3-pyridinecarboxaldehyde, 5-chloro-6-hydroxy-

5-Chloro-6-hydroxy-3-pyridyl formaldehyde, the physical properties of this substance are as follows:
Under normal temperature, it is usually solid, and the specific appearance may vary slightly due to the preparation process and purity. However, it is mostly white to light yellow powder or crystalline. When viewed in sunlight, it has a certain luster.
Its melting point is an important physical constant. After accurate determination, it is about a specific temperature range. This temperature value is of great significance for identification and purity determination. In chemical synthesis and quality control, the determination of the melting point is often used to determine the purity.
In terms of solubility, it has a certain solubility in organic solvents, such as common ethanol and acetone. For ethanol, as a common organic solvent, the hydroxyl group in the molecule can form a hydrogen bond with the hydroxyl group of 5-chloro-6-hydroxyl-3-pyridyl formaldehyde, so it has a good solubility in ethanol; there is an intermolecular force between the carbonyl group of acetone and the aldehyde group of the compound, which also makes it partially soluble in acetone. In water, although the hydroxyl group in the molecule can form a hydrogen bond with water, the presence of chlorine atoms and pyridine rings increases its overall hydrophobicity, so the solubility is relatively limited.
In addition, the density of this substance is also one of its physical properties. Although the exact density value needs to be determined by professional instruments and varies due to temperature, pressure and other conditions, its density is slightly higher than that of common light organic solvents. In the process of chemical experimental operations, such as extraction and separation, this property is of reference value for determining its distribution in different phases. And because of its functional groups such as aldehyde groups, hydroxyl groups and chlorine atoms, under specific conditions, it can cause a variety of physical changes. In case of some reagents, color reactions can occur, etc. This is the embodiment of its unique physical properties.

5-Chloro-6-hydroxy-3-pyridyl-formaldehyde, an organic compound. Its chemical properties are interesting and it shows potential uses in many fields.
In terms of reactivity, aldehyde groups are quite active. Alaldehyde groups are highly reactive functional groups and can participate in many classical organic reactions. For example, they can condensate with compounds containing active hydrogen. React with amines to form Schiff bases. This reaction condition is relatively mild and is often used in organic synthesis to construct nitrogen-containing heterocycles or introduce nitrogen-containing functional groups. Furthermore, aldehyde groups can be oxidized. Common oxidants such as potassium permanganate and potassium dichromate can oxidize them to carboxylic groups to form 5-chloro-6-hydroxy-3-pyridinecarboxylic acid.
Hydroxy groups also have specific reactivity. The oxygen atom of the hydroxyl group is rich in lone pair electrons and is alkaline to a certain extent, which can undergo esterification reaction with acids. If it meets with acid chloride or acid anhydride, under the action of appropriate catalysts, it can form corresponding ester compounds. This property is of great significance in the fields of drug synthesis, material preparation, etc. The structure of the compound can be modified through esterification to change its physical and chemical properties.
In addition, the chlorine atom in this compound is not "safe". Chlorine atoms can participate in nucleophilic substitution reactions. When confronted with suitable nucleophilic reagents, chlorine atoms can be replaced, thereby introducing other functional groups to achieve diverse construction of molecular structures.
The chemical properties of 5-chloro-6-hydroxy-3-pyridyl formaldehyde make it a much-anticipated compound in the fields of organic synthesis, drug development, and materials science, providing rich possibilities for many chemical reactions and applications.

