3 Pyridinecarboxylic Acid 6 Chloro Methyl Ester
pyridine pyrrole pyrazine piperidine piperazine

3-Pyridinecarboxylic acid, 6-chloro-, methyl ester

    Specifications

    HS Code

    262365

    Name 6-Chloro-3-pyridinecarboxylic acid methyl ester
    Chemical Formula C7H6ClNO2
    Molar Mass 171.58 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point Data may vary, needs experimental determination
    Boiling Point Data may vary, needs experimental determination
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Data may vary, needs experimental determination
    Pka Data may vary, needs experimental determination
    Flash Point Data may vary, needs experimental determination
    Odor Typically has a characteristic organic odor

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    General Information
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    Frequently Asked Questions

    As a leading 3-Pyridinecarboxylic acid, 6-chloro-, methyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of methyl 6-chloro-3-pyridinecarboxylate?
    What are the main uses of mercury-3-alkyl mercury? Mercury and its compounds have a wide range of uses and are used in many fields such as industry, agriculture, medicine, etc. Among alkyl mercury, methylmercury is particularly typical.
    In the past, alkyl mercury was often used as a fungicide in the agricultural field. Because of its strong bactericidal ability, it can effectively inhibit the growth of crop diseases and insect pests, protect crop growth, and increase yield. For example, in some rice planting areas, alkyl mercury fungicides have been used to treat seeds and soil, hoping to prevent and control rice seedling diseases and other diseases.
    However, alkyl mercury is very toxic, and its harm to the environment and human health has become increasingly recognized over time. Alkyl mercury easily accumulates in the environment, accumulates through the food chain, and eventually endangers humans. It can damage the human nervous system, immune system, etc., and has a particular impact on the development of fetuses and children, causing serious consequences such as mental retardation and developmental delay.
    Nowadays, in view of its great harm, most countries have strictly restricted or even banned the use of alkyl mercury. In the past, alkyl mercury fungicides used in agriculture were rare, and they were replaced by safer and more environmentally friendly bactericidal methods and agents. Although alkyl mercury used to play a certain role in agricultural disease prevention and production in the past, its serious harm far exceeded its benefits, so it was eliminated to protect the ecological environment and human health.
    What are the synthesis methods of methyl 6-chloro-3-pyridyl carboxylate?
    To prepare ethyl 3-pentenoate, there are three methods.
    First, diethyl malonate is used as the starting point. First, when diethyl malonate meets sodium alcohol, the methylene hydrogen of diethyl malonate is replaced by sodium to form a carbonated ion. Afterwards, the carbonated ion is nucleophilically substituted with 1-bromopropene, and the allyl is attached to the methylene. Then, the ester group is hydrolyzed in alkali solution to form a malonic acid derivative. Next, the decarboxylation is heated to obtain 3-pentenoic acid. Finally, 3-pentenoic acid is esterified with ethanol under the catalysis of concentrated sulfuric acid to obtain ethyl 3-pentenoate. Although this process is a little complicated, the raw materials are common and the reaction conditions are easy to control.
    Second, ethyl acetoacetate is used as the group. Ethyl acetoacetate first interacts with sodium ethanol, and its methylene hydrogen is replaced by sodium. Later, it is nucleophilic substituted with 1-bromopropylene, and the allyl is added to methylene. Then, the ester group is alkali-hydrolyzed, and then acidified to obtain β-ketoacid. Heat decarboxylation, β-carbonyl cracking, to obtain 3-pentenoic acid. Finally, 3-pentenoic acid and ethanol are esterified by concentrated sulfuric acid to obtain the target product. This method also uses common raw materials, and the reaction operation is feasible. < Br >
    Third, ethyl acrylate and ethylene are used as materials, and under the action of transition metal catalysts, the olefin is prepared by metathesis reaction. This reaction has the advantages of high atomic economy, mild conditions, and easy separation of products. However, the price of transition metal catalysts is high, and the cost may increase.
