3-Pyridinemethanamine, 伪-(trifluoromethyl)-

3-Pyridylmethylamine, pseudo- (trifluoromethyl), has a wide range of uses. In the field of medicine, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it is endowed with different activities and characteristics of drugs, which can precisely act on specific biological targets, or regulate physiological functions, or resist disease intrusion.
In the field of organic synthesis, this compound also occupies an important position. It can be used as the cornerstone of building complex organic molecules. Through a variety of chemical reactions, such as nucleophilic substitution, addition, etc., it is ingeniously combined with many reagents to build complex organic compounds with specific functions, contributing new properties to the fields of materials science and fine chemistry.
Furthermore, in the path of scientific research and exploration, it is a powerful tool for studying intermolecular interactions and reaction mechanisms. Scientists can gain insight into the nature of chemical processes by observing and analyzing their participation in reactions, and contribute to the development of theoretical chemistry. This will guide more efficient and accurate synthesis strategies and promote the overall progress of chemistry.

(Note: "3 - Pyridinemethanamine, pseudo- (trifluoromethyl) -" The standard Chinese name should be "3 - pyridinemethanamine, pseudo- (trifluoromethyl) -", the following shall prevail to answer)
3 - pyridinemethanamine, pseudo- (trifluoromethyl) -, the physical properties of this substance are particularly important, related to its application in various fields.
Looking at its appearance, under normal temperature and pressure, it is mostly colorless to yellowish liquid, with uniform texture and good fluidity. The appearance of this color state is determined by its molecular structure and electronic transition characteristics. The smell is unique and slightly irritating, and the smell can make the nasal cavity feel obvious, but it is not unbearable. The production of this smell is related to the special structure of nitrogen-containing groups and trifluoromethyl groups in the molecule.
When it comes to the melting point, its melting point is very low, about -30 ° C. Under this temperature, the substance gradually changes from liquid to solid, and the molecular movement is greatly limited, and the arrangement tends to be orderly. The boiling point is relatively high, about 180-190 ° C. When the temperature rises to the boiling point, the molecules gain enough energy to break free from each other's forces and transform from liquid to gas. < Br >
Its density is also one of the key physical properties, about 1.25 g/cm ³, which is slightly higher than the density of water. Therefore, when placed in water, this substance will sink to the bottom. In terms of solubility, 3-pyridylamine, pseudo- (trifluoromethyl) -has good solubility in common organic solvents such as ethanol and ether. Because its molecular structure has similar chemical properties to organic solvents, it follows the principle of "similar miscibility". However, in water, it has only a certain solubility, which is mainly due to the hydrophobicity of its fluorine-containing groups. < Br >
In addition, its refractive index also has a specific value, about 1.44 - 1.46. This property is of great significance in the optical field or material identification, and can help to identify the purity and characteristics of this compound. In summary, the physical properties provide a foundation for the in-depth understanding and application of 3-pyridylamine, pseudo- (trifluoromethyl) -.

3-Pyridylmethylamine, pseudo- (trifluoromethyl) - The chemical properties of this substance are as follows:
It has a certain alkalinity. Because the molecule contains an amino group, the nitrogen atom of the amino group has a lone pair of electrons and can bind protons, it is alkaline. And the basicity may be reflected in the interaction between specific chemical reactions and substances. In the acid-base reaction system, it can be used as a base to participate in the reaction.
In terms of its nucleophilicity, the amino group is a nucleophilic group. Under suitable reaction conditions, it can attack the electrophilic reagent, triggering reactions such as nucleophilic substitution or addition. In case of halogenated hydrocarbons, amino nitrogen atoms or carbon atoms attacking halogenated hydrocarbons, the halogen atoms leave to form new nitrogen-containing compounds.
The part of the pyridine ring in its molecule gives the substance a unique electronic effect and spatial structure. The pyridine ring is aromatic, and the electron cloud distribution is special, or it affects the reactivity of the groups connected to it. And the electron cloud density distribution on the pyridine ring is uneven, and the carbon atom reactivity at different positions is different, or the reaction check point is selective in reactions such as electrophilic substitution.
In addition, the presence of trifluoromethyl greatly affects the physical and chemical properties of the compound. Trifluoromethyl has strong electron absorption, which can increase the polarity of the molecule and affect the solubility of the substance. Generally speaking, it will change the solubility of the substance in polar solvents. At the same time, strong electron absorption can reduce the electron cloud density of the carbon atoms connected to it, change the electron cloud distribution of the surrounding chemical bonds, affect the overall reactivity of the compound, and in some reactions, or cause changes in the reaction rate and product selectivity.
The chemical properties of this compound are complex and interrelated, and each group affects each other. In the fields of organic synthesis and other fields, various chemical reactions can be designed and realized according to their properties to prepare compounds with specific functions.

To prepare 3-pyridine methylamine, pseudo- (trifluoromethyl), the method is as follows:
Take the pyridine as the base first, and introduce the genus of methylamine into its three bits. This step is quite critical and relates to the structure of the product. To add methylamine groups to the three bits of pyridine, the method of nucleophilic substitution can be selected. Depending on the electron cloud distribution of the pyridine ring, the three bits of it are more electrophilic and can interact with the nucleophilic reagent methylamine. However, the stability of the pyridine ring is quite strong. In order to make the reaction smooth, a suitable catalyst is often required, and temperature control and time control are also indispensable The temperature control is related to the reaction rate and the purity of the product. It should be in a moderate range. If it is too high, side reactions will occur, and if it is too low, the reaction will be slow and difficult to achieve expectations for a long time.
As for the introduction of pseudo- (trifluoromethyl), it can be done after the methylamine group is implanted. This step also needs to be cautious when reacting with the obtained intermediate with a reagent containing trifluoromethyl. Trifluoromethyl has strong electron absorption, and its introduction will greatly change the physical and chemical properties of the compound. When reacting, the choice of solvent is also very important, which needs to be compatible with the reactants and reagents, and has the effect of promoting the reaction process At the same time, the pH of the reaction environment also needs to be adjusted to an appropriate value, because either peracid or peralkali can cause the reaction to be biased, resulting in a non-desired product.
During the entire synthesis process, each step of the reaction is related to each other, and the product of the previous step is the raw material of the next step. Each step requires precise operation, and detailed study of the reaction conditions, from the purity and dosage of the reagent to the control of temperature and time, cannot be ignored. In this way, it is expected to obtain the target product of 3-pyridylmethylamine and pseudo- (trifluoromethyl) in a higher yield.

I don't know the price range of 3-pyridylmethylamine, pseudo- (trifluoromethyl) in the market. However, the price of various things in the market often changes for various reasons, and it is difficult to hide it in a single word.
Its price may vary depending on the place of origin. In different places, the quality and quantity of this product are different, and the price is also different. If the product is rich, the supply is more and the price is flat; if the product is thin, the supply is more and the supply is less, the price is high.
The production process is also the main reason. If the process is difficult, time-consuming, and the material is used, the cost is high, and the price rises; if the process is simple, the cost decreases, and the price is also low.
The supply and demand situation of the city also affects its price. There are many people in need, and the demand exceeds the supply, and the price tends to rise; if the supply exceeds the demand, the merchant wants to sell quickly, and the price may fall.
There are brands, packaging, logistics, etc., which can make the price different. A well-known brand may have a high price due to its high reputation; the packaging is exquisite, which can increase its value; the distance of logistics is related to the amount of cost, and it is also related to the price.
To know the exact price, when visiting the chemical market, reagent suppliers, or checking online business platforms, in order to obtain the current detailed price.