3-Pyridinecarboxylic acid, 2-chloro-5-nitro-

2 + - 5 + -Amino-3 + -is acidic if it converts to its carboxyl group. The amino group is acidic, while the carboxyl group is acidic. The acidic group of the carboxyl group in this compound is acidic, so it is acidic.
In aqueous solution, the carboxyl group can be solved out of the carboxyl group (H), causing the solution to be acidic. This solution is: R - COOH - R - COO - + H, where R represents the 2 - 5 - amino - 3 - group.
And due to the presence of amino groups, the acid can be reversed. However, as a whole, the acidity of the carboxyl group is even more important. Its acidity is weak, and the carboxyl group is connected to the carboxyl group. In this compound, the presence of 2-and 5-amino groups has a certain impact on the acidity of the carboxyl group.
The acidity of this compound also makes it possible to neutralize and reverse, forming a phase and water. For example, the oxidizer (NaOH) of the carboxyl group is reversed, and the oxidizer (OH) of the carboxyl group is combined with water, while the carboxyl group is formed.
Therefore, 2-5-amino-3-to-its carboxyl group is mainly acidic, and can be reacted to typical acidic substances such as biodegradation and neutralization.

Mercury, cyano, nitrobenzaldehyde, etc. are all highly toxic or highly dangerous chemicals. Mercury, which is liquid at room temperature, is volatile, and mercury vapor inhalation will seriously damage the nervous system and kidneys; cyanide compounds such as potassium cyanide and sodium cyanide are extremely toxic. After entering the human body, they will quickly combine with cytochrome oxidase, block the respiratory chain of cells, cause acute poisoning, and can be fatal in a short time; 3-nitrobenzaldehyde Although not as toxic as the above two, it has irritating effects on the eyes, respiratory tract and skin, and is flammable. It may cause danger in case of open flames and hot topics.
The main uses of these substances are as follows:
Mercury: In ancient times, mercury was often used in alchemy. The alchemists believed that it had a magical effect and could be used to refine elixirs of immortality. Although it was absurd, it reflected the understanding and application of mercury at that time. In traditional medicine, mercury compounds were tried to treat certain diseases, such as skin diseases such as scabies, but due to their strong toxicity, they are rarely used today. In the industrial field, mercury was widely used in the manufacture of thermometers and sphygmomanometers. Due to the stable thermal expansion coefficient of mercury, it can accurately measure temperature and pressure. However, due to its toxicity, many products have gradually abandoned mercury.
Cyanyl: Cyanyl compounds are widely used in the metallurgical industry, especially in the extraction of precious metals such as gold. Gold extraction by cyanidation is a common process. Cyanide can form a stable complex with gold to achieve the separation and extraction of gold from ores. In the field of organic synthetic chemistry, cyanyl can be used as an important functional group to introduce organic molecules into the synthesis of various pharmaceutical, pesticide and dye intermediates, such as some anti-cancer drugs, high-efficiency insecticides and bright dyes. The introduction of cyanyl group is crucial in the preparation process.
3-Nitrobenzaldehyde: It is of great significance in the field of pharmaceutical synthesis and is a key intermediate for the synthesis of various drugs, such as some drugs used to treat cardiovascular diseases and nervous system diseases. In the fragrance industry, 3-nitrobenzaldehyde can impart a unique aroma to fragrances, and is often used to prepare flavors of special fragrances to add aroma levels to products.

