receptors and regulate neurotransmitter transmission by structural modification, providing new opportunities for the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Furthermore, in the field of anti-infective drugs, (3'S) -1 ', 2', 5,7-tetrahydro-2 '-oxo-spiro [6H-cyclopento [b] pyridine-6,3' - [3H] pyrrolido [2,3-b] pyridine] -3-carboxylic acid may be able to inhibit the activity of key enzymes of pathogens by virtue of its structural characteristics, block the metabolic pathway of pathogens, and achieve the purpose of anti-infection.
In short, due to its unique structure, this compound has great potential in the process of drug creation, providing rich research materials and possibilities for overcoming various diseases.

To prepare (3 ′ S) - 1 ′, 2 ′, 5,7-tetrahydro-2 ′ -oxo-spiro [6H-cyclopento [b] pyridine-6,3 ′ - [3H] pyrrolido [2,3-b] pyridine] -3 -carboxylic acid, the method is as follows:
First, take a suitable starting material and undergo a multi-step delicate transformation. Or first take a cyclopentopyridine compound with a specific structure, supplemented by appropriate reagents and conditions, so that a specific position on the pyridine ring is introduced into the reaction check point. This process requires temperature control and timing to keep the reaction in the desired direction. < Br >
Then, the pyrrolidine structure is cleverly spliced with it. In this step, the condensation method may be used, and the force of the catalyst is used to combine the two to form a spiral ring structure. When reacting, carefully observe the ratio of solvent and reactant to achieve the best effect.
When the spiral ring is initially formed, a carboxyl group is introduced at a specific position. Or choose a suitable carboxylation reagent, according to the chemical rules, so that the carboxyl group just reaches the target check point. This step may require multiple optimizations, adjusting the reaction parameters, so that the purity and yield of the product are good.
After the reaction is completed in each step, the product is refined by extraction, column chromatography and other methods to remove impurities, and the pure product (3 ′ S) - 1 ′, 2 ′, 5,7-tetrahydro-2 ′ -oxo-spiro [6H-cyclopento [b] pyridine-6,3 ′ - [3H] pyrrolido [2,3-b] pyridine] - 3 -carboxylic acid can be obtained. The whole process requires fine operation, and according to the chemical principle and practice, this synthesis can be achieved.

(3 ′ S) -1 ′, 2 ′, 5,7 -tetrahydro-2 ′ -oxo-spiro [6H -cyclopento [b] pyridine-6,3 ′ - [3H] pyrrolio [2,3 - b] pyridine] -3 -carboxylic acid This substance has unique physical properties. Looking at its shape, at room temperature, or a crystalline body, crystal clear when pure, like a natural beauty jade, with a regular geometric shape, due to the orderly arrangement of molecules. Its color, or colorless to slightly yellow, pure color, like natural pure water, not stained with dust.
As for the melting point, after fine measurement, it is in a specific temperature range. This temperature is the break of the balance of forces between molecules, the boundary point of lattice disintegration, and reflects the stability of its internal structure. And this substance has different solubility in different solvents. In polar solvents, such as alcohols, because of the interaction between molecules and solvent molecules to form hydrogen bonds, it shows a certain solubility, just like fish get water and blend seamlessly; in non-polar solvents, such as hydrocarbons, the solubility is poor, and the two seem to be distinct and difficult to dissolve. This is due to the difference in molecular polarity.
In addition, its density is also a specific value, which reflects the compactness of its material, just like a scale to measure its internal compactness. Compared with similar compounds, the similarities and differences in the way of molecular accumulation can be seen. In short, (3 ′ S) -1 ′, 2 ′, 5,7 -tetrahydro-2 ′ -oxo-spiro [6H-cyclopento [b] pyridine-6,3 ′ - [3H] pyrrolio [2,3 -b] pyridine] -3 -carboxylic acid The physical properties of the compound are determined by its molecular structure, which are related to each other and together describe the unique physical appearance of this substance.

(3'S) -1 ', 2', 5,7-tetrahydro-2 '-oxospiral [6H-cyclopento [b] pyridine-6,3' - [3H] pyrrolido [2,3-b] pyridine] -3-carboxylic acid is widely used in the field of medicine. This compound has a unique chemical structure and shows potential in many drug development directions.
First, in the development of drugs for neurological diseases, it may modulate neurotransmitters and repair damaged neural pathways. Because of its structural similarities to neuroactive substances, it is expected to become a new drug lead compound for the treatment of epilepsy, Parkinson's disease and other diseases.
Second, in the field of anti-tumor drug exploration, this compound may interfere with the key metabolic pathway of tumor cells, inhibit the proliferation of tumor cells, and induce their apoptosis. With its precise effect on specific targets of tumor cells, it may provide new strategies for anti-tumor therapy.
Third, in the development of anti-inflammatory drugs, it can reduce the expression of inflammatory factors by regulating inflammation-related signaling pathways in the body, relieve inflammation, and become a new option for the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.
Fourth, for the development of immunomodulatory drugs, this compound may regulate the activity of immune cells, balance the body's immune response, or bring new ideas for the treatment of autoimmune diseases and immunodeficiency diseases.
In summary, (3'S) - 1 ', 2', 5,7 - tetrahydro - 2 '-oxospiral [6H - cyclopento [b] pyridine - 6,3' - [3H] pyrrolido [2,3 - b] pyridine] - 3 - carboxylic acids have broad prospects in the field of medicine and are worthy of in-depth research and exploration to explore more potential medicinal values.