3 Pyridinecarbonitrile 2 Methoxy 4 Methyl 9ci
pyridine pyrrole pyrazine piperidine piperazine

3-Pyridinecarbonitrile,2-methoxy-4-methyl-(9CI)

    Specifications

    HS Code

    248037

    Chemical Formula C9H8N2O
    Molecular Weight 160.17
    Iupac Name 2 - methoxy - 4 - methylnicotinonitrile
    Physical State At Standard Conditions Solid (usually)
    Solubility In Water Low, likely less than 1 g/L due to its non - polar aromatic and nitrile groups
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane, and acetone

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    Frequently Asked Questions

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    3-Pyridinecarbonitrile, what are the chemical properties of 2-methoxy-4-methyl- (9CI)
    3-Pyridineformonitrile, 2-methoxy-4-methyl- (9CI), is one of the organic compounds. Among its physical properties, it is mostly solid at room temperature, and the color is white or nearly colorless, with a certain crystalline form. The melting point is very critical. The melting point is in a specific temperature range. This temperature causes the substance to change from solid to liquid, while the boiling point is related to the conditions for liquid to gaseous state, which are determined by factors such as intermolecular forces.
    In terms of solubility, it may have a certain solubility in organic solvents such as ethanol and ether. Because its molecular structure contains polar and non-polar parts, it can form interactions with organic solvent molecules such as van der Waals force and hydrogen bonds. However, the solubility in water may be limited, because the polarity matching of water molecules and the polarity of the compound is not perfect.
    In the chemical properties, the cyanyl group has high activity and can participate in many reactions. For example, in the hydrolysis reaction, the cyanyl group can be gradually converted into carboxyl groups under the catalysis of acids or bases to generate corresponding pyridine carboxylic acid derivatives. This reaction mechanism is complex and involves steps such as nucleophilic addition and elimination.
    Methoxy, as a donating group, has a significant impact on the electron cloud density distribution of the pyridine ring, which increases the electron cloud density at a specific position of the pyridine ring. In the electrophilic substitution reaction, this position is more susceptible to the attack of electrophilic reagents, resulting in selective changes in the reaction area.
    methyl also affects the electronic structure of the pyridine ring due to the superconjugation effect, and affects the molecular steric resistance. In the redox reaction, the compound may exhibit unique reactivity due to the characteristics of the pyridine ring and substituents, or be oxidized to higher valence oxides, or under the action of suitable reducing agents, cyano and other groups are reduced to form amine and other derivatives.
    In summary, 3-pyridineformonitrile, 2-methoxy-4-methyl- (9CI) has potential application value in organic synthesis and other fields due to its special structure, physical and chemical properties.
    3-Pyridinecarbonitrile, what are the preparation methods of 2-methoxy-4-methyl- (9CI)
    The method of preparing 2-methoxy-4-methyl-3-pyridineformonitrile (3-Pyridinecarbonitrile, 2-methoxy-4-methyl- (9CI)) depends on the technique of organic synthesis. The following is a common method, and it is said in ancient Chinese:
    First, the corresponding pyridine derivative can be used as the starting point. Select the appropriate 2-hydroxy-4-methylpyridine, methoxylate reaction, with iodomethane or dimethyl sulfate as the methylation agent, and catalyze by bases, such as potassium carbonate, sodium hydroxide, etc., to convert the hydroxyl group to methoxy group. Then, a cyanyl group is introduced at the 3-position of the pyridine ring. In this step, a suitable cyanide reagent, such as cuprous cyanide, trimethylsilyl cyanide, etc., can be used to introduce a cyanyl group after nucleophilic substitution or other related reactions under suitable reaction conditions, and the final target product is obtained.
    Second, other compounds containing pyridine structures are also used as starting materials. If a pyridine halide with a suitable substituent is selected, it is first methoxylated and then cyanized. In the nucleophilic substitution reaction of the halide, the halogen atom can be replaced by a methoxy group or a cyanyl group. When methoxylating, choose a nucleophilic methoxy reagent; when cyanizing, also according to the reaction characteristics, choose the appropriate cyanide agent and reaction conditions, so that the reaction can be carried out in an orderly manner, and finally 2-methoxy-4-methyl-3-pyridineformonitrile is obtained.
    When preparing, pay attention to the control of the reaction conditions. Temperature, reaction time, reagent dosage ratio, etc., all have a great impact on the reaction process and product yield. If the temperature is too high, side reactions may breed; improper reagent ratio, or incomplete reaction. Therefore, during the experiment, it is often necessary to fine-tune and find the best reaction conditions according to different reaction characteristics in order to achieve the purpose of efficient preparation of the target product.