To prepare 2-cyanogen-5-amino-3-pyridine carboxylic acid, the following ancient method can be used.
First take the appropriate pyridine derivative as the starting material. With pyridine as the group, the desired group is introduced at a specific position. To obtain 5-amino groups, suitable substituents can be introduced first, and then properly converted to amino groups. For example, nitro groups can be introduced first, and then reduced to amino groups by a reduction method, such as iron powder and hydrochloric acid under co-heating conditions.
As for the introduction of 2-cyano groups, halogenated pyridine can be used to react with cyanide reagents. Usually, halogenated pyridine and cuprous cyanide are heated and refluxed in a suitable organic solvent to undergo nucleophilic substitution reaction, and the halogen atom is replaced by cyanyl group, thereby introducing 2-cyano group.
And the 3-pyridine carboxylic acid part can be obtained by oxidizing a specific position on the pyridine ring. For example, with a suitable oxidant, such as potassium permanganate, under basic conditions, a specific side chain on the pyridine ring can be oxidized and converted into carboxyl groups.
When operating, pay attention to the conditions of each step of the reaction. Temperature, reaction time, and the dosage ratio of reagents are all key. After each step of the reaction, suitable separation and purification methods should be used, such as extraction, recrystallization, column chromatography, etc., to obtain pure products, which can be used in the next step of the reaction. In this way, each step of the reaction is carried out in sequence, and after multiple steps of conversion, 2-cyano-5-amino-3-pyridinecarboxylic acid can be finally prepared.

Nowadays, there are halogen, carboxyl, and amino groups in the market. What is the price? Prices in the market often vary depending on the quality, the wide range of sources, and the amount of demand.
Halogen has a wide range of uses and is indispensable in the chemical industry and pharmacies. However, there are many kinds, chlorine, bromine, iodine, etc. have their own properties and prices are also different. Chlorine is common, because it is easier to produce, the supply is quite abundant, and the price is slightly cheaper, about a few yuan to a few dozen yuan per catty; bromine and iodine, because it is difficult to collect and purify, have high prices. Bromine is around 100 yuan per catty, and iodine is more expensive, or up to hundreds of yuan per catty.
Carboxyl compounds are commonly found in organic synthesis, and most carboxylic acid compounds contain them. Simple carboxylic acids, such as formic acid and acetic acid, are easier to produce and widely sought, with a price of about tens of yuan per catty. However, carboxyl compounds with special structures or high purity can cost hundreds of yuan per catty or even higher due to the complicated preparation process.
Amino compounds are essential in the fields of biochemistry and medicine. Common amino acids are components of proteins, and their prices vary due to different uses and sources. Ordinary edible-grade amino acids cost tens of yuan per catty; while pharmaceutical-grade and high-purity amino acids, due to strict quality control and fine preparation, can cost hundreds of yuan per catty, and rare ones are even more.
To sum up, halogen, carboxyl, and amino groups are in the market, and the price range is wide, ranging from a few yuan per catty to hundreds of yuan per catty, or even more, due to a variety of factors.

In "Tiangong Kaiwu", saltpeter, sulfur, and charcoal are the main components of gunpowder, but the manufacturers related to the mentioned "2-oxygen-5-amino-3-pyridine carboxylic acid" are not listed in the book. Gai "Tiangong Kaiwu" was written in the Ming Dynasty, when chemical knowledge was very different from modern chemical systems. It mainly describes traditional handicrafts, agriculture, industrial production and many other techniques, and it is difficult to involve the specific products of modern fine chemistry.
In the field of modern chemistry, there are many manufacturers of "2-oxygen-5-amino-3-pyridine carboxylic acid", which are distributed all over the world. In China, many fine chemical enterprises focus on the research and development and production of such compounds. Such enterprises are mostly concentrated in places with developed chemical industries, such as the Yangtze River Delta, the Pearl River Delta and the Bohai Rim region. The reason is that these regions have a complete chemical industry chain, convenient access to raw materials, and strong scientific research strength, which is conducive to Product Research & Development and production.
However, if you want to know the specific manufacturer in detail, you really need to use modern business information channels, such as chemical product databases, industry exhibition materials, professional chemical consulting agency reports, etc. These channels can provide the latest and accurate manufacturer directory, production capacity, product specifications and other information to meet the needs of modern industrial production and scientific research, which cannot be covered by ancient books such as Tiangong Kaiwu.