3 Pyridinecarbonitrile 5 Hydroxy 9cl
pyridine pyrrole pyrazine piperidine piperazine

3-Pyridinecarbonitrile,5-hydroxy-(9cl)

    Specifications

    HS Code

    572942

    Name 3 - Pyridinecarbonitrile,5 - hydroxy - (9cl)
    Molecular Formula C6H4N2O
    Molecular Weight 120.11 g/mol
    Appearance Solid (predicted)
    Boiling Point 343.3 °C at 760 mmHg (predicted)
    Melting Point 213 - 217 °C
    Density 1.33 g/cm³ (predicted)
    Solubility Soluble in organic solvents (estimated)
    Pka 4.92 (predicted)
    Logp -0.07 (predicted)
    Refractive Index 1.613 (predicted)

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    Frequently Asked Questions

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    3-Pyridinecarbonitrile, what are the chemical properties of 5-hydroxy- (9cl)
    3-Pyridinecarbonitrile, 5-hydroxy- (9cl), this is an organic compound. Its chemical properties are unique and diverse.
    In terms of physical properties, this compound is in a specific form under normal conditions, either solid or liquid, depending on the temperature and pressure of the surrounding environment. Its melting point, boiling point and other physical parameters are crucial for the identification and separation of this substance. The melting point is related to the temperature at which it changes from solid to liquid, and the boiling point is related to the conditions for the conversion of liquid to gaseous.
    In terms of chemical properties, the presence of 5-hydroxyl gives the compound a certain hydrophilicity. Hydroxyl groups are active chemically active groups and are prone to participate in many chemical reactions. For example, it can be esterified with acids to form corresponding ester compounds. During this reaction, the hydrogen atom of the hydroxyl group is combined with the hydroxyl group in the carboxyl group of the acid to form water, and the remaining part is connected to form an ester.
    In addition, the cyanyl group of the 3-pyridyl formonitrile part also has considerable chemical activity. Cyanyl groups can undergo hydrolysis under specific conditions, convert to carboxyl groups, or undergo addition reactions with nucleophiles, and derive various compounds. This makes the substance have a wide range of application potential in the field of organic synthesis, and can be used as a key intermediate to prepare more complex organic compounds.
    In addition, the chemical stability of the compound is also affected by the molecular structure. The conjugate system of the pyridine ring provides certain stability for the molecule, but the activity of the hydroxyl group and the cyano group makes it prone to chemical reactions under certain conditions. This mutual check and balance relationship determines its chemical behavior in different environments.
    3-Pyridinecarbonitrile, what are the main uses of 5-hydroxy- (9cl)
    3-Pyridyl methylonitrile, 5-hydroxy- (9cl), this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize drugs with specific biological activities. Due to the characteristics of molecular structure, it can participate in a variety of chemical reactions, providing a framework for the creation of new drug molecules. For example, it may be used to construct pyridine drugs with unique pharmacological effects for the treatment of diseases such as inflammation and cardiovascular diseases.
    In the field of materials science, it also has outstanding performance. It can be used as a synthetic raw material for functional materials, and materials with special properties can be prepared through chemical modification and polymerization. For example, it may be able to synthesize polymer materials with good optical or electrical properties, which can be used in optoelectronic devices, sensors, etc. Due to the presence of nitrile and hydroxyl groups in its structure, it endows the material with diverse reaction check points and physicochemical properties, thereby improving material properties.
    In the field of organic synthetic chemistry, it plays an important role. As a multi-functional synthetic block, it can participate in many classical organic reactions, such as nucleophilic substitution reactions, addition reactions, etc. Through ingenious design of reaction paths, it can be used to construct complex organic molecular structures, expand the variety and structural diversity of organic compounds, and provide a key material basis for the development of organic synthetic chemistry.
    3-Pyridinecarbonitrile, what are the synthesis methods of 5-hydroxy- (9cl)
    In order to prepare 3-pyridyl methylonitrile, 5-hydroxy- (9cl), the following ancient method can be used. First, take the pyridine as the group, which is often the key starting material in organic synthesis.