    3-Pyridinecarbonitrile, 2-methoxy-4-methyl- (9CI) is used in what fields
    3-Pyridyl formonitrile, 2-methoxy-4-methyl- (9CI), this compound has important applications in the fields of pharmaceutical synthesis, material chemistry, and pesticide research and development.
    In the field of pharmaceutical synthesis, due to its unique structure, it may be used as a key intermediate. The combination of pyridyl ring and methoxy, methyl and cyano groups endows it with specific chemical activity and spatial configuration. After chemical modification, it can construct structures that fit biological targets and develop new drugs. For example, it may be possible to optimize the interaction with specific enzymes or receptors by adjusting its substituents, providing new directions for the creation of anti-cancer and anti-infective drugs.
    In terms of material chemistry, due to its good stability and electronic properties, it can be used to prepare organic optoelectronic materials. Pyridine ring conjugated system is synergistic with methoxy power supply and cyanyl power absorption, or affects the optical and electrical properties of materials. Such as for organic Light Emitting Diode (OLED), or to improve the luminous efficiency and stability; for solar cells, or to enhance the ability of light absorption and charge transfer, and improve the photoelectric conversion efficiency of batteries.
    In the field of pesticide research and development, its structural characteristics may endow compounds with biological activities. or have inhibitory or killing effects on certain pests and pathogens, and develop new pesticides. By modifying the substituents, the lipophilicity, water solubility and biological activity of the compounds can be adjusted, the targeting and sustainability of pesticides can be improved, and the impact on the environment can be reduced, providing a basis for the creation of green pesticides.
    In summary, 3-pyridineformonitrile, 2-methoxy-4-methyl- (9CI) have shown broad application prospects in many fields, which is of great significance to promoting technological innovation and development in related fields.
    3-Pyridinecarbonitrile, what is the market price of 2-methoxy-4-methyl- (9CI)
    I don't know what the price of "3 - Pyridinecarbonitrile, 2 - methoxy - 4 - methyl - (9CI) " is in the market. The price of the city often varies according to the situation of time, place, quality and supply and demand. This chemical product may be sought in chemical workshops and pharmaceutical shops. If you want to know its exact price, you must visit various market shops and consult merchants before you can get it. Or you can go online and find the market exchange platform of chemical materials, and observe the change of its price in detail. Or you can visit various chemical industry conferences, seminar gatherings, and discuss with the industry, and then you can know the approximate price. However, this is not a definite number, it is only a way of seeking, and if you want to get the true price, you must experience the path of exploration.
    3-Pyridinecarbonitrile, what are the storage conditions for 2-methoxy-4-methyl- (9CI)?
    What are the storage conditions for 3-pyridineformonitrile, 2-methoxy-4-methyl- (9CI)? This is an important matter related to the preservation of chemical substances and must not be ignored.
    When storing this substance, it should first be placed in a cool place. Because of the cool place, the temperature is relatively low, which can slow down the rate of its chemical reaction and prevent it from changing its properties due to excessive temperature. If exposed to high temperature, it may cause adverse reactions such as decomposition and polymerization, which will damage its inherent chemical properties.
    and must be placed in a dry place. Moisture is the enemy of many chemicals, and this substance is no exception. Moisture may cause reactions such as hydrolysis, causing damage to its chemical structure and quality. Therefore, it is crucial to choose a dry place to avoid moisture erosion.
    Furthermore, it should be placed in a well-ventilated place. Good ventilation can dissipate harmful gases that may be generated, and prevent them from accumulating in a closed space and causing danger. It can also maintain the freshness of the stored ambient air and keep the stability of this material.
    It should also be noted that it should be kept away from fires and heat sources. This substance may be flammable or chemically active, and in case of open flames, hot topics, or cause serious accidents such as combustion and explosion, it will endanger safety. When
    is stored, it should also be stored separately from oxidizing agents, acids, bases and other substances. Because these substances may react violently with 3-pyridyl formonitrile, 2-methoxy-4-methyl- (9CI), causing danger.
    Storage places should have suitable materials to contain substances that may leak, in case of leakage, and can be properly handled in time to prevent their spread and cause greater harm. In this way, comprehensive storage conditions can ensure the stability and safety of this chemical substance.