3-pyridinecarbonitrile, 2-(trifluoromethyl)-

The physical properties of 3-aminopropionic acid, 2- (triethylmethyl) -, and the physical properties of 3-aminopropionic acid are derived from its chemical properties. Each of these two has its own characteristics, and its molecules are dense.
First 3-aminopropionic acid, which is a compound containing an amino carboxyl group. It has properties, which can not only react to acids, but also act. The amino group is acidic, and the carboxyl group is acidic. This property makes 3-aminopropionic acid exist in different sub-forms at different pH environments. In aqueous solutions, it can be balanced according to the acidity of the solution. In addition, due to the carboxyl group, it can be esterified and reactive, and the alcohol can be catalyzed to form an ester compound; the amino group can also be aminated and reactive, and the acid or anhydride can be reactive to form an amide. This reaction is very important in the synthesis.
to 2- (triethylmethyl), from which it can be seen that it is dominated by a carbon skeleton and has three ethyl groups. This makes it have a certain lipid solubility and high solubility in the solution. Due to the sub-effect of the alkyl group, the molecular cloud composition of the alkyl group is changed, which affects its chemical activity. Generally speaking, the increase of alkyl groups can increase the quality of the molecule. However, due to the increase in carbon, the molecular force increases, and the melting temperature also increases. The reactive phase is low, and the main reactive phase is free radical substitution, because the atom on the alkyl group can be substituted under specific reactive components.
In other words, 3-aminopropionic acid has reactive and reactive properties due to its special functional properties; 2- (triethylmethyl) due to its carbon skeleton, alkyl, has the properties of fat solubility, phase determination, and specific reactive properties.

The chemical properties of 3-aminopropyl alcohol, 2- (triethylamino) -are as follows:
This substance contains functional groups such as amino groups and alcohol hydroxyl groups, so it has certain alkalinity and nucleophilicity.
Its basicity is derived from the amino group. The nitrogen atom in the amino group has a pair of lone pair electrons, which can bind protons and exhibit the characteristics of bases. In some acidic environments, it can react with acids to form salts. For example, when reacting with hydrochloric acid, the amino group will combine with hydrogen ions to form the corresponding ammonium salt, which reflects its alkalinity.
In terms of nucleophilicity, the lone pair electrons of the amino group enable it to attack some electrophilic reagents. For example, in a nucleophilic substitution reaction, if a suitable halogenated hydrocarbon is present, the nitrogen atom of the amino group can be used as a nucleophilic reagent to attack the carbon atom connected to the halogen in the halogenated hydrocarbon, and the halogen atom leaves to form a new nitrogen-containing compound.
The alcohol hydroxyl group also imparts some chemical properties to the substance. The hydroxyl group can undergo a substitution reaction, such as with hydrogen halide, the hydroxyl group will be replaced by the halogen atom to form halogenated hydrocarbons. At the same time, the hydroxyl group can also participate in the esterification reaction. Under the condition of acid catalysis, it reacts with carboxylic acids to form esters and water.
In addition, because the substance contains multiple carbon chain structures, it has certain solubility characteristics. In polar solvents, because it contains polar groups amino and hydroxyl, there will be a certain solubility; in non-polar solvents, the solubility is relatively small. Moreover, hydrogen bonds can be formed between its molecules, which affects its melting point and other physical properties, resulting in a relatively high melting point.

3-Aminopropanol, 2- (triethylmethyl) - is mainly used in many chemical and pharmaceutical fields.
In the chemical industry, it is an important intermediate in organic synthesis. It can participate in the preparation of many organic compounds, such as the synthesis of alcohol derivatives with special structures. With its reactivity of amino and hydroxyl groups, it can react with different reagents to build a variety of complex organic molecular structures, laying the foundation for the development of new materials and the synthesis of fine chemicals. For example, when preparing some polymer materials with special properties, it can be introduced as monomers or modifiers to endow the materials with unique physical and chemical properties.
In the field of medicine, its value should not be underestimated. Often used as a key raw material for drug synthesis. Due to its structure having a certain biological activity basis, it can be chemically modified into drug molecules with specific pharmacological effects. For example, in the synthesis of some nervous system drugs and cardiovascular system drugs, 3-aminopropanol, 2- (triethylmethyl) - can be used as starting materials or key intermediates. Through a series of reaction steps, a drug structure that meets pharmacological requirements can be precisely constructed, which can help improve drug efficacy and reduce side effects. In addition, in the early stages of drug development, the optimization of lead compounds based on the structure of this compound provides the possibility for the development of new and efficient drugs.

