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What are the main uses of 3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI)?
3 - Pyridinecarboxylic acid, 2,6 - difluoro - (9CI) is 2,6 - difluoronicotinic acid, which is widely used.
In the field of medicine, it is a key pharmaceutical intermediate. A variety of compounds with specific biological activities can be synthesized through a series of chemical transformations. Some of these compounds may have antibacterial properties, which can effectively inhibit the growth and reproduction of bacteria, which is very helpful in combating diseases caused by bacteria; some may exhibit antiviral effects and help fight viral infections. For example, some drugs based on the synthesis of 2,6 - difluoronicotinic acid have shown good potential for the treatment of specific viral infections in clinical trials.
In the field of pesticides, 2,6-difluoronicotinic acid also occupies an important position. Using it as raw materials, a variety of high-efficiency pesticides can be prepared. Some pesticides have high selective killing ability on crop pests and can precisely attack pests, while they have little impact on crops themselves, which helps to improve crop yield and quality. Some can be used as plant growth regulators to regulate plant growth processes, such as promoting plant root development, making plant roots more developed, enhancing plant absorption of nutrients and water; or regulating plant flowering and fruiting process, improving fruit quality and yield.
In the field of materials science, 2,6-difluoronicotinic acid also has its uses. Can participate in the synthesis of functional materials. For example, by reacting with specific organic or inorganic compounds, materials with special optical, electrical, or thermal properties can be prepared. Such materials can be used in electronic devices, such as making better semiconductor materials to improve the performance and stability of electronic devices; or in the field of optics, making materials with unique optical properties, used in optical instruments or display devices.
What are the physical properties of 3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI)
3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI), the physical properties of this substance are related to many aspects of its external characterization and physical properties.
Looking at its properties, under normal temperature, or white to off-white crystalline powders, this form is common in many organic compounds, and the state of the powder is conducive to its operation and processing in various experiments and production links. Its melting point, determined under specific conditions, is about a certain temperature range. This temperature range is the critical interval for the compound to change from solid to liquid. The determination of the melting point is of great significance for the identification and purification of the substance. The melting point of the compound with different purity may be slightly different, which is also an important basis for judging the purity.
Re-discuss its solubility, in common organic solvents, or show unique solubility characteristics. In organic solvents such as ethanol and acetone, or with a certain solubility, this property makes it possible to separate, purify and participate in specific chemical reactions according to the principle of solubility in organic synthesis, drug research and development, etc. In water, its solubility may be relatively low, which is related to the functional groups contained in the molecular structure and the electronegativity of fluorine atoms. The introduction of fluorine atoms enhances the hydrophobicity of molecules, thus reducing the degree of solubility in water. < Br >
Its density is also one of the important physical properties. Determined by specific experimental methods, this value reflects the mass per unit volume of the substance, and provides key data support for the measurement, mixing and reaction system design of materials in chemical production. In addition, the stability of the compound is relatively stable under general environmental conditions, but in case of extreme conditions such as high temperature, strong acid and strong alkali, the molecular structure may change. Understanding this stability helps to ensure its quality and performance during storage and use.
The above physical properties are interrelated and useful, and are indispensable basic information in many fields such as organic chemistry research, drug development, and chemical production, helping researchers and producers to better grasp the properties and applications of the compound.
What are the chemical synthesis methods of 3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI)
There are various ways to synthesize 3-pyridinecarboxylic acid, 2,6-difluoro- (9CI). One is to use pyridine as the starting material and introduce fluorine atoms by halogenation. First, with an appropriate halogenation reagent and under suitable reaction conditions, a halogenation reaction occurs at the 2,6 positions of pyridine to introduce halogen atoms. Subsequent reactions such as nucleophilic substitution, the halogen atom is replaced by a fluorine atom, and the fluorine-substituted structure in the target product is obtained. Finally, through carboxylation, a carboxyl group is introduced at the 3 position of pyridine to form a 3-pyridinecarboxylic acid and a 2,6-difluoro compound. < Br >
Second, starting from the pyridine derivative containing carboxyl groups, the carboxyl groups are properly protected first, and then the pyridine ring is halogenated to introduce fluorine atoms. After the fluorine atoms are successfully introduced into the designated position, the protective groups of the carboxyl groups are removed to obtain this compound.
Or it can be achieved by a metal-catalyzed coupling reaction. Select suitable fluorine-containing aryl halides and pyridine-containing boric acids or boric acid esters, and in the presence of a metal catalyst, a coupling reaction occurs to construct a fluorine-substituted structure on the pyridine ring, and then the carboxyl groups are introduced through subsequent reactions to complete the synthesis of 3-pyridinecarboxylic acid, 2,6-difluoro- (9CI).
This number method has its own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider various factors such as the availability of raw materials, the difficulty of reaction conditions, and the cost, and choose the optimal method.
What is the price range of 3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI) in the market?
I have not heard of the exact price range of "3 - Pyridinecarboxylic acid, 2,6 - difluoro - (9CI) " in the market. This is the expression of a chemical substance, and its market price often varies due to multiple factors.
First, the purity has a great impact. If the purity is very high, it is suitable for high-end scientific research, pharmaceutical and other precision fields, and the price must be high; if the purity is slightly lower, it is mostly used for general industrial use, and the price may be relatively low.
Second, the supply and demand relationship is the key factor. If the market demand for this product is strong, but the supply is limited, in case of a surge in demand due to the rapid development of a specific industry, or a shortage of supply due to the production process, the price will rise; conversely, if the demand is weak and the supply is sufficient, the price may decline.
Third, the complexity of the production process also plays a role. If the synthesis of this substance requires cumbersome steps, special raw materials or harsh conditions, the production cost will increase, and the price will also rise.
Fourth, sales channels and regions also have an impact on the price. Purchased through regular large suppliers, the price may be relatively stable and high; purchased from small dealers, or have different prices due to cost differences. Prices will also vary in different regions due to differences in economic level, transportation costs, etc.
To sum up, in order to know the exact price range of this product, it is necessary to check the chemical product trading platform in detail, consult relevant suppliers and industry professionals, and obtain accurate information.
What are the storage conditions for 3-Pyridinecarboxylic acid, 2,6-difluoro- (9CI)?
2-6-Difluoro-3-pyridinecarboxylic acid (9CI), this is a chemical substance. Its storage conditions are very critical, which is related to the stability and quality of the substance.
This substance should be stored in a cool and dry place. In a cool environment, it can avoid changes in its properties caused by high temperature. Due to high temperature, it is easy to cause chemical reactions, or cause structural changes and quality damage. In a dry place, it can prevent moisture intrusion. If the moisture is heavy, or it causes reactions such as hydrolysis, it will affect the purity and performance.
Furthermore, it needs to be placed in a well-ventilated place. Good ventilation can disperse harmful gases that may be generated, avoid their accumulation, and reduce safety risks. At the same time, it should be placed separately from oxidizing agents, reducing agents and other chemicals. Dangerous due to the interaction or violent reaction of different chemical substances.
The container in which the substance is stored must be well sealed. The seal can prevent air and moisture from entering, and ensure the purity and stability of the substance. When choosing the container, according to the characteristics of the substance, such as corrosiveness, etc., choose the suitable material to prevent the container from being corroded and leaking.
The storage area should be clearly marked, indicating the name, characteristics and precautions of the substance. This is convenient for personnel to identify. In case of emergency, they can quickly take correct measures to ensure storage safety and maintain the quality of the substance for subsequent use.