3-Pyridinecarboxylic acid, 2,4-dibromo-

3-Pyridinecarboxylic acid, 2,4-dibromo - This substance is an organic compound. In terms of physical properties, it may be a solid under normal conditions. Due to the presence of bromine atoms, the intermolecular force is enhanced, and the melting boiling point may be higher. And because the molecular structure contains polar groups, it may have a certain solubility in polar solvents.
Chemically, the pyridine ring is aromatic and can undergo electrophilic substitution reactions. And because the bromine atom is an ortho-para-site group, the substitution reaction mostly occurs at the 3rd and 5th positions of the pyridine ring. The carboxyl group is acidic and can neutralize with the base to form the corresponding carboxylate. In addition, the bromine atom is highly active and can be replaced by other functional groups under appropriate conditions. Because pyridine cyclic nitrogen atom has lone pair electrons, it can be used as a ligand to form complexes with metal ions, showing unique chemical behaviors. This compound may have important uses in the field of organic synthesis, and can be used as an intermediate to participate in the preparation of a variety of complex organic compounds.

3-Pyridinecarboxylic acid, 2,4-dibromo - This substance is quite widely used. In the field of medicine, it is often a key intermediate for the synthesis of specific drugs. Due to its unique chemical structure, it can participate in the construction of many drug molecules, helping to develop new drugs with specific curative effects, such as some drugs with antibacterial and anti-inflammatory properties. During the synthesis process, this compound may play a key role. Through specific chemical reactions, it is combined with other chemical substances to shape the active structure of the drug to achieve the expected pharmacological effect.
In the field of materials science, it has also emerged. It can be processed by specific processes to prepare materials with unique functions. For example, some materials with recognition or adsorption properties for specific substances may need to be prepared with this compound as a starting material. After a series of reactions, the material is endowed with special chemical properties, which makes it practical in environmental monitoring, substance separation, etc.
Furthermore, in the field of organic synthetic chemistry, it is an extremely important synthetic building block. Organic chemists can use various organic reactions to expand and modify molecular structures based on their structural characteristics to synthesize complex and functional organic compounds, providing diverse possibilities for the development of organic chemistry and promoting the creation and research of new organic compounds.

To prepare 2,4-dibromo-3-pyridinecarboxylic acid, the following method can be used.
First, pyridine is taken as the starting material. The nitrogen atom of pyridine is basic, and the electron cloud density of the pyridine ring can be reduced, making the electrophilic substitution reaction more difficult than benzene, and mainly occurs at the β position (3 position).
For the bromination reaction of pyridine, liquid bromine can be used to react in the presence of an appropriate catalyst such as iron powder or iron tribromide. Due to the relatively high electron cloud density at the 3 position on the pyridine ring, bromine atoms preferentially replace hydrogen atoms at the 3 position to generate 3-bromopyridine. However, this step requires attention to control the reaction conditions, and the temperature should not be too high to avoid excessive bromination.
After 3-bromopyridine is obtained, another bromination reaction is carried out. At this time, due to the fact that the bromine atom is an ortho-para-site group and the electron cloud density of the pyridine ring is low, when brominated again, the 2nd and 4th positions are relatively susceptible to substitution reactions due to the influence of the bromine group. By controlling the amount of bromine and the reaction conditions, the bromine atom is substituted at the 2nd and 4th positions to generate 2,4-dibromopyridine.
Then, the carboxylation reaction of 2,4-dibromopyridine is carried out. The Grignard reagent method can be used to react 2,4-dibromopyridine with magnesium in anhydrous ether and other solvents to form Grignard reagent, and then carbon dioxide gas is introduced. After acidic hydrolysis, one of the bromine atoms on the pyridine ring can be replaced with a carboxyl group, and finally 2,4-dibromopyridine-3-picolinecarboxylic acid is obtained. The whole process requires precise control of the reaction conditions at each step, such as temperature, reagent dosage, reaction time, etc., to improve the yield and purity of the product.

I don't know the price of "3 - Pyridinecarboxylic acid, 2,4 - dibromo -" in the market. However, if you want to estimate its price, you need to consider various factors.
First, the purity of this product is essential. If the purity is high and there are few impurities, it is suitable for high-end fields such as fine chemicals and pharmaceutical research and development, and the price will be high; if the purity is low, it can only be used for general industrial purposes, and the price will be slightly cheaper.
Second, the market supply and demand is also heavy. If the demand is strong and the supply is scarce, if the demand for this product increases sharply in the development stage of a specific new drug, the price will rise; conversely, if the supply exceeds the demand, the price will drop easily.
Third, the difficulty of preparation is related to cost. If the preparation requires complex processes, expensive raw materials and harsh conditions, the cost is high and the price is also high; if the preparation is easy and the cost is controllable, the price may drop.
Fourth, the manufacturer's brand and market reputation are different. Well-known large factories, strict quality control, excellent product quality, and their price may be higher than that of unknown small factories.
Although I have no conclusive price, according to the above, you can determine your own approximate price range in the market, or consult chemical raw material suppliers and industry experts to get a more accurate price.

3-Pyridinecarboxylic acid, 2,4-dibromo-The essential rules for the storage of this substance are related to the stability of its quality and must be specified. The storage place should be selected in a cool and dry place. If it is in a high temperature or humid place, it may be chemically changed due to heat, or its pure quality will be damaged due to moisture.
This agent should be sealed and stored. If it is exposed to air, its ingredients may combine with various substances in the air, such as oxygen and water vapor, causing it to deteriorate. And it must be kept away from fire and heat sources. Because it may be flammable or chemically active, it may be dangerous to change in case of fire or heat, such as the risk of combustion or explosion.
Also, it is appropriate to store it separately from foreign chemicals such as oxidizing agents and reducing agents. This is due to the chemical properties of 3-pyridinecarboxylic acid, 2,4-dibromo-or violent reactions with them, which endanger the safety of storage and damage its quality. The storage place should be equipped with appropriate emergency treatment equipment for leakage and suitable containment materials. In case of leakage, it can be disposed of quickly to prevent its diffusion from causing greater harm. In this way, the agent should be properly stored to ensure its quality and use.