3 Pyridinecarboxylic Acid 5 Hydroxy
pyridine pyrrole pyrazine piperidine piperazine

3-PYRIDINECARBOXYLIC ACID, 5-HYDROXY-

    Specifications

    HS Code

    196245

    Chemical Formula C6H5NO3
    Molar Mass 139.11 g/mol
    Appearance Solid

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    Frequently Asked Questions

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    3-PYRIDINECARBOXYLIC ACID, what is the main use of 5-HYDROXY-
    3-Pyridyl carboxylic acid, 5-hydroxy group - This substance has a wide range of uses. In the field of medicine, it can be a key raw material for the synthesis of important drugs. Due to its unique chemical structure, it can participate in the construction of many drug molecules. After specific chemical reactions, it can be cleverly combined with other compounds to form drugs with specific pharmacological activities, or it can be used for the treatment of diseases, such as certain inflammation or chronic diseases. It may be effective.
    In the chemical industry, it also cannot be ignored. It can be used as an intermediate in organic synthesis to help synthesize a variety of high-value-added fine chemicals. After a series of complex chemical transformations, excellent material additives can be derived, such as additives used to improve material stability and enhance certain properties of materials, which are of great significance to improving material quality.
    It also plays an important role in scientific research and exploration. Researchers often use it as a starting material to conduct in-depth chemical research, explore new chemical reaction paths, develop novel synthesis methods, and contribute to the development of chemical science. Because its special structure contains many potential reactions, it can open up new ideas for scientific research and promote the continuous development of the chemical field.
    3-PYRIDINECARBOXYLIC the physical properties of ACID, 5-HYDROXY-
    3-Pyridinecarboxylic acid, 5-hydroxy-, this is an organic compound. Its physical properties are particularly important and are relevant to many applications in chemistry and related fields.
    First of all, its appearance is often white to light yellow crystalline powder, with a fine texture, similar to the micro-powder of nature. This appearance characteristic is quite critical when identifying and preliminarily understanding the compound.
    Furthermore, when it comes to the melting point, it is about a specific temperature range, and this value is an important physical indicator of the substance. Determination of the melting point can help chemists determine its purity and crystal structure characteristics. When heated to a specific temperature, the compound gradually melts from the solid state to the liquid state. The temperature limit of this transition accurately reflects the strength of the intermolecular forces.
    Solubility is also one of the key physical properties. In water, its solubility may be limited, but in some organic solvents, it exhibits good solubility. For example, in organic solvents such as ethanol and acetone, it can be moderately dissolved. This property provides a basis for operation in the process of chemical synthesis and separation and purification. With its difference in solubility, it can be effectively separated and purified from other substances.
    In addition, the density of the compound also has a specific value, which reflects its mass per unit volume. The determination of density helps to accurately control its dosage and occupied space in practical applications, which is of great significance in chemical production and experimental operations.
    And looking at its stability, it has a certain stability under normal conditions of room temperature and pressure. In case of extreme environments such as high temperature, strong acid, and strong alkali, or chemical reactions occur, resulting in changes in its structure and properties. The characteristics of this stability are important factors to consider when storing and using the compound. It needs to be properly stored to avoid the influence of external factors and ensure the stability of its properties, so that it can play the expected effect in subsequent applications.
    3-PYRIDINECARBOXYLIC the chemical properties of ACID, 5-HYDROXY-
    3-Pyridinecarboxylic acid, 5-hydroxy-, this is an organic compound. Its chemical properties are unique and acidic. Because it contains carboxyl groups, it can release hydrogen ions under suitable conditions, neutralize with bases, and generate corresponding salts and water.
    From a structural point of view, the pyridine ring endows it with certain stability and aromaticity. And the 5-position hydroxyl group adds many reactive activities. The hydroxyl group can participate in the esterification reaction and interact with the acid to form ester compounds. This process requires suitable catalysts and reaction conditions.
    At the same time, the hydroxyl group has nucleophilic properties and can react with electrophilic reagents. Under oxidation conditions, hydroxyl groups can be oxidized to form different oxidation products such as aldehyde groups and carboxyl groups, which vary according to the specific oxidation reagents and reaction conditions.
    Furthermore, the nitrogen atom on the pyridine ring has a lone pair of electrons, which makes the compound alkaline to a certain extent and can form salts with acids. This property makes it potentially useful in organic synthesis, pharmaceutical chemistry and other fields. It can be used as an intermediate in organic synthesis to construct more complex compound structures; in drug development, or because of its unique chemical properties and biological activities, it has become a potential lead compound, laying the foundation for the creation of new drugs.
    What is the production method of 3-PYRIDINECARBOXYLIC ACID, 5-HYDROXY-
    The method of preparing 5-hydroxy-3-pyridine carboxylic acids is not detailed in ancient books, but according to today's chemical methods, various routes can be obtained.
    First, it can be started from a pyridine derivative. With a suitable pyridine compound, under specific reaction conditions, hydroxyl and carboxyl groups are introduced. For example, select a suitable substituted pyridine, introduce a halogen atom at a specific position in the pyridine ring by means of a halogenation reaction, and then through a nucleophilic substitution reaction, replace the halogen with a hydroxyl-containing reagent, and then convert the specific group into a carboxyl group through a suitable oxidation reaction. In this process, the control of reaction conditions is extremely critical, such as reaction temperature, reaction time, concentration and ratio of reagents used, etc., which can affect the yield and purity of the product.
    Second, it can be derived from natural products or compounds with similar structures. Find natural products containing pyridine structure or can be converted into pyridine structure, and undergo a series of chemical modifications to achieve the purpose of generating 5-hydroxy-3-pyridine carboxylic acid. Natural products come from a wide range of sources, but their separation and transformation require fine operation and suitable reaction conditions. For example, certain plant extracts or microbial metabolites, with appropriate treatment, can be used as starting materials.
    Third, the reaction catalyzed by transition metals. Transition metal catalysts are very effective in organic synthesis and can promote the formation of carbon-carbon bonds and carbon-heteroatomic bonds. In the preparation of this compound, transition metal catalysis can be used to realize hydroxylation and carboxylation of pyridine rings. Such methods often require the selection of suitable transition metal catalysts, such as palladium, copper, etc., and corresponding ligands to improve the selectivity and activity of the reaction.
    There are various methods for preparing 5-hydroxy-3-pyridinecarboxylic acids, and each method has its own advantages and disadvantages. According to actual needs, factors such as the availability of raw materials, the difficulty of reaction, the purity and yield of the product should be weighed to choose the appropriate method.
    3-PYRIDINECARBOXYLIC ACID, 5-HYDROXY - What is the price range in the market?
    I don't know the price range of 3-pyridyl carboxylic acid and 5-hydroxy in the market. However, the price of things in the market often changes due to many reasons. First, the price varies depending on the place of production. If the product is easy and abundant, the price of land near the source may be low; if the product is difficult and rare, the price must be high. Second, the quality is also related to the price. Those with excellent quality are often expensive; those with inferior quality are often cheap. Third, the supply and demand conditions of the market greatly affect the price. If there are many people who want it, those who supply it will be few, and the price will increase; if the supply exceeds the demand, the price will be reduced. Fourth, the seller's price is also different. In order to make a profit, each seller may refer to his own cost and hope for profit when pricing, resulting in different prices for the same product. If you want to determine the price of this 3-pyridyl carboxylic acid and 5-hydroxy product, you should consult various pharmaceutical stores, chemical stores, or various e-commerce platforms to observe the price state and comprehensively compare it to know the approximate price range.