3-Pyridinemethanamine, 6-chloro-

3-Pyridyl methylamine, 6-chlorine - The chemical properties of this substance are quite important. Its physical properties, whether solid at room temperature, look at its morphology, or crystalline, white or nearly white, with specific melting points and boiling points. However, these values still need to be determined by precise experiments.
In terms of its chemical activity, the presence of chlorine atoms in the molecule makes it have the characteristics of halogenated hydrocarbons. Chlorine atoms are more active and easily participate in substitution reactions. If they encounter nucleophiles, chlorine atoms can be replaced to form new compounds. The presence of pyridine rings imparts aromatic properties to the molecule, and the electron cloud distribution characteristics of nitrogen atoms on the pyridine ring make the reactivity of different positions on the ring different. The pyridine ring can participate in the electrophilic substitution reaction, and other groups can be introduced at specific positions under suitable conditions.
Its amino moiety is also active and can participate in many organic reactions. Amino groups can react with acids to form salts, or acylated with acyl halides, acid anhydrides, etc., to form amide compounds. The chemical properties of this compound are of great significance in the field of organic synthesis, or can be used as a key intermediate for the preparation of organic compounds with more complex structures, providing basic raw materials for new drug development, materials science and many other fields.

The physical properties of 3-pyridylmethylamine, 6-chlorine-this substance are of great importance for its application in many fields. Its appearance is often colorless to slightly yellow liquid, and it has a certain fluidity. Smell, or have a specific smell. Although this smell is not pungent and intolerable, it is also unique and can help to identify.
When it comes to density, under specific conditions, it has a fixed value, about [X] g/cm ³. This density value, compared with common organic solvents, may have similarities and differences, affecting its distribution and behavior in mixed systems. Its boiling point is also a key physical property. Under standard atmospheric pressure, the boiling point is roughly [X] ° C. This boiling point characteristic determines the choice of conditions during operations such as heating and separation.
Furthermore, in terms of solubility, it can be soluble in some organic solvents, such as ethanol and ether, etc., but its solubility in water is relatively limited. This difference in solubility is due to its molecular structure characteristics. The existence of pyridine rings and chlorine atoms affects the interaction between molecules and different solvent molecules.
In addition, the melting point is also a physical property to be considered. Its melting point is about [X] ° C. This melting point value is of great significance in the crystallization and storage of substances. These many physical properties, interrelated, together determine the performance and application of 3-pyridylmethylamine and 6-chlorine in various scenarios.

3-Pyridylmethylamine, 6-chlorine - This substance has a wide range of uses. In the field of medicine, it is often the key raw material for the synthesis of special drugs. Because of its unique chemical structure, it endows the drug with specific activity and curative effect, and can play a significant therapeutic effect on specific diseases.
In the field of materials science, it also has extraordinary functions. It can be used as a basic material for the construction of special performance materials. Through clever chemical reactions, materials with unique physical and chemical properties can be shaped, such as optimizing the stability and conductivity of materials, etc., to meet the strict needs of many fields for special materials.
In the process of scientific research and exploration, this compound is often used as an important reagent. Scientists rely on their participation in various reactions, in-depth exploration of chemical mechanisms, revealing the mysteries of interactions between substances, contributing to the expansion and deepening of chemical theory, and then promoting the vigorous development of related disciplines. In short, 3-pyridylmethylamine, 6-chlorine - play an indispensable role in many key fields and have a profound impact on scientific and technological progress and social development.

To prepare 6-chloro-3-pyridylmethylamine, you can follow the following ancient method. First take 3-chloropyridine, which is the starting material. It is co-placed with paraformaldehyde and hydrochloric acid in a suitable reaction vessel and reacted at an appropriate temperature. This step aims to introduce hydroxymethyl into the 3-position of pyridine. Pay attention to the control of the reaction temperature and time. If the temperature is too high or the time is too long, the side reaction may occur. After the reaction is completed, 3 - (chloromethyl) pyridine hydrochloride is obtained by conventional operations such as cooling and separation.
Then, take the obtained 3- (chloromethyl) pyridine hydrochloride and react with sodium cyanide or potassium cyanide in a suitable solvent. This step is nucleophilic substitution, replacing the chlorine atom of chloromethyl with cyanyl to generate 3- (cyanomethyl) pyridine. This reaction needs to be carried out under mild conditions, and the proportion of reactants and the reaction process must be strictly controlled. Due to the toxicity of cyanide, the operation must be cautious.
Then 3- (cyanomethyl) pyridine is reduced in an anhydrous organic solvent with a suitable reducing agent, such as lithium aluminum hydride. This reduction step can convert cyano group into methylamino group, then obtain the target product 6-chloro-3-pyridylmethylamine. After the reaction is completed, a series of operations such as hydrolysis and purification are carried out to obtain a pure product. During the whole synthesis process, each step of the reaction needs to carefully control the conditions and strictly abide by the operating procedures to obtain the ideal yield and purity.

I don't know the price range of 3 - Pyridinemethanamine, 6 - chloro - in the market. This is a more specialized chemical substance, and its price often varies due to many factors.
First, purity has a great impact. If the purity is extremely high, it is suitable for high-end scientific research or specific industrial uses, and the price must be high; if the purity is slightly lower, it is used for general experiments or production that is not demanding, and the price may be slightly lower.
Second, the market supply and demand relationship is also critical. If there are many people who want it, and the supply is limited, if there is a large demand in a specific industry, or the supply is reduced due to production difficulties, the price will rise; conversely, if the demand is weak and the supply is sufficient, the price may stabilize or even decline.
Third, the production process is closely related to the cost. If the preparation of this substance requires complex processes, expensive raw materials or harsh conditions, the cost will be high, and the price will also be high; if the process is simple and the raw materials are easily available, the price may be relatively close to the people.
Fourth, the sales channels are different, and the prices are also different. Purchased directly from the manufacturer, or the price is advantageous due to less intermediate links; through multi-level dealers, the price may increase due to many intermediate costs.
Because I do not know the details of the current market, it is difficult to determine its price range. If you want to know the details, you can consult chemical reagent suppliers, relevant chemical trading platforms, or inquire in the industry to get more accurate price information.