3 Pyridinecarboxylic Acid 2 Chloro 5 Hydroxy
pyridine pyrrole pyrazine piperidine piperazine

3-pyridinecarboxylic acid, 2-chloro-5-hydroxy-

    Specifications

    HS Code

    192229

    Name 2-chloro-5-hydroxypyridine-3-carboxylic acid
    Chemical Formula C6H4ClNO3
    Molar Mass 173.554 g/mol
    Appearance Solid (predicted)

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    Frequently Asked Questions

    As a leading 3-pyridinecarboxylic acid, 2-chloro-5-hydroxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-chloro-5-hydroxy-3-pyridine carboxylic acids?
    Fu6-bromo-5-methoxy-3-indoleacetic acid is a genus of organic compounds. It has unique physical properties and is very important in chemical research and related fields.
    Looking at its properties, it often appears solid at room temperature. The color may be white to light yellow, and its shape may be powdery. The texture is fine. This shape is convenient for weighing, storage and subsequent experimental operations.
    The melting point is about a specific temperature range. This property is a key indicator when identifying and purifying the substance. By accurately measuring the melting point, the purity can be determined. If the melting point of the sample is consistent with the literature and the melting range is very narrow, the purity is quite high; conversely, if the melting point deviation is large and the melting range is wide, it contains more impurities.
    Solubility is also an important property. In common organic solvents, such as ethanol and dichloromethane, it can show a certain solubility. Ethanol has a moderate polarity and can interact with 6-bromo-5-methoxy-3-indoleacetic acid molecules to form hydrogen bonds, so that it dissolves in it; although dichloromethane has a weak polarity, it can also dissolve to a certain extent because of its specific molecular structure. In water, the solubility is relatively limited, and the hydrophobic groups account for a large proportion of its molecular structure, and the interaction with water molecules is weak, so it is difficult to dissolve.
    In addition, the density of the substance also has characteristics. Although the specific value varies slightly due to the measurement conditions, there is a fixed density value under specific conditions. This is a necessary consideration when it comes to operations such as quantitative mixing and phase separation of substances. In a specific solvent, due to the different densities of the solvent, it may be stratified or uniformly dispersed, which affects the reaction process and product separation.
    In summary, the physical properties of 6-bromo-5-methoxy-3-indoleacetic acid, such as properties, melting point, solubility, density, etc., are interrelated and significant in chemical research, synthesis and application. Researchers need to be familiar with and make good use of them to achieve the expected experimental purposes.
    What are the chemical properties of 2-chloro-5-hydroxy-3-pyridine carboxylic acids
    2 + -Deuterium-5 + -hydroxyl-3 + -carboxylic acids are a class of organic compounds with the following chemical properties:
    First, acidic. Such compounds contain carboxyl groups (-COOH), which can partially ionize hydrogen ions (H 🥰) in water, making them acidic. It can neutralize with bases, and take the reaction with sodium hydroxide (NaOH) as an example to generate corresponding carboxylic salts and water. The reaction formula is: R - COOH + NaOH → R - COONa + H 2O O, where R represents 2 + - deuterium - 5 + - hydroxyl - 3 + - to its carboxylic acid except for the carboxyl group.
    Second, esterification reaction. Under the catalysis of concentrated sulfuric acid and heating conditions, 2 + - deuterium - 5 + - hydroxyl - 3 + - to its carboxylic acid can be esterified with alcohol to form esters and water. For example, when reacting with ethanol (C 2O H OH), the reaction formula is: R - COOH + C 2O H OH (concentrated sulfuric acid, Delta) R - COOC 2O H + H 2O O, the resulting esters often have a special fragrance and are widely used in food, flavors and other fields.
    Third, the substitution reaction. The hydroxyl group in the carboxyl group can be replaced by other atoms or atomic groups. If reacting with phosphorus halides (such as PCl, PCl, etc.), the hydroxyl group can be replaced by chlorine atoms to form an acid chloride. Take the reaction with PCl as an example, the reaction formula is: R-COOH + PCl → R-COCl + POCl 🥰 + HCl. Acyl chloride has high activity and is an important intermediate in organic synthesis.
    Fourth, decarboxylation reaction. Under specific conditions, 2 + -deuterium-5 + -hydroxy- 3 + -to its carboxylic acid can undergo a decarboxylation reaction, that is, the decarboxylation of carbon dioxide (CO ²) from the carboxyl group. For example, under heating or certain catalysts, such reactions may occur to generate organic compounds with one less carbon atom. This property can be used for carbon chain shortening in organic synthesis.
    What is the main use of 2-chloro-5-hydroxy-3-pyridine carboxylic acid?
    2 + -Deuterium-5 + -hydroxy- 3 + -to its peptone acid, its use is very wide.