To prepare 3-aminopropionic acid and 2 - (triethylmethyl), there are various methods, which are described by Jun Chen today.
First, the synthesis of 3-aminopropionic acid. First, it can be prepared by the addition reaction of acrylic acid and ammonia. Acrylic acid has the activity of ethylenically bonding, and ammonia is a nucleophilic reagent. Under suitable temperature, pressure and catalyst conditions, the nitrogen atom of ammonia adds to the double bond of acrylic acid to obtain 3-aminopropionic acid. The raw materials are easy to obtain and the reaction is relatively straight. However, attention should be paid to the control of the reaction conditions to increase the yield and purity of the product. < Br >
Second, diethyl malonate is used as the starting material. First, it is alkylated with halogenated hydrocarbons, and a suitable substituent is introduced. After hydrolysis, decarboxylation and other series of reactions, 3-aminopropionic acid is finally obtained. Although this path is a little complicated, it has flexibility in the introduction and conversion of functional groups, and can fine-tune the structure of the product according to the needs.
As for the synthesis of 2 - (triethylmethyl). Often react with triethylmethyl lithium reagents with suitable halogenated hydrocarbons. The halogen atom of halogenated hydrocarbons has good departure properties, while triethylmethyl lithium is a strong nucleophilic reagent. When the two meet, the nucleophilic substitution reaction occurs immediately, and the halogen atom is replaced by triethylmethyl to obtain the target product. This reaction needs to be carried out under the harsh conditions of anhydrous and anaerobic, because triethylmethyl lithium has high activity and is easy to react with water and oxygen, which affects the formation of the product.
It can also be reacted with triethylmethyl Grignard reagent with aldehyde or ketone. The carbonyl of aldehyde and ketone is electrophilic, and the carbon anion of triethylmethyl Grignard reagent is strongly nucleophilic. After nucleophilic addition, hydrolysis and other treatments can also produce 2- (triethylmethyl). In this way, the substrates of aldehyde and ketone need to be carefully selected, and the post-reaction treatment is also required to achieve the ideal synthesis effect.

3 - to its methyl ether, 2 - (triethylmethyl) - during storage and transportation, you need to pay attention to everything to ensure that it is safe.
Both of these are chemical substances with unique properties. When storing, you should first choose a cool, dry and well-ventilated place. Cover its nature or volatile, or afraid of moisture, if it is in a warm and humid place, it may change, damage its quality, or even cause danger. Such as 3 - to its methyl ether, with a certain degree of volatility, in a high temperature environment, the volatilization intensifies, not only causing material loss, but also volatile gas or mixed with air, into an explosive mixture, in case of open flame, static electricity, etc., it is easy to cause deflagration disaster.
Furthermore, the storage place should be away from fire sources, heat sources and oxidants. 2 - (triethylmethyl) in case of oxidant, or a violent chemical reaction, causing serious consequences such as combustion and explosion. And both should be stored separately with other chemicals to prevent interaction and unexpected changes.
As for transportation, it is necessary to use suitable appliances. Make sure that the appliance is well sealed to prevent its leakage. During transportation, the traffic should be stable to avoid bumps and sudden brakes, so as to avoid package damage and material leakage due to external forces. And the transporter must be familiar with the characteristics of these two things and know emergency methods. In case of leakage, do not panic, and deal with it quickly according to the established policies. Evacuate the crowd first, prohibit fireworks, and then take corresponding measures as appropriate. Such as covering it with sand, adsorbing the leakage, and properly collecting and handling it. Do not let it flow freely, so as not to pollute the environment and endanger the safety of everyone.
All of these are important things that should not be ignored when storing and transporting 3-to-methyl ether and 2- (triethyl methyl). Be sure to do it carefully to ensure safety.