3 Pyridinecarboxylic Acid 4 6 Dichloro
pyridine pyrrole pyrazine piperidine piperazine

3-Pyridinecarboxylic acid, 4,6-dichloro-

    Specifications

    HS Code

    276537

    Name 4,6 - Dichloro - 3 - pyridinecarboxylic acid
    Molecular Formula C6H3Cl2NO2
    Molecular Weight 192.00
    Appearance Solid (usually a white to off - white powder)
    Melting Point Data may vary, typically in a certain range (e.g., 180 - 185°C approximately)
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka There is an acidic pKa value related to the carboxylic acid group (e.g., around 3 - 4)
    Chemical Stability Stable under normal conditions, but may react with strong bases, acids, and reducing/oxidizing agents
    Irritancy May cause skin, eye, and respiratory tract irritation

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    General Information
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    Frequently Asked Questions

    As a leading 3-Pyridinecarboxylic acid, 4,6-dichloro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the use of 3-pyridinecarboxylic acid, 4,6-dichloro-?
    3-Amino, 4,6-dihydroxyl substances have a wide range of uses. In the field of medicine, it is a key component of many drugs. Due to the chemical properties of amino and hydroxyl groups, they can interact with biological macromolecules in the body, such as binding to specific receptors or participating in enzymatic reactions, in order to exhibit therapeutic effects. For example, some antibacterial drugs contain this structure, which can inhibit bacterial growth and reproduction and protect human health by interfering with bacterial cell wall synthesis, nucleic acid metabolism and other mechanisms.
    In the field of materials science, this substance also has important uses. With its unique chemical structure, it can act as a monomer for synthesizing special functional materials. After polymerization, polymer materials with specific properties can be generated, such as materials with good adsorption, ion exchange or optical properties, which are useful in adsorption separation, catalysis and optoelectronic devices.
    In agriculture, 3-amino, 4,6-dihydroxy compounds may be used as precursor structures for pesticide creation. After rational modification and modification, new pesticides with high efficiency, low toxicity and environmentally friendly characteristics have been developed for pest control and crop yield and quality.
    In addition, in the field of organic synthesis, it is often used as an important intermediate. With the activity of amino and hydroxyl groups, other functional groups can be introduced through a series of chemical reactions to build more complex organic molecular structures, providing a key foundation for the synthesis of new organic compounds and promoting the development of organic chemistry.
    What are the physical properties of 3-pyridinecarboxylic acid, 4,6-dichloro-
    The physical properties of 3-hydroxybutyric acid, 4,6-diamino are as follows:
    3-hydroxybutyric acid, which is a colorless to pale yellow liquid with a slight odor. Its melting point is about -43 ° C, and its boiling point is about 207 ° C. It can be miscible with water in any ratio, and it also has good solubility in organic solvents such as ethanol and ether. Because its molecules contain both hydroxyl and carboxyl groups, it has a certain hydrophilicity. In terms of density, it is about 1.13g/cm ³, which is slightly heavier than water. It has the typical partial properties of carboxylic acids and alcohols. Hydroxyl groups can undergo esterification, oxidation and other reactions, and carboxyl groups can participate in many reactions such as salt formation and esterification.
    4,6-diamino compound, mostly white crystalline powder under normal conditions, no obvious odor. The melting point is relatively high, generally in the range of 180-190 ° C. In terms of solubility, it is slightly soluble in cold water, the solubility in hot water is increased, and it is easily soluble in polar organic solvents such as dimethyl sulfoxide, N, N-dimethylformamide, etc. Due to the presence of two amino groups in the molecule, it has a certain alkalinity and can react with acids to form salts. In terms of density, it is about 1.3-1.4g/cm ³. Due to the presence of amino groups in its structure, it is easy to undergo nucleophilic substitution reactions with compounds with active hydrogen, and is often used as an important intermediate in the field of organic synthesis to construct more complex nitrogen-containing compound structures.
    What are the chemical properties of 3-pyridinecarboxylic acid, 4,6-dichloro-
    The chemical properties of 3-hydroxybutyric acid and 4,6-diamino are quite unique.
    Let's talk about 3-hydroxybutyric acid first. This substance is acidic because the carbon atom connected to the hydroxyl group is affected by the adjacent carbonyl group, which makes the hydroxyl hydrogen more easily dissociated and shows a certain acidity. At the same time, it can participate in the esterification reaction, and the hydroxyl group can be dehydrated with the organic acid under the action of the catalyst to form an ester. This reaction is commonly used in the field of fragrance and drug synthesis. In addition, because it contains hydroxyl groups and carbonyl groups, it can undergo oxidation reactions. The hydroxyl group can be oxidized to an aldehyde group or even a carboxyl group, and the carbonyl group can be reduced to an alcohol hydroxyl group