The method of preparing 3-pyridine formaldehyde, 5-chloro-6-hydroxy group, is often formed by a multi-step reaction. The first step is to choose a suitable starting material, such as a compound with a pyridine ring, or a structure containing a pyridine ring that can be converted into a pyridine ring.
One method is to use a raw material containing a pyridine ring with a suitable substituent to perform a halogenation reaction at a specific position under specific conditions. If a suitable halogenating agent is used, at a suitable temperature, in the presence of a solvent and a catalyst, the raw material is introduced into the chlorine atom at a specific check point of the pyridine ring. In this step, attention should be paid to the selectivity of the reaction to ensure that the chlorine atom is accurately added to the expected 5 positions.
Next step, the hydroxylation reaction is performed at another specific position on the pyridine ring. Hydroxyl groups can be introduced at the 6 position with specific reagents under appropriate conditions by nucleophilic substitution or other related reaction pathways. This process requires precise regulation of reaction conditions to avoid unnecessary side reactions.
As for the introduction of aldehyde groups at the 3 position, it is common to use functional group conversion methods. For example, groups that can be converted into aldehyde groups, such as alcohol hydroxyl groups, are introduced first at the 3 position, and then oxidized to aldehyde groups by oxidation reactions. The oxidizing agent used in the oxidation step needs to be carefully selected, depending on the structure of the raw material and the reaction environment, such as mild oxidizing agents to ensure that other groups are not affected. After each step of the reaction, a suitable separation and purification method, such as column chromatography, recrystallization, etc., is required to obtain a pure intermediate or target product to ensure the purity and yield of the final product.

3-Pyridyl formaldehyde, 5-chloro-6-hydroxyl, is useful in many fields such as medicine and chemical industry.
In the field of medicine, it may be a key intermediate for the synthesis of new drugs. The existence of special functional groups such as gaidine, aldehyde, hydroxyl and chlorine atoms endows it with unique chemical and biological activities. Through chemical synthesis, it can be integrated into the molecular structure of drugs to change the physicochemical properties and pharmacological activities of compounds, such as enhancing the affinity of drugs to specific targets and enhancing the therapeutic effect. For example, in the development of anti-tumor drugs, these compounds are used to construct targeted molecules that precisely act on tumor cells and inhibit their growth and spread.
In the field of chemical industry, it has an outstanding position in the field of organic synthesis. It is often used as a starting material or intermediate to participate in the construction of complex organic compounds. With its multi-functional group properties, it can be combined with other organic reagents through different chemical reactions, such as condensation reactions, redox reactions, etc., to prepare organic materials with different functions, such as fluorescent materials. Because of its special structure, it may enable the prepared materials to have unique optical properties, and may have applications in the field of optoelectronics, such as Light Emitting Diodes, sensors, etc. In the coating industry, it may also be added to coatings as a modifier to improve the adhesion and corrosion resistance of coatings.
In summary, 3-pyridyl-formaldehyde, 5-chloro-6-hydroxy compounds have great potential in the fields of medicine and chemical industry. With the deepening of scientific research, their application prospects may be broader.

I look at your question, but I am inquiring about the market price range of 3-pyridyl formaldehyde and 5-chloro-6-hydroxyl. However, the price of this product is difficult to determine, and it is subject to many factors.
First, the price of raw materials fluctuates, which often causes the price of this product to fluctuate. If raw materials are not easy to obtain or are in short supply, the price must rise; if raw materials are abundant, the price may stabilize and decline.
Second, the difficulty and cost of production are also key. If the preparation requires complicated processes, high energy consumption, or strict equipment requirements, the cost is high and the price is not cheap; if the process is simple and the cost is controllable, the price may be close to the people.
Third, the trend of market supply and demand, especially the price. If there are many applicants, but there are few producers, the supply is in short supply, and the price will rise; if the supply exceeds the demand, the merchant will sell the goods, or reduce the price to compete.
Fourth, the difference between regions also makes the price different. In prosperous cities, the demand may be prosperous, the logistics is convenient, and the price may be different; in remote places, the supply and demand and logistics conditions are different, and the price will also change.
With common sense, the price of this compound may range from tens to hundreds of yuan per gram due to its use and production characteristics. However, this is only a rough estimate. To know the exact price, you need to consult chemical raw material suppliers in detail, or check the recent market conditions on the chemical product trading platform in order to obtain an accurate estimate.