3-Pyridinecarbonitrile, 2-[4-[2-[[(2S)-2-hydroxy-3-[2-(2-thienyl)phenoxy]propyl]amino]-2-methylpropyl]phenoxy]-

There is a substance called 3 - Pyridinecarbonitrile, 2 - [4 - [2 - [[ (2S) -2 - hydroxy - 3 - [2 - (2 - thienyl) phenoxy] propyl] amino] -2 - methylpropyl] phenoxy]. The chemical structure of this substance is quite complex.
In its structure, the pyridine formonitrile part, the pyridine ring is a six-membered nitrogen-containing heterocycle, and the nitrile group (-CN) is connected to the third position of the pyridine ring. On the other side, there is a complex long chain. This long chain starts from the phenoxy group, and the fourth position of the phenyl ring is connected to a specific structure. Among them, it also contains 2- [2- [[ (2S) -2 -hydroxy-3- [2- (2-thiophenyl) phenoxy] propyl] amino] -2 -methylpropyl].
(2S) -2 -hydroxy-3- [2- (2-thiophenyl) phenoxy] propyl moiety, chiral center, S configuration, hydroxyl group is connected to propyl group containing thiophenyl phenoxy group. 2-methylpropyl group forms a complex whole together with the above structure and is connected by amino group. Overall, this chemical structure fuses multiple functional groups and cyclic structures, which are interconnected to form a unique chemical structure.

This substance is 2- [4- [2- [[ (2S) -2 -hydroxy-3- [2- (2 -thiophenyl) phenoxy] propyl] amino] -2 -methylpropyl] phenoxy] -3 -pyridineformonitrile. Its main physical properties are as follows:
This compound is usually in solid form and has a certain melting point, but the specific melting point value needs to be accurately determined by experiments. Different preparation processes and purity may affect its melting point. In terms of solubility, its dissolution in organic solvents is more significant. In view of the fact that its molecular structure contains hydrophobic groups such as pyridine ring, benzene ring and thiophene group, it should have good solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF). However, due to the presence of hydrophilic hydroxyl groups in the molecule, it may also have a certain weak solubility in water, but its solubility in water is necessarily lower than that of organic solvents.
The density of this substance depends on its crystal accumulation mode and intermolecular forces. Due to the relatively complex molecular structure, there are various interactions between molecules, including van der Waals force, hydrogen bond, etc., which affect its density. Before actual measurement, it is difficult to accurately estimate its specific value. In terms of stability, given the bond energy of each chemical bond in the molecule, it is relatively stable under conventional conditions. However, under extreme conditions such as strong acids, strong bases or high temperatures and strong oxidants, some chemical bonds in the molecule may break or react. For example, hydroxyl groups may be protonated under acidic conditions, which in turn affects the overall properties of the molecule; nitrile groups on the pyridine ring may undergo reactions such as hydrolysis under specific conditions.

This substance is 3 - Pyridinecarbonitrile, 2 - [4 - [2 - [[ (2S) -2 - hydroxy - 3 - [2 - (2 - thienyl) phenoxy] propyl] amino] -2 - methylpropyl] phenoxy], and its common uses involve the field of pharmaceutical chemistry.
The structure of this substance contains specific pyridinonitrile and complex phenoxy side chains. In the way of pharmaceutical research and development, or because of its unique structure, it can be compatible with specific targets in organisms, just like mortise and tenon. Or as a receptor antagonist, blocking specific signal transduction pathways to regulate physiological processes, such as the relevant regulation of the nervous system and cardiovascular system. < Br >
In the process of organic synthesis, it can be a key intermediate. If it is based on it, through delicate reactions, various functional groups are added, various compounds are derived, and the library of organic molecules is expanded, paving the way for the subsequent exploration of new active substances. Its research in medicinal chemistry is like the key to unlocking unknown treasures, leading the journey of exploring new therapies and new medicines.

To prepare this 2- [4- [2- [[ (2S) -2 -hydroxy-3- [2- (2-thiophenyl) phenoxy] propyl] amino] -2 -methylpropyl] phenoxy] -3 -pyridineformonitrile product, there are many methods.
First, it can be synthesized step by step. First, take a suitable starting material, start with 2- (2-thiophenyl) phenol, and make it undergo nucleophilic substitution reaction with a suitable halogenated propanol derivative under alkali catalysis to form an alcohol intermediate containing thiophenylphenoxy. This step requires selecting a suitable base, such as potassium carbonate, etc., in a suitable organic solvent, heating to promote the reaction. The reaction time depends on the monitoring of the reaction process, or it takes several hours.
Subsequently, this intermediate is reacted with 2-methyl-2-aminopropanol under the action of a condensing agent to form a key amino alcohol intermediate. The condensing agent can be selected as dicyclohexyl carbodiimide (DCC), etc. It also takes a long time or a whole day to react at a mild temperature to ensure the complete reaction.
Finally, this key intermediate is reacted with 2-halo-3-pyridineformonitrile under alkaline conditions to obtain the target product. This step of alkali can be selected from strong bases such as sodium hydride, which can be reacted in an anhydrous and anaerobic environment. The reaction conditions are harsh and need to be carefully controlled.
Second, it can also be synthesized by one-pot method. Several starting materials are mixed in a certain proportion, and the target product is synthesized in one step under suitable catalysts and reaction conditions. Although this method is simple, it requires higher reaction conditions. It requires precise regulation of factors such as catalyst dosage, reaction temperature and time to improve the yield of the product. It may take a lot of time to repeatedly test and explore the best reaction parameters.

This is a compound named 2 - [4 - [2 - [[ (2S) -2 -hydroxy-3- [2 - (2 - thiophenyl) phenoxy] propyl] amino] -2 -methylpropyl] phenoxy] -3 -pyridineformonitrile. During use, the following things should be noted:
First, safety protection must not be ignored. The characteristics or health risks of this compound must be worn when operating, such as gloves, goggles and protective clothing to prevent it from contacting the skin and eyes, and to avoid inhalation of dust or fumes. In case of accidental contact, rinse with a large amount of water immediately and seek medical treatment according to the specific situation.
Second, storage conditions are crucial. It needs to be stored in a cool, dry and well-ventilated place, away from fire, heat and incompatible substances. Due to its chemical properties, improper storage or deterioration and decomposition can affect the use effect and even cause safety accidents.
Third, accurate weighing and operation cannot be ignored. When using, precise instruments should be used for weighing to ensure that the dosage is correct. Strict procedures should be followed during operation to prevent abnormal chemical reactions caused by improper operation and affect experimental or production results.
Fourth, waste disposal should also be in compliance. After use, the remaining compounds and related waste should not be discarded at will. They should be properly disposed of in accordance with local regulations and environmental protection requirements to prevent environmental pollution.