    These three production methods have their own advantages and disadvantages. The actual preparation needs to be based on the comprehensive consideration of raw material availability, cost, yield, etc., and the optimal method is selected.
    What are the physical properties of methyl 6-chloro-3-pyridyl carboxylate
    Mercury, also known as mercury, has a special nature. At room temperature, mercury is liquid and has very good fluidity. It is like smart water and can roll freely on a plane, just like a round bead. This property is different from many common metals, most of which are solid, only mercury is liquid and unique among metals.
    Mercury has a high density, which is heavier than common water. If mercury is placed in water, it immediately sinks to the bottom of the water, which shows that its density is much higher than that of water. And mercury is not easy to evaporate, and in general environments, its vapor is emitted very slowly. However, it should be noted that mercury vapor is toxic, and even if inhaled in small amounts, it may cause damage to human health.
    Ethyl acrylate is a colorless and transparent liquid with a fragrant smell. The boiling point of ethyl acrylate is relatively low, and it is easy to evaporate into a gas at an appropriate temperature. Its volatility makes it necessary to be properly controlled in some industrial scenarios to prevent gas accumulation from causing safety hazards.
    Furthermore, ethyl acrylate can be soluble with many organic solvents, showing good solubility. In the field of chemical production, this property makes ethyl acrylate an excellent solvent or reaction medium to participate in many chemical reactions. However, ethyl acrylate has a certain degree of irritation. If it comes into contact with human skin or eyes, it may cause discomfort, severe or injury.
    In conclusion, the physical properties of mercury and ethyl acrylate are unique, and in practical application and operation, it is necessary to fully understand and follow the corresponding safety procedures to prevent the occurrence of hazards.
    What are the chemical properties of methyl 6-chloro-3-pyridyl carboxylate
    Mercury is a highly toxic substance. It is active and can evaporate into mercury vapor at room temperature. If inhaled into the human body, it can cause damage to the organs, especially the liver and kidneys.
    Trimethyl monochlorosilane has special chemical properties. First, it is very easy to hydrolyze, and it reacts rapidly in contact with water to form hydrochloric acid and hexamethyldisiloxane. This hydrolysis process is very violent and often accompanied by fever. Second, it is extremely flammable. In case of open flames or hot topics, it will be like dry wood in case of fire, instantly igniting a raging flame, and even triggering the danger of explosion. The vapor mixes with air to form an explosive mixture. Third, it is corrosive. It has a strong irritating and corrosive effect on human skin, eyes, respiratory mucosa, etc., and careless contact will cause serious burns. Fourth, it is chemically active and easy to react with many substances to form different compounds.
    When using these two, be sure to be extremely cautious, strictly abide by the operating procedures, and take protective measures to prevent accidents from happening, endangering life safety and the environment.
    What is the price range of methyl 6-chloro-3-pyridyl carboxylate in the market?
    What you are asking is about the price range of cuprous cyanide in the market. Cuprous cyanide is also a chemical substance. It is widely used in electroplating, medicine, pigments and other industries.
    However, its price often changes due to many factors. The first one is the price of raw materials. The production of cuprous cyanide requires raw materials such as copper salts and cyanide. If the price of such raw materials fluctuates, the price of cuprous cyanide will also be affected. Furthermore, the relationship between supply and demand in the market is also crucial. If the market has strong demand for cuprous cyanide and limited supply, the price will rise; conversely, if the supply exceeds demand, the price will decline. In addition, the pros and cons of the production process, the constraints of policies and regulations, etc., can all affect the price.
    According to the current market conditions, the price of cuprous cyanide per kilogram ranges from tens to hundreds of yuan. However, this is only a rough range, and the actual price depends on the specific quality, purity, trading time and market dynamics. If you want to know the exact price, you can consult the chemical product trading platform, relevant manufacturers or distributors, who can give you more detailed information.