3-PYRIDINECARBOXAMIDOXIME

The chemical structure of 3-pyridine formamide oxime is quite exquisite. Looking at this compound, the pyridine ring is the core structure. The pyridine ring has a six-membered heterocycle, which is cleverly connected by five carbon atoms and one nitrogen atom. It has a planar structure, giving the molecule specific stability and electronic properties.
At the 3rd position of the pyridine ring, there is a group of formamide oxime. The formamide oxime part, formyl (-C (O) -NH _ 2) is related to the pyridine ring by carbonyl. In the carbonyl group, carbon and oxygen are connected by a double bond, and the electron cloud distribution of this double bond is unique, which affects the polarity and reactivity of the molecule. The nitrogen atom in the amide group has lone pairs of electrons, which can participate in many chemical reactions, such as the formation of hydrogen bonds.
Furthermore, the oxime group (-C (= NOH)) is also connected to the same carbon atom. The nitrogen-oxygen double bond in the oxime group forms a conjugated system with the single bond of carbon and nitrogen, which further affects the electron cloud distribution of the molecule and enriches its chemical properties. This conjugate system can delocalize electrons and enhance the stability of the molecule. Overall, the chemical structure of 3-pyridine formamide oxime is shaped by the interaction of pyridine rings with specific substituents, which together shape its unique chemical properties and potential application characteristics.

The use of 3-pyridine formamide oxime is quite important. In the field of medicine, it is often a key raw material for the creation of new antibacterial drugs. Because of its unique chemical structure, it can affect the key metabolic pathways of bacteria, thereby exhibiting antibacterial effect and helping to fight diseases caused by various bacteria.
In the field of materials science, it also has significant functions. Or it can participate in the preparation of special functional materials, such as materials with excellent adsorption properties. Due to its structural properties, it can interact with specific substances, so that the material exhibits highly selective adsorption of certain ions or molecules, and has potential applications in environmental purification, substance separation, etc.
Furthermore, in the field of organic synthesis, 3-pyriformamide oxime is an important intermediate. With its activity check point, it can take advantage of various organic reactions to construct complex organic molecular structures. Chemists can use this to synthesize many organic compounds with special functions or biological activities, laying the foundation for the development of new drugs, the preparation of fine chemicals, etc., promoting the continuous progress of organic synthesis chemistry, and expanding the boundaries of human beings in the field of molecular creation.

3-Pyriformamide oxime is a unique chemical substance with many specific physical properties. Its appearance is often white to off-white crystalline powder, fine texture, and when viewed in natural light, it shows a soft luster. This form is convenient for its use and processing in various chemical reactions and experimental operations.
When it comes to solubility, 3-pyriformamide oxime exhibits good solubility in common organic solvents such as methanol and ethanol. The interaction between methanol molecules and the substance molecules through hydrogen bonds makes 3-pyriformamide oxime uniformly dispersed in the methanol system to form a clear and transparent solution. In water, its solubility is relatively limited and only slightly soluble. This solubility characteristic is of great significance when separating, purifying and selecting a specific reaction medium.
Its melting point is also one of the important physical properties. After precise determination, the melting point of 3-pyriformamoxime is in a specific temperature range. When heated to the melting point, the substance transitions from a solid state to a liquid state, and this process requires specific heat absorption to overcome the lattice energy. Precise understanding of the melting point can be used to identify the purity of the substance. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point is reduced and the melting range is widened.
In addition, the density of 3-pyriformamoxime also has its characteristics. Under normal temperature and pressure, it has a certain density value, which reflects its mass per unit volume. It is a key consideration for quantitative research involving the substance and the ratio of the reaction system, etc., which affects the reaction process and the quality and yield of the final product.

The preparation method of 3-pyridine formamide oxime, although the ancient books do not contain this detailed name, can be deduced according to the principle of chemical preparation.
First take the pyridine as the base, and introduce the carboxyl group at the 3-position of the pyridine. This can be done through pyridine and suitable reagents, such as acyl halides with carboxylation ability, acid anhydrides, etc., under suitable catalyst and reaction conditions, the 3-position hydrogen of the pyridine is replaced by a carboxyl group to obtain 3-pyridine carboxylic acid.
3-pyridinecarboxylic acid is obtained, and then it is reacted with ammonia or amine compounds. This reaction requires appropriate temperature, pressure and catalyst to promote the condensation of its carboxyl group with ammonia or amine amino group, dehydrate one molecule of water, and obtain 3-pyridineformamide.
So far, 3-pyridineformamide is obtained. To form 3-pyridineformamide oxime, hydroxylamine reagent needs to be reacted with it. Hydroxylamine can undergo nucleophilic addition reaction with the carbonyl group of 3-pyridineformamide, and through the process of intramolecular rearrangement, the final product is 3-pyridineformamide oxime. When reacting, it is necessary to carefully adjust the reaction conditions, such as temperature, pH, reaction time, etc. If the temperature is too high or too low, it can affect the reaction rate and product purity; if the pH is not suitable, or the reaction direction is deviated, the product is impure. And a suitable solvent should be selected to dissolve the reactants and facilitate the reaction. In this way, following this series of steps, 3-pyridine formamide oxime may be obtained.

3-Pyriformamide oxime is a chemical substance. When using it, many things must be paid attention to.
First safety protection. This substance may be dangerous, and protective equipment is essential when exposed. It is necessary to wear suitable protective clothing, such as chemical-resistant clothing, to prevent it from coming into contact with the skin and causing damage to the skin. Protective gloves must also be worn. The material should be able to effectively block the substance and avoid hand contamination. Eye protection is also key. Wearing goggles can prevent damage to the eyes. If it splashes into the eyes, it may lead to serious consequences.
Operating environment should also be cautious. It should be operated in a well-ventilated place, preferably in a fume hood. Good ventilation can disperse volatile substances in time, reduce their concentration in the air, and reduce the risk of inhalation. If used in a confined space, volatile gases can accumulate and be easily inhaled by the human body, harming health.
Furthermore, it is essential to know its chemical properties. Understand its stability, reactivity with other substances, etc. In case of certain chemical substances, or cause violent reactions, causing danger. Before use, read the relevant information carefully and clarify its characteristics to prevent problems before they occur.
Storage should not be sloppy. It should be stored in a cool, dry place, away from fire and heat sources. Improper storage, or cause changes in its properties, causing safety problems. And must be stored separately from other incompatible substances to avoid accidental reactions.
During use, strictly follow the operating procedures. Weighing, mixing and other steps are all operated according to the specifications and cannot be changed without authorization. A little carelessness may cause the experiment to fail, or even endanger personal safety.