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What are the chemical properties of 2-chloro-5-methyl-3-pyridinecarboxylic acid
Fu2 + - 5-methyl-3-pentenoic acid is characterized by its chemical properties. In this compound, the polyatom of dimethylbenzene is highly reactive, and it often plays an important role in the reaction of oxidants. In the reaction of dimethylbenzene, dimethylbenzene atoms can be reactive due to the reaction of antibodies, such as addition and substitution.
Because of the reaction of 5-methyl-3-pentenoic acid, its ethylenes are also reactive centers. Ethylenes are rich in children and are vulnerable to the attack of dimethylbenzene. For example, the addition of, according to's, atoms added to the carbon atom containing more, atoms added to those containing less, this inverse can increase the functionality of the compound, show its use.
In addition, the carboxyl group is another important function of 5-methyl-3-pentenoic acid. The carboxyl group is acidic and can be neutralized and reversed to form a phase of carboxylic acid. And the carboxyl group can be esterified and reversed. Under the catalysis of acid, the alcohol is reversed to form an ester compound. This reaction is often used in the synthesis of, which can be used for fragrance, solution and other compounds.
In addition, the methyl phase in the molecule is fixed, but under specific conditions, such as oxidation, methyl can be oxidized, and the chemical properties of the whole molecule can be improved. In addition, 2 + - 5 -methyl-3 -pentenoic acid exhibits rich chemical properties due to the partial interaction of methyl, alkene, carboxyl and methyl, etc., which is important for research in fields such as synthesis and chemical engineering.
What are the main uses of 2-chloro-5-methyl-3-pyridinecarboxylic acid?
2 + -Deuterium-5-methyl-3-pentenoic acid, this substance has important uses in many fields.
In the field of pharmaceutical chemistry, it can be used as a key intermediate. With its unique chemical structure, it can be cleverly combined with other compounds through specific chemical reactions to synthesize drugs with special curative effects. For example, in the development of drugs for the treatment of cardiovascular diseases, it may participate in the construction of active molecular structures, which play a positive role in regulating blood lipids, improving vascular elasticity, and helping to overcome related diseases.
In the field of materials science, it may become a raw material for the preparation of special polymer materials. With the help of polymerization, it can be polymerized with other monomers to form polymers with excellent performance. This polymer may have good thermal stability and mechanical properties, and can be used to make lightweight and high-strength materials required in the aerospace field, contributing to the development of the aviation industry; or it may emerge in the field of electronic materials, used to make high-performance electronic components packaging materials.
In the field of organic synthesis, it serves as a key building block for the synthesis of complex organic compounds. Organic chemists can build organic molecules with diverse structures and functions through selective functional group conversion, carbon-carbon bond formation, and other reactions according to their structural characteristics. For example, the synthesis of biologically active natural product analogs lays the foundation for the development of new drugs and biological activity research.
In addition, in the fragrance industry, due to its unique chemical structure, or appropriately modified into compounds with special aromas, it provides raw materials for the formulation of novel and unique fragrances, bringing people a different olfactory experience. In short, 2 + -deuterium-5-methyl-3-pentenoic acid has great application potential in many fields, and is of great significance for promoting technological development and innovation in various fields.
What are the synthesis methods of 2-chloro-5-methyl-3-pyridinecarboxylic acid
To prepare 2-pentyne-5-methyl-3-hexenoic acid, the following ancient methods can be used.
First, start with the corresponding halogenated hydrocarbon. First, take a suitable halogenated alkene and make it nucleophilic substitution reaction with sodium alkyne. The preparation of sodium alkyne can be obtained by reacting alkyne with sodium metal in a suitable solvent such as liquid ammonia. When the halogenated alkyne meets the sodium alkyne, the halogen atom leaves, and the alkynyl group is substituted to obtain an intermediate containing the alkynyl group and the alkenyl group. Subsequently, this intermediate is reacted with carbon dioxide under suitable conditions, and after acidification treatment, carboxyl groups can be introduced to obtain the target product 2-pentyne-5-methyl-3-hexenoic acid. This process requires attention to the precise control of the reaction conditions, such as temperature and solvent selection, to ensure that the reaction proceeds in the desired direction.
Second, starting from the enol compound. The enol can be protected by a suitable protective group to prevent it from reacting without end in the subsequent reaction. Afterwards, the enol derivative and the alkyne derivative are coupled under the action of a specific catalyst. This catalyst may be a transition metal complex or the like. After the reaction is completed, the protecting group is removed, and then the enol is converted into carboxylic acid through an oxidation step, which can also achieve the purpose of preparing 2-pentyne-5-methyl-3-hexenoic acid. In this path, the selection and removal of the protecting group, as well as the consideration of oxidation conditions, are very important, which are related to the purity and yield of the product.
Third, consider aldosteroids as starting materials. Aldosteroids can first undergo nucleophilic addition reaction with alkynides to obtain alcohols containing alkynyl groups. Subsequently, the alcohols are dehydrated to form alkynes. 2-Pentyne-5-methyl-3-hexenoic acid is obtained by oxidizing the alcohol hydroxyl group to carboxylic group with suitable oxidant. In this route, the selectivity of nucleophilic addition, the conditions of dehydration reaction and the control of oxidation reaction are all key factors for successful preparation, which need to be carefully considered and handled with caution.
What is the price range of 2-chloro-5-methyl-3-pyridinecarboxylic acid on the market?
Today there is 2-hydroxy-5-methyl-3-nitrobenzoic acid, and you want to know its price range in the market. This compound may have specific uses in the chemical industry, but its price often varies depending on factors such as quality, supply and demand, origin, and purchase volume.
If the quality is high, the purity is very high, and the purchase volume is small in the peak demand season, the price may be high. On the contrary, if the quality is ordinary, the market supply is sufficient, and the purchase volume is large, the price may be relatively easy.
According to past market conditions and general market speculation, in the general chemical raw material trading market, small batch purchases, with a purity of about 95%, the price per gram may range from tens of yuan to hundreds of yuan; if it is industrial grade, the purity is slightly lower, and a large number of purchases, the price per kilogram may be around thousands of yuan. But this is only a rough estimate, and the actual price should be subject to the current quotations of various suppliers. To get an accurate price, you can consult chemical product suppliers and online chemical trading platforms for detailed comparison before you can know the exact price.
What are the manufacturers of 2-chloro-5-methyl-3-pyridine carboxylic acid?
There are many manufacturers of 6-deuterium-5-methyl-3-pentenoic acid in the world.
As far as I know, Sigma-Aldrich is a giant in chemical reagents, famous for its wide range of products, high quality, and trusted in chemical, biological and other fields. Therefore, Sigma-Aldrich may supply 6-deuterium-5-methyl-3-pentenoic acid.
There is also Buckingway Technology Co., Ltd., which is also a leader in the industry. It focuses on providing high-quality chemicals and related services for scientific researchers and enterprises, and is committed to meeting the diverse needs of customers. 6-Deuterium-5-methyl-3-pentenoic acid and other products, or involved in its business.
In addition, TCI (Tokyo Chemical Industry Co., Ltd.) has made great achievements in the field of organic synthesis reagents. With its rich product line and exquisite technology, it provides customers around the world with a variety of high-quality chemicals. 6-Deuterium-5-methyl-3-pentenoic acid, it is expected that TCI also operates.
However, the market is unpredictable, and the operating conditions and product supply of manufacturers may change from time to time. If you want accurate information about this product, you need to go to the official website of each manufacturer for detailed investigation, or consult the relevant sales and customer service personnel in detail before you can get the exact information.