    The first is the field of medicine. In the field of pharmacy, this compound is often a key raw material. It has a unique structure and can participate in a variety of chemical reactions to make special drugs. Or it can adjust the physiological function of the human body and treat various diseases. For example, in some diseases of the nervous system, it can relieve nervous tension through specific pharmacological effects, promote the normal transmission of neurotransmitters, and reduce the symptoms of patients.
    This is the way of material science. It can be used as an additive for special materials to change the properties of materials. If added to polymer materials, it can increase its stability and mechanical properties. In aerospace materials, it can help materials resist extreme environments, such as high temperature, high pressure, etc., to ensure the safe operation of aircraft.
    Furthermore, in the path of scientific research and exploration. It is an important chemical reagent for researchers to explore the mechanism of chemical reactions. By studying the reactions it participates in, the essence of many chemical processes can be understood, providing a basis for the construction and improvement of new chemical theories. Help chemistry to move forward and open up new cognitive fields.
    And it can also be used in the field of agriculture. Or make special fertilizer additives to help plants absorb nutrients, enhance plant disease resistance, improve crop yield and quality, and contribute to the sustainable development of agriculture. Therefore, 2 + -deuterium-5 + -hydroxy- 3 + -peptone acid plays an indispensable role in various fields and plays an important role in promoting the progress of various industries.
    What is the preparation method of 2-chloro-5-hydroxy-3-pyridinecarboxylic acid?
    To prepare 2-hydroxy-5-amino-3-nitrobenzoic acid, the following method can be used.
    Take suitable raw materials first, such as benzoic acid derivatives as the starting material. Because the carboxyl group is the meta-localization group, the amino group and the hydroxyl group are the ortho-and para-localization groups, and the nitro group is the meta-localization group, the reaction sequence needs to be cleverly planned.
    Nitrification reaction can be carried out on benzoic acid first, and the mixed acid of concentrated sulfuric acid and concentrated nitric acid is used as the nitrification reagent. Under heating conditions, nitro groups can be introduced into the benzene ring of benzoic acid to obtain m-nitrobenzoic acid. This step uses the localization effect of nitro groups to lay the foundation for subsequent reactions.
    Then, p-nitrobenzoic acid Using iron and hydrochloric acid as reducing agents, nitro groups can be reduced to amino groups to obtain m-aminobenzoic acid. However, it should be noted that the reaction conditions of this process need to be precisely controlled to prevent the overreaction of amino groups.
    Then go through the hydroxylation step. It can be achieved by a series of reactions such as halogenation and hydrolysis. First, a suitable halogenation reagent, such as liquid bromine and iron powder, is used to catalyze the halogenation of the benzene ring of m-aminobenzoic acid, and halogen atoms are introduced at suitable positions. After heating and hydrolysis with sodium hydroxide aqueous solution, the halogen atoms are replaced by hydroxyl groups, and finally 2-hydroxy-5-amino-3-nitrobenzoic acid is obtained.
    During the entire preparation process, the reaction conditions at each step need to be carefully controlled, such as temperature, reaction time, reagent dosage, etc., and attention should be paid to the purification and separation of intermediates to improve the purity and yield of the target product.
    What is the price range of 2-chloro-5-hydroxy-3-pyridinecarboxylic acid in the market?
    Alas! If you ask about the price range of cyanogen-5-amino-3-carboxylic salts in the market, this is not an easy thing to say. The market price often fluctuates due to changes in time, place, and supply and demand.
    I have heard that cyanide compounds are many toxic, and their trading controls are strict, which is comparable to unusual transactions. And 5-amino-3-carboxylic salts, or due to the difficulty of preparation and the different uses, their prices are also different from normal products.
    In the past, the prices of these chemicals fluctuated from time to time due to the abundance of raw materials and the clumsy process. If the raw materials are easily available and the process is advanced, the price may be slightly lower; on the contrary, if the raw materials are scarce and the preparation is difficult, the price will be high.
    If you want to know the range of the current market price, you should carefully check the records of chemical transactions, interview experts in the industry, or consult relevant market survey agencies. Only then can you get a more accurate number to show the suitability of the price. Unfortunately, I can't get the exact value in time. I can only state this roughly. I hope the inquirer will forgive me, and you can follow this path to find the actual price.