3-Pyridinesulfonamide, N-(3-methoxy-5-methylpyrazinyl)-2-(4-(1,3,4-oxadiazol-2-yl)phenyl)-

This is a chemical substance with an extraordinary complex chemical structure. 3 - Pyridinesulfonamide, N- (3 - methoxy - 5 - methylpyrazinyl) - 2 - (4 - (1,3,4 - oxadiazol - 2 - yl) phenyl), looking at its name, it is made of many parts cleverly spliced together.
Starting from the pyridine sulfonamide, on the pyridine ring, the sulfonamide group is connected to it, which lays the basic skeleton of this compound. At the N position, it is connected to 3-methoxy-5-methylpyrazinyl. Methoxy and methyl are attached to specific positions of the pyrazine ring, and their existence may change the distribution of molecular electron clouds, affecting its physical and chemical properties.
Furthermore, the No. 2 position of the pyridine ring is connected to a phenyl group containing a specific substituent, and the No. 4 position of this phenyl group is connected to 1, 3, 4-oxadiazole-2-yl. The unique structure of the oxadiazole ring endows the whole molecule with different characteristics, or affects its reactivity, stability and biological activity.
The chemical structure of this compound is like a carefully constructed chemical labyrinth. Each part is interdependent and affects each other, and together determines its unique "behavior" and "character" in the chemical world.

3-Pyridyl sulfonamide, N- (3-methoxy-5-methylpyrazinyl) -2- (4- (1,3,4-oxadiazole-2-yl) phenyl) This material has many physical properties. Its appearance may be a solid in a crystalline state, the quality is dense and regular, and it may have a specific luster under light, just like the warmth of good jade.
Looking at its solubility, in organic solvents, such as dichloromethane, N, N-dimethylformamide, it can exhibit certain solubility characteristics, like fish getting water, and it is mixed with each other. However, in water, it is like oil floating in water, and it is difficult to mix, showing the characteristics of hydrophobicity.
When it comes to melting point, it is accurately determined to be within a certain temperature range. This temperature range is the key threshold for its transition from solid to liquid. It is like a checkpoint. Beyond this boundary, the material form changes.
Its stability is also worthy of attention. Under normal environmental conditions, it is like a calm old man, which can maintain the stability of its own structure and properties. In the case of extreme chemical environments such as strong acids and alkalis, or when a delicate flower encounters a strong wind, the structure is easily damaged and the properties change accordingly.
And its density, scientifically measured, presents a specific value. This value reflects its mass per unit volume, just like the standard for measuring its "weight", and occupies an important position in the characterization of material properties. Various physical properties are key elements for in-depth understanding of this object.

3-Pyridine sulfonamide,\ (N\) - (3-methoxy-5-methylpyrazinyl) -2- (4- (1,3,4-oxadiazole-2-yl) phenyl) This substance has a wide range of uses. In the field of medicine, it may be used as a key raw material for the development of new drugs. Due to its specific chemical structure, it may be able to precisely interact with biological targets in the body, which has potential efficacy in the treatment of certain diseases, such as causing inflammation against specific bacteria, or having anti-inflammatory effects; for specific tumor cells, it may inhibit its growth and spread.
In the chemical industry, it can be used as an intermediate for the synthesis of special functional materials. Through a series of chemical reactions, it is combined with other compounds to produce materials with unique properties, such as materials with special adsorption and stability, for separation, catalysis and other fields.
In agriculture, there may also be application value. Or it can be developed into a new type of pesticide, with its chemical properties, it has repellent and poisoning effects on specific pests, or has control effects on crop diseases, and compared with traditional pesticides, it may have the advantages of low toxicity, high efficiency and environmental friendliness, contributing to the sustainable development of agriculture.

To prepare 3-pyridine sulfonamide, N- (3-methoxy-5-methylpyrazinyl) -2- (4- (1,3,4-oxadiazole-2-yl) phenyl), the method is as follows.
First take appropriate raw materials, such as compounds containing pyridine structure, pyrazine structure and oxadiazole and phenyl related compounds. Pyridine sulfonyl chloride can be used as a starting material by nucleophilic substitution reaction to interact with amino-containing (3-methoxy-5-methylpyrazine) derivatives. This step requires selecting a suitable base, such as potassium carbonate, in a suitable solvent, such as dichloromethane or N, N-dimethylformamide, temperature-controlled reaction, so that the sulfonyl chloride and the amino group can be condensed smoothly, and the intermediate of pyridine sulfonamide and pyrazine is obtained.
Then, a reagent containing 4- (1,3,4-oxadiazole-2-yl) phenyl is prepared. The desired phenyloxadiazole intermediate can be obtained by dehydration and condensation reaction of benzene derivatives containing carboxyl groups with hydrazine-containing 1,3,4-oxadiazole compounds, such as in the presence of condensation agents such as dicyclohexylcarbodiimide (DCC) and catalyst 4-dimethylaminopyridine (DMAP).
Finally, the above two intermediates are connected by suitable coupling reactions. Transition metal catalysis, such as palladium-catalyzed coupling reactions, can be used. Using palladium acetate as catalyst and bipyridine as ligand, in the presence of base, the reaction is heated in a suitable solvent to connect the two parts, and the final target product is 3-pyridine sulfonamide, N- (3-methoxy-5-methylpyrazinyl) -2- (4- (1,3,4-oxadiazole-2-yl) phenyl). After the reaction is completed, the pure product can be obtained by separation and purification methods, such as column chromatography.

3-Pyridine sulfonamide,\ (N- (3-methoxy-5-methylpyrazinyl) -2 - (4- (1,3,4-oxadiazole-2-yl) phenyl) \) This compound has many safety precautions, and I will state them in detail.
First words storage. This compound should be kept in a cool, dry and well-ventilated place. If placed in a high temperature or humid place, it may change its chemical properties or cause dangerous chemical reactions. For example, high temperature may cause it to decompose, release harmful gases, and endanger the surrounding environment and human safety.
Furthermore, operation. When handling this material, it is necessary to wear appropriate protective equipment. Protective gloves, goggles and protective clothing are all indispensable. Because of its irritation, if accidentally touched with the skin, it can cause redness, swelling and pain; if it enters the eyes, it will be more harmful, or damage the vision. The operation process should also avoid dust, due to inhalation of its dust or serious damage to the respiratory tract, such as causing cough, asthma, long-term exposure may even damage lung function.
And on disposal. Do not discard this compound at will. Relevant regulations and procedures should be followed and properly disposed of. If discarded indiscriminately, it may seep into the soil and water sources, pollute the environment and endanger the ecological balance. The correct method may be handed over to a professional waste disposal agency to ensure safe disposal.
When transporting, also need to be cautious. It is necessary to choose the appropriate packaging and transportation method according to its characteristics. Make sure that the packaging is intact during transportation and does not leak. Otherwise, if it leaks, it may cause serious safety accidents during transportation and endanger the safety of transporters and surrounding people.
All these safety precautions are related to human life and environmental safety and should not be ignored. When handling, storing, discarding and transporting this compound, it must be strictly followed to ensure safety.