3 Pyridinecarboxylic Acid 4 Chloro Methyl Ester
pyridine pyrrole pyrazine piperidine piperazine

3-pyridinecarboxylic acid, 4-chloro-, methyl ester

    Specifications

    HS Code

    926017

    Chemical Formula C7H6ClNO2
    Molecular Weight 171.58
    Appearance Solid (predicted)
    Boiling Point 264.2°C at 760 mmHg (predicted)
    Melting Point N/A
    Density 1.349 g/cm³ (predicted)
    Flash Point 113.6°C (predicted)
    Solubility In Water Insoluble (predicted)
    Logp 2.07 (predicted)
    Vapor Pressure 0.00475 mmHg at 25°C (predicted)

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    Frequently Asked Questions

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    What is the chemical structure of 3-pyridinecarboxylic acid, 4-chloro-, methyl ester?
    3 - to its carboxylic acid, this expression seems to refer to the conversion of a substance to a carboxylic acid or related properties. 4 - cyano-, methylnitrile, methylnitrile is acetonitrile, and its chemical structure is\ (CH_ {3} CN\). In the acetonitrile molecule, the carbon atom is connected to the nitrogen atom by a triple bond, and the methyl group\ ((- CH_ {3}) \) is connected to the nitrogen-containing cyanide group\ ((-CN) \). Structurally, it is a compound formed by a methyl group replacing the hydrogen atom in the hydrogen cyanic acid\ ((HCN) \). In its spatial structure, the central carbon atom is hybridized by\ (sp\), so that the cyanyl group has a linear structure, while the carbon atom of the methyl group is hybridized by\ (sp ^ {3}\). The overall acetonitrile molecule is not completely symmetric due to the connection between the methyl group and the cyanyl group. Acetonitrile is widely used in the field of organic synthesis because it has a certain polarity and can dissolve a variety of organic compounds. It is often used as an excellent organic solvent. In some reactions, the cyanyl group can undergo various transformations, such as hydrolysis to form carboxylic acids, reduction to form amine compounds, etc. These properties are closely related to its chemical structure.
    What are the main uses of 3-pyridinecarboxylic acid, 4-chloro-, and methyl ester?
    3 - to its carboxylic acid, this expression is relatively simple and vague, speculating or referring to the process of converting a substance into a corresponding carboxylic acid. However, the specific substance is not known, and it is difficult to describe its conversion path and mechanism in detail. Common alcohols can be gradually converted into carboxylic acids by oxidation reaction under the action of suitable oxidants. Take ethanol as an example. Under the action of strong oxidants such as acidic potassium dichromate, it is first oxidized to acetaldehyde, and further oxidized to obtain acetic acid.
    4 - halo-, methyl ether Main uses. Halogens are widely used. In the field of organic synthesis, they are often used as intermediates to construct carbon-carbon bonds, carbon-heteroatomic bonds, etc. For example, bromoethane can react with magnesium to form Grignard reagents, which can react with carbonyl compounds to grow carbon chains and be used to synthesize complex organic molecules. In medicinal chemistry, there are many halogen-containing drugs, such as fluoroquinolones. The introduction of halogen atoms can change the physicochemical properties and biological activities of drugs.
    Methyl ether often acts as a protective group in organic synthesis to protect easily reactive groups such as hydroxyl groups. When there are multiple active check points in the molecule, when a certain hydroxyl group needs to be selectively reacted, it can be converted into methyl ether for protection. After other reactions are completed, the protective group can be removed to restore the hydroxyl group. In addition, methyl ether is also used to prepare fragrances, such as some terpenoid methyl ether derivatives with special aroma, which can add product aroma. In the field of solvents, some methyl ether compounds can be used as solvents due to their suitable solubility and volatility, such as ethylene glycol dimethyl ether, which can dissolve a variety of organometallic compounds and is often used as solvents for organic synthesis reactions.
    What are the physical properties of 3-pyridinecarboxylic acid, 4-chloro-, methyl ester?
    3 - To its carboxylic acid, this is an important class of compounds in chemistry. Carboxylic acids are acidic because their carboxyl groups can partially ionize hydrogen ions. Their acidity is affected by many factors, such as the electronic effect with the carboxyl group. When the linked group is electron-absorbing, the acidity of the carboxyl group can be enhanced; if it is a supply group, the acidity is weakened. Carboxylic acids can neutralize with bases to form carboxylic salts and water, which is a common acid-base reaction. In addition, carboxylic acids can participate in esterification reactions, which react with alcohols under acid catalysis to form esters and water. This reaction is of great significance in organic synthesis, and is involved in the synthesis of many fragrances, drugs, etc.
