3-Pyridinecarboxylic acid, 6-((3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl)-, ethyl ester

This is the chemical substance of 3-pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl) ethynyl) -, ethyl ester. To clarify its chemical structure, it is necessary to analyze it according to the rules of organic chemistry and nomenclature.
This compound belongs to the ester class, and its name is derived from the ester formed by the corresponding acid and alcohol. "3-pyridinecarboxylic acid" indicates the acid part. The pyridine ring is a six-membered nitrogen-containing heterocycle with a carboxyl group at the 3 position. " 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl) ethynyl) - "indicates that the 6-position of the pyridine ring has a specific substituent. This substituent is connected by ethynyl with 3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl. A heterocyclic sulphur atom of 3,4-dihydro-4,4-dimethyl-2H-1-benzothian, hydrogenated at positions 3 and 4, with two methyl groups at position 4. "Ethyl" indicates that the ester is formed from ethanol and the corresponding acid, that is, the carboxyl group is dehydrated and condensed with the hydroxyl group of ethanol.
Its chemical structure is roughly as follows: the pyridine ring is the core, and the 6-position is connected with ethynyl group to 3,4-dihydro-4,4-dimethyl-2H-1-benzothian-6-yl, and the 3-position carboxyl group of the pyridine ring is estered with ethanol. Such a structure may have specific activities and uses in the fields of organic synthesis and medicinal chemistry, and may exhibit unique chemical properties due to the characteristics of each part of the structure.

3-Pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl) ethynyl) -, ethyl ester The physical properties of this substance are as follows.
From the perspective of normal temperature, it may be a solid at room temperature, because its structure contains polycyclic and ester groups, ethynyl groups, etc., and the intermolecular force is large, which may cause its aggregation state to be a solid state. Its color may be white to light yellow, because although the structure of such organic compounds contains conjugated systems, the degree does not reach the state of significant color generation, so the color is lighter. < Br >
Smell it, or have a weak special smell. The existence of ester groups makes it have a fruit-like aroma or a special organic smell. However, due to the influence of other groups in the molecule, the smell may not be strong and pungent.
Check its solubility. Because it contains ester groups, it is a lipophilic group. It may have a certain solubility in common organic solvents such as ethanol, ether, chloroform, etc. However, the existence of pyridine rings makes it have a certain polarity. It may be slightly soluble in water. Overall, it is more soluble in organic solvents.
On its melting point, due to its complex structure, orderly arrangement of molecules, strong interaction, and high melting point. The specific value, when determined according to accurate experiments, can be inferred to be in a certain temperature range, which may be similar to similar compounds containing polycyclic and ester-based structures.
Its density is also closely related to the structure, the atoms in the molecule are closely arranged, the relative molecular mass is large, and the density may be greater than that of water, which is within the common density range of organic compounds.
The physical properties of this substance are determined by its unique molecular structure, and the groups interact with each other to create the above characteristics.

This is a compound of 3-pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl) ethynyl) -, ethyl ester. It has a wide range of uses and is often used in the field of medicinal chemistry.
In the process of drug development, this compound may have unique pharmacological activities, which can lay the foundation for the creation of new drugs. Its structural properties may interact with specific biological targets, just like a delicate key matching a precise keyhole, which in turn has a regulating effect on physiological processes in vivo. Or can participate in the research and development of therapeutic drugs for specific diseases, such as for some inflammation-related diseases, with its structure and activity characteristics, it may inhibit the release of inflammatory mediators, regulate the immune response, and achieve the purpose of alleviating inflammation; in the field of cardiovascular diseases, it may affect the function of vascular endothelial cells, blood lipid metabolism, etc., to help prevent and treat cardiovascular diseases.
In the field of organic synthesis, it is also an important intermediate. With its own special structure, it can participate in the construction of various complex organic molecules. Chemists can use ingenious chemical reactions to use it as a starting material to perform functional group transformation, carbon chain extension and other operations, just like building delicate molecular building blocks, to construct more organic compounds with novel structures and unique functions, which will contribute to the development of organic synthetic chemistry. Its importance in the field of medicinal chemistry is like the cornerstone of a tall building, providing indispensable support for the continuous progress of related fields.

To prepare 3-pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl) ethynyl) -, ethyl ester, there are various methods for synthesizing it.
First, it can be prepared from pyridine derivatives with corresponding substituents and ethylene derivatives containing 3,4-dihydro-4,4-dimethyl-2H-1-benzothiano-6-yl, under the action of appropriate catalysts, through coupling reaction. First take the pyridinecarboxylic acid derivative, the 6-position of the pyridine ring needs to have a substituted group, and the 3-position is a carboxyl group. This carboxyl group can be esterified and converted into the form of ethyl ester to prevent it from interfering in subsequent reactions. Then prepare acetylene derivatives containing specific benzoxanide structures, place them in the reaction system, and select a palladium-based catalyst to catalyze the coupling of the two at a suitable reaction temperature and solvent environment, so that the acetylene group is connected to the 6-position of the pyridine ring, so as to obtain the target product.
Second, you can also start with the construction of benzoxanide rings. First, the intermediates with the potential structural fragments of ethynyl and ethyl pyridinate are synthesized through a series of reactions with suitable raw materials. For example, appropriate thiophenols and olefin compounds are selected to form benzoxianran rings through cyclization, and functional groups that can be further converted to ethynyl groups are introduced at the 6th position. Subsequent functional group conversion is performed to generate a benzoxianan structure containing ethynyl groups, and then ligation reactions are carried out with pyridine derivatives to obtain the target product. This process requires fine regulation of the reaction conditions at each step to ensure that the reaction proceeds according to the designed path and avoids side reactions.
Third, a step-by-step construction strategy can also be considered. First, ethyl pyridinecarboxylate and a fragment containing benzothian structure with active functional groups were synthesized, and then the two were spliced through selective reactions. For example, ethyl pyridinecarboxylate was synthesized first, and then 3,4-dihydro-4,4-dimethyl-2H-1-benzothian-6-position compounds with halogen atoms or other active groups prone to nucleophilic substitution reactions were prepared by a specific method. Subsequently, by nucleophilic substitution reaction, the benzothian fragment was connected to ethyl pyridinecarboxylate, and the target 3-pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothian-6-yl) ethynyl) -, ethyl ester was finally prepared.

I look at your inquiry, is 3-pyridinecarboxylic acid, 6- ((3,4-dihydro-4,4-dimethyl-2H-1-benzothian-6-yl) ethynyl) -, ethyl ester in the market price. However, the price of this product is difficult to determine.
The market is unpredictable, and its price often varies due to many reasons. First, the production is different, and the price may vary. If the place of production is abundant in resources and convenient to harvest, the price may be slightly cheaper; if the place of production is remote, the harvest is difficult, and the price may increase. Second, the quality is also related to the price. If the quality is high, the price is not low; if the quality is normal, the price may drop. Third, the trend of supply and demand is the main factor affecting the price. If there are many people in the market who want it, but there are few people who supply it, the price will rise; on the contrary, if the supply exceeds the demand, the price will fall.
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