    The first step is to hydroxylate the pyridine. Under mild reaction conditions, the 5-position of the pyridine is introduced into the hydroxyl group with an appropriate phenolizing agent. This step requires fine regulation of the reaction temperature, time and reagent dosage. If the temperature is too high or side reactions occur, if it is too low, the reaction will be delayed. Time control is also critical. If the reaction is short, the reaction will not be completed, and if it is long, there may be a risk of overreaction.
    Next, the obtained 5-hydroxypyridine is converted into the corresponding nitrile compound. By halogenation, the appropriate position of 5-hydroxypyridine can be halogenated first, and then the cyanide reagent can be used instead to introduce the nitrile group. The halogenation step requires the selection of a suitable halogenating agent to consider its activity and selectivity. At the time of cyanidation, the nature of the cyanide reagent and the polarity of the reaction solvent are all related to the success or failure of the reaction.
    Or, the nitrile group is introduced to the pyridine first, and then the hydroxylation is performed. However, this path may need to deal with the influence of the nitrile group on the subsequent hydroxylation reaction, because the nitrile group has electron-absorbing properties, or changes the electron cloud distribution of the compound, which affects the check point and rate of hydroxylation.
    During the synthesis process, the choice of solvent is also important. Polar solvents or ionic reactions, non-polar solvents are suitable for some nucleophilic substitutions and other reactions. After each step of the reaction, suitable separation and purification methods, such as distillation, recrystallization, column chromatography, etc., are required to obtain pure products to facilitate the next step of the reaction. In this way, after multiple steps of delicate operation, 3-pyridinonitrile, 5-hydroxy- (9cl) can be obtained.
    3-Pyridinecarbonitrile, what is the price range of 5-hydroxy- (9cl) in the market?
    I look at your question, but I am inquiring about the market price range of 3-pyridyl methanonitrile, 5-hydroxy- (9cl). However, the price of this chemical substance often changes due to multiple reasons, and it is difficult to determine an exact number.
    First, the preparation is difficult and easy. If the preparation requires difficult methods and rare materials, the price will be high; on the contrary, if the preparation is simple and the raw materials are easily available, the price will be low. Second, the market supply and demand situation, if there are many people in need and few people in supply, the price will rise; if the supply exceeds the demand, the price will decline. Third, the quality is good or bad, those with high purity and high quality will be higher than those with ordinary prices.
    And because I have not been involved in the commercial market, it is difficult to know the real-time price. However, if you want to get the actual price, you can visit the chemical raw material supplier, or consult the chemical trading platform, where you may be able to tell you a more accurate price range. Although the price has not been explicitly stated, I hope this will inspire you to know the impact of the price and help you find what you need.
    3-Pyridinecarbonitrile, what are the storage conditions for 5-hydroxy- (9cl)?
    3-Pyridinecarbonitrile, 5-hydroxy- (9cl), this is a special chemical substance. Its storage conditions are crucial, related to the stability and effectiveness of the substance.
    According to chemical principles, such substances should be stored in a cool, dry and well-ventilated place. A cool environment can slow down its chemical reaction rate and avoid decomposition or deterioration of substances due to excessive temperature. Dry places can prevent moisture, because moisture is often the medium of many chemical reactions, it can cause adverse reactions such as hydrolysis. Well ventilated, it can disperse harmful gases that may be generated in time to ensure the safety of the storage environment.
    Furthermore, it should be stored separately from oxidants, acids, bases and other substances. This may even cause danger due to the chemical properties of the substance, or violent reactions with the above categories of substances. If the oxidizing agent has strong oxidizing properties, or an oxidation reaction occurs with the substance; acid-base substances may also undergo acid-base neutralization or other chemical reactions with it, which will damage their quality.
    When storing, you should also pay attention to the choice of containers. It is advisable to use well-sealed containers to prevent the substance from evaporating or reacting with the external environment. And the material of the container must be compatible with the substance, do not chemically react with it, and ensure the purity and stability of the substance.
    In daily management, the storage environment and material status should be regularly checked. Examine whether there are any abnormalities such as deterioration or leakage, and if so, deal with them in a timely manner to ensure the safety of storage and the availability of materials.