3-Nitro-4-methylpyridine

3-Nitro-4-methylpyridine is also an organic compound. It has various physical properties, which are detailed below.
In terms of its appearance, under room temperature and pressure, it is a light yellow to brown crystalline powder, which can be seen visually. Its melting point is about 57-61 ° C. When the temperature reaches this range, the state of matter gradually melts from the solid state to the liquid state. This phase transition point is its important physical property. The boiling point is around 273.5 ° C. At this high temperature, the substance will transform from a liquid state to a gaseous state, showing the temperature limit of its gas-liquid phase transition.
In terms of solubility, it has good solubility in organic solvents, such as ethanol, ether, etc. This is because the molecular structure of the compound can form a suitable interaction with the molecules of the organic solvent, so it can be soluble. However, in water, its solubility is relatively limited, because the polarity of water is different from the polarity matching of the molecule of the compound, making it difficult to dissolve in water.
The density is about 1.32 g/cm ³, which indicates the mass per unit volume and reflects the compactness of the substance. It also has a certain vapor pressure. Although the vapor pressure is lower at room temperature, the vapor pressure will increase accordingly with the increase of temperature, which is related to its existence in the gas phase.
In addition, 3-nitro-4-methylpyridine has a specific smell. Although it is difficult to describe accurately, it can be smelled to know its unique smell. Its physical properties are of vital significance in chemical research, industrial production and related application fields. It is also the basis for recognizing its properties and using its energy.

3-Nitro-4-methylpyridine is an organic compound with many chemical properties.
This substance is basic because the pyridine ring nitrogen atom has lone pairs of electrons and can accept protons. However, compared with pyridine without nitro substitution, nitro has strong electron absorption, which will reduce the electron cloud density of the pyridine ring and cause its alkalinity to weaken.
The nitro group of 3-Nitro-4-methylpyridine is active and can participate in a variety of reactions. If under appropriate reduction conditions, the nitro group can be reduced to an amino group to obtain 3-amino-4-methylpyridine. This is an important intermediate in organic synthesis and is widely used in medicine, pesticides and other fields.
Its methyl groups are also reactive. Under certain conditions, methyl groups can be oxidized to form functional groups such as carboxyl groups. In addition, methyl groups can participate in alkylation reactions, introducing other alkyl groups to modify the molecular structure and endow the product with different properties.
3 - Nitro - 4 - methylpyridine pyridine ring can undergo electrophilic substitution reaction. However, due to the localization effect of nitro and methyl groups, the substitution reaction check point is selective. Nitro is an meta-locator, methyl is an ortho-and para-locator, and under the combined influence, the electrophilic substitution reaction mainly occurs at specific positions of the pyridine ring, depending on the reaction conditions and the activity of the electrophilic reagents. In conclusion, 3-Nitro-4-methylpyridine is very important in the field of organic synthesis because of its rich chemical properties of nitro and methyl groups.

3-Nitro-4-methylpyridine, Chinese name 3-nitro-4-methylpyridine, is widely used. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, nitrogen atoms coexist with nitro and methyl groups, giving it special chemical activity, can participate in a variety of reactions, and help to construct complex organic molecular structures.
In the field of medicinal chemistry, this is used as a starting material or key intermediate to synthesize many bioactive compounds. After specific reaction modification, the obtained products may have pharmacological activities such as antibacterial, anti-inflammatory and anti-tumor, laying the foundation for the development of new drugs.
In the field of materials science, it also has important uses. It can be chemically converted into polymers or functional materials to improve the electrical, optical or thermal properties of materials, such as the preparation of organic semiconductor materials with special optoelectronic properties.
In pesticide chemistry, it can be used to create new pesticides. Through structural modification and derivatization, pesticide varieties with high inhibition or killing effect on specific pests or pathogens can be synthesized, providing new options for agricultural pest control.
In summary, 3-nitro-4-methylpyridine plays an important role in many fields such as organic synthesis, medicine, materials and pesticides due to its unique chemical properties, promoting technological development and innovation in various fields.

3-Nitro-4-methylpyridine is also an organic compound. The method of its synthesis has been studied by chemists. Here is the method of Chen number.
First, 4-methylpyridine is used as the starting material and is prepared by the technique of nitrification. When 4-methylpyridine encounters a nitrifying agent, such as a mixed acid of concentrated nitric acid and concentrated sulfuric acid, under moderate temperature and pressure, the hydrogen atom on the pyridine ring is replaced by a nitro group, so 3-nitro-4-methylpyridine is obtained. In this process, the temperature is controlled to the core. If it is too high, the side reaction will multiply and the yield will drop; if it is too low, the reaction will be slow and take a long time. < Br >
Second, through the transformation of halogenated pyridine. First halogenate 4-methyl pyridine to obtain halogenated-4-methyl pyridine, and then react with nitrogenation reagents. Halogen atoms have high activity and are easily substituted by nitro groups, so as to obtain the target product. However, the halogenation step needs to select suitable halogenating agents and conditions to avoid the generation of polyhalides.
Third, using pyridine derivatives as raw materials, the structure of 3-nitro-4-methyl pyridine is constructed through multi-step reactions. For example, appropriate substitutions based on pyridine rings are introduced first, and then a series of reactions such as reduction, oxidation, and nitrification are carried out to gradually achieve the goal. Although this approach is complicated, it may have advantages in controlling the purity and selectivity of the product.
All synthesis methods have their own advantages and disadvantages. When used in industrial production or laboratory preparation, it needs to be selected