    4 -alkanes are a class of saturated hydrocarbons. As the simplest alkane, methane has specific physical properties. It is a colorless and odorless gas at room temperature and pressure, extremely insoluble in water, and its density is lower than that of air. Due to the weak van der Waals force between alkanes, its melting boiling point is low, and it increases with the increase of the number of carbon atoms. The relative density of alkanes also increases with the increase of the number of carbon atoms, but it is less than water. In addition, alkanes are flammable and burn in sufficient oxygen to generate carbon dioxide and water. This property makes them an important energy substance. For example, the main component of natural gas is methane, which is widely used in life and industry.
    What are the preparation methods of 3-pyridinecarboxylic acid, 4-chloro-, and methyl ester?
    There are various preparation methods for 3-carboxyl, 4-alkan-, and methyl ethers, which are described in detail as follows:
    To prepare methyl ethers, one method can be to react alcohol and halomethane in an alkaline environment. Take alcohols, add an appropriate amount of bases, such as sodium hydroxide or potassium carbonate, to provide alkaline conditions, and then slowly add halomethane, such as chloromethane or bromomethane. In this reaction, the base will cause the alcohol to form alcohol negative ions, which have strong nucleophilicity and can attack the carbon atoms of halomethane. The halogen ions leave to form methyl ethers. This process requires attention to the reaction temperature and the ratio of reactants. If the temperature is too high or the ratio is out of balance, side reactions will easily occur. < Br >
    In the second method, phenolic compounds and dimethyl sulfate can also react in alkaline medium to obtain methyl ether. Phenol is weakly acidic, and phenol oxygen negative ions are formed under the action of alkali, and its nucleophilicity is good. Dimethyl sulfate is a commonly used methylation reagent. Phenol oxygen negative ions attack the methyl of dimethyl sulfate, and the sulfate ions leave to achieve the synthesis of methyl ether. During operation, due to the strong toxicity of dimethyl sulfate, careful protection must be taken and strict procedures must be followed.
    The Williamson synthesis method can also be used. React with halogenated hydrocarbons and sodium alcohol, which is prepared from alcohol and sodium metal or sodium hydride. Select suitable halogenated hydrocarbons, such as primary halogenated hydrocarbons, mix with sodium alcohols, and react in suitable solvents, such as anhydrous ethanol or dimethylformamide. During the reaction, the halogen atom of the halogenated hydrocarbons is replaced by the alkoxy group of sodium alcohols to obtain methyl ethers. The key to this method is the selection of halogenated hydrocarbons. Secondary halogenated hydrocarbons or tertiary halogenated hydrocarbons are prone to elimination reactions, which is not conducive to the formation of methyl ethers.
    The above methods have their own advantages and disadvantages. In practical application, it is necessary to carefully choose according to the availability of raw materials, reaction conditions, product purity and other factors to achieve the best preparation effect.
    What are the market prospects for 3-pyridinecarboxylic acid, 4-chloro-, methyl ester?
    What is the market prospect of 3-metacarboxylic acid, 4-bromo-, methyl ether?
    Fu3-metacarboxylic acid is widely used in the field of organic synthesis. It is often a key intermediate for the preparation of various fine chemicals. Looking at today's chemical industry, fine chemicals are developing rapidly, and the demand for high-purity and specific intermediates is increasing. This 3-metacarboxylic acid, with its unique chemical structure, has outstanding performance in the pharmaceutical, pesticide, fragrance and other industries. In the preparation of medicine, or can participate in the construction of active molecular framework, to help form new drugs with good curative effect; in the field of pesticides, can contribute to the creation of high-efficiency and low-toxicity agrochemical products. Therefore, its market potential cannot be underestimated. With the advancement of science and technology, the requirements for its quality and yield will also rise.
    As for 4-bromide, the introduction of bromine gives compounds a different chemical activity. In materials science, it may be used to prepare materials with special electrical and optical properties. For example, in the development of new display materials, bromine-containing compounds may improve the stability and luminous efficiency of materials. In the field of electronic chemicals, 4-bromide may also be an important raw material for the preparation of high-end electronic components. With the vigorous development of the electronics industry, the demand for related fine chemicals in 5G, semiconductor and other industries is surging, and the market prospect of 4-bromide is also full of opportunities.
    Methyl ether, on the other hand, is relatively stable in nature and is often used as a protective group in organic synthesis to facilitate the precise synthesis of complex compounds. In the coatings and adhesives industries, methyl ether compounds may optimize product performance, such as improving the water resistance of coatings and the stickiness of adhesives. Furthermore, with the deepening of the concept of green chemistry, the development and application of environmentally friendly methyl ether products will also become a new growth point in the market.
    In summary, these three have their own capabilities in different fields. With the continuous expansion and upgrading of related industries, their market prospects are quite broad, and they are expected to occupy an important position in the chemical market.