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3-pyridinecarbonitrile, what is the chemistry of 2-amino-5-iodo-4-methyl-?
3-Pyridinecarbonitrile, 2-amino-5-iodine-4-methyl, this is an organic compound. Its chemical properties are unique, let me explain in detail for you.
From the structural point of view, the pyridine ring is its core structure, and the nitrile group (-CN) is connected to the third position of the pyridine ring. This nitrile group is active and electrophilic, and can participate in many reactions, such as hydrolysis, and can be converted into carboxyl groups (-COOH). Under suitable conditions, it can also undergo addition reactions with nucleophiles. < Br >
2-Amino is attached to the second position of the pyridine ring. The amino group is basic and can accept protons because the nitrogen atom has a lone pair of electrons. This basic property enables the compound to react with acids to form salts. In organic synthesis, the amino group is often a check point for reaction and can participate in reactions such as substitution and condensation.
5-Iodine atom is attached to the fifth position of the pyridine ring. The iodine atom is relatively large and has a certain electronegativity. In compounds, the molecular polarity is changed, and because the C-I bond energy is relatively small, the iodine atom is easier to leave, so it can be used as a good leaving group for nucleophilic substitution reactions and participate in many reactions to construct new carbon-carbon bonds or carbon-heterozygous bonds.
4-methyl is attached to the fourth position of the pyridine ring, and methyl is the power supply group, which can affect the electron cloud density distribution on the pyridine ring through induction effect, and then affect the reactivity of each substituent. Overall, the compound exhibits diverse chemical properties due to the interaction of various groups, which may have potential application value in the field of organic synthesis and can be used as a key intermediate to participate in the construction of complex organic molecules.
3-pyridinecarbonitrile, what are the main uses of 2-amino-5-iodo-4-methyl-
3-Pyridineformonitrile, 2-amino-5-iodine-4-methyl This substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate for the synthesis of many specific drugs. Its structural properties enable it to participate in specific chemical reactions and help build molecular structures with unique pharmacological activities, which is of great significance for the development of drugs for the treatment of difficult diseases.
In the field of materials science, it also has outstanding performance. Due to its special chemical composition and structure, it may contribute to the preparation of new functional materials. It may endow materials with unique optical and electrical properties, providing the possibility for the development of new optoelectronic materials, semiconductor materials, etc.
In organic synthetic chemistry, it plays an indispensable role. As an important synthetic building block, it can build complex and novel organic molecular structures with the help of diverse organic reactions, expand the variety and application range of organic compounds, and promote organic synthetic chemistry to new heights, laying a solid foundation for the development of many fields.
3-pyridinecarbonitrile, what is 2-amino-5-iodo-4-methyl- synthesis method?
The method of preparing 2-amino-5-iodine-4-methyl-3-pyrimethanonitrile can be carried out according to the following steps.
First, use a suitable starting material, such as 4-methyl-3-pyrimethanonitrile as a group. To introduce amino and iodine atoms into this compound, it needs to be carried out in a step-by-step and orderly manner.
First, 4-methyl-3-pyrimethanonitrile undergoes an amination reaction. Alternatively, use a suitable amination reagent, such as liquid ammonia, to interact with the catalyst. In a specific reaction vessel, control the temperature and pressure conditions. The temperature may be maintained within a certain range, such as between 50 ° C and 80 ° C, and the pressure is also adjusted to an appropriate value, about 1-3 MPa. In this environment, the amination reagent reacts fully with 4-methyl-3-pyridineformonitrile, and after a certain period of time, such as 12 to 24 hours, the ortho-nitrile is introduced into the amino group to form 2-amino-4-methyl-3-pyridineformonitrile.
Then the obtained 2-amino-4-methyl-3-pyridineformonitrile is iodized. Select a suitable iodizing reagent, such as iodine elemental with a suitable oxidizing agent, such as hydrogen peroxide. In an organic solvent, such as dichloromethane, in a low temperature environment, about 0 ° C to 10 ° C, slowly add the iodizing reagent dropwise, and closely monitor the reaction process. After several hours of reaction, such as 3 to 6 hours, the amino group is successfully introduced into the iodine atom, and the final target product is 2-amino-5-iodine-4-methyl-3-pyridinonitrile. After the reaction is completed, the pure product is obtained by separation and purification methods, such as column chromatography or recrystallization. In this way, according to the above steps and conditions, the synthesis of this compound can be achieved.
3-pyridinecarbonitrile, what is the price range of 2-amino-5-iodo-4-methyl- in the market?
I look at your question, but I am inquiring about the market price range of 2-amino-5-iodine-4-methyl-3-pyridylmethanonitrile. However, the price of this product in the market often varies due to many factors, and it is difficult to determine the exact number.
First, the source of production is different. Different origins have different raw material costs and processes, resulting in poor prices. If it is produced in a place with exquisite craftsmanship and convenient raw materials, the price may be more appropriate; if it is produced in a place with difficult conditions and scarce raw materials, the price will increase.
Second, purity is crucial. For those with high purity, the preparation is difficult, time-consuming and laborious, and the cost is high, and the price is high; for those with low purity, the preparation is slightly easier, the cost is slightly lower, and the price is relatively low.
Third, market supply and demand. If there are many people who want this product, but there are few people who supply it, according to the rules of the market, the price will rise; if the supply exceeds the demand, the merchant will sell its goods, and the price may drop.
Fourth, the number of transactions also has an impact. If you buy in bulk, the merchant may offer a preferential price for promoting the quantity; if you only buy a small amount, the price may not be excellent, or even higher.
As far as I know, the price of this product in the market may be between tens of yuan and hundreds of yuan per gram. However, this is only a rough estimate. The actual price needs to be consulted in detail with chemical raw material suppliers, reagent sellers, etc. After multiple comparisons and inquiries, a more accurate price range can be obtained.
3-pyridinecarbonitrile, what are the relevant safety precautions for 2-amino-5-iodo-4-methyl-?
3-Pyridineformonitrile, 2-amino-5-iodine-4-methyl This substance is a matter of safety and must be treated with caution.
First, this substance is a chemically synthesized substance, which is mostly involved in fine chemicals, pharmaceutical synthesis and other fields. When operating, be sure to wear appropriate protective equipment, such as protective gloves, goggles, protective clothing, etc. Because it may be irritating to the skin, eyes, respiratory tract, etc., a little inadvertent contact may cause discomfort or even damage. For example, protective gloves must be made of chemically resistant materials to effectively resist their damage; goggles should also ensure a clear field of vision and a good seal to prevent them from splashing into the eyes.
Second, in terms of storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources, because it has certain chemical activity, high temperature, humid environment or its chemical properties change, causing danger. And it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to avoid chemical reactions and accidents.
Third, during use, strictly follow the established operating procedures. It is best to operate in a fume hood, so that volatile gas can be discharged in time and the concentration of harmful substances in the air can be reduced. If a leak occurs accidentally, do not panic, and quickly evacuate unrelated personnel and isolate the leakage area. When a small amount leaks, it can be absorbed by inert materials such as sand and vermiculite; if a large amount leaks, it needs to be built a dike or dug for containment, and transferred to a special collector with an explosion-proof pump for proper disposal.
Fourth, dispose of this waste, and must not be discarded at will. It should be handed over to a professional and qualified treatment institution in accordance with relevant regulations. Because it may contain heavy metal iodine and other chemical groups, it can be discarded or infiltrated into soil and water sources at will, endangering the ecological environment and causing endless harm.
In short, the treatment of 3-pyridinonitrile, 2-amino-5-iodine-4-methyl, from operation, storage, use to disposal, must adhere to strict regulations and cannot be slack in order to ensure safety.