    And 4,6-diamino, the amino group is basic and can react with acids to form salts, such as reacting with hydrochloric acid to form corresponding ammonium salts. It can also participate in nucleophilic substitution reactions. The nitrogen atom in the amino group is rich in lone pair electrons, which can be used as a nucleophilic reagent to attack compounds containing active halogen atoms. Moreover, the existence of two amino groups enables the formation of hydrogen bonds between molecules, which affects the physical properties such as melting point and boiling point of substances. Due to hydrogen bonding, its melting boiling point is relatively high. In organic synthesis, 4,6-diamino groups can be used to construct complex structures such as nitrogen-containing heterocycles, providing an important way for the synthesis of various organic compounds. < Br >
    The two have diverse chemical properties and have important uses and application prospects in many fields such as chemical industry and medicine.
    What is the preparation method of 3-pyridinecarboxylic acid, 4,6-dichloro-
    To prepare 3-pentanoic acid, 4,6-dihydroxy group, the method is as follows:
    First, take a suitable raw material, use glutaric acid anhydride as the base, and obtain it through a multi-step delicate transformation. First, the glutaric acid anhydride is reacted with an appropriate amount of reagents to introduce specific groups into its structure. Glutaric acid anhydride can be esterified with compounds with active hydrogen, such as alcohols, under suitable catalyst and reaction conditions. This step requires attention to the reaction temperature, time and catalyst dosage, so that the reaction is moderate to obtain the intermediate product glutaric acid monoester.
    times, the glutaric acid monoester is specially modified. Hydroxyl groups can be introduced by nucleophilic substitution reaction. With a reagent containing hydroxyl groups, under the catalysis of bases, it reacts with glutaric acid monoester, and carefully adjusts the reaction conditions, so that the hydroxyl groups are precisely substituted at the 4,6 positions to obtain 4,6-dihydroxyglutaric acid monoester. The strength of the base and the ratio of the reagents are all key, which are related to the selectivity and yield of the reaction.
    Then, 4,6-dihydroxyglutaric acid monoester is converted into 3-pentanoic acid. It can be achieved through a elimination reaction. Appropriate elimination reagents, such as strong acids or bases, are selected. Under heating conditions, specific parts of the monoester are eliminated, small molecules are removed, and carbon-carbon double bonds are formed. The final product of 3-pentenoic acid and 4,6-dihydroxyl groups is obtained. In this step, the elimination reaction should pay special attention to the reaction temperature and reagent concentration to prevent the generation of side reactions, so as to ensure the purity and yield of the product. After each step of the reaction, delicate separation and purification methods, such as distillation, recrystallization, column chromatography, etc., are required to remove impurities and make the product pure before it can be used in the next step. After this series of steps, the product of 3-pentenoic acid and 4,6-dihydroxyl can be obtained.
    3-Pyridinecarboxylic acid, 4,6-dichloro - what is the price in the market?
    I look at your question, but I am inquiring about the market price of 3-amino, 4,6-dihydroxyl. However, the price of the two in the market often varies with the quality, the quantity, the change of time, and the supply and demand of the market. It is difficult to explain.
    3-amino is widely used in the field of chemical industry, involving medicine, dyes, and pesticides. If its price is of high quality and huge quantity, or when blocking trade, due to cost dilution, the unit price may drop slightly; if the quality is small, and there are many people seeking it, the price may rise. And the difficulty of its production and the abundance of its sources are also related to the price.
    4,6-Dihydroxyl is also the same. It has its uses in pharmaceutical research and development, preparation of fine chemicals, etc. The origin is different, and the method of picking and preparing is different, resulting in variable costs and prices. If the new production method is introduced, the cost will drop, and the price may decrease; if the production is blocked due to natural disasters, coups, etc., and there are still many people in demand, the price will rise.
    Therefore, if you want to know the exact price of these two, you should go to the chemical raw material market in person, visit various merchants, and inquire about their current quotations; or on the chemical trading network platform, you can get a more accurate number by looking at the recent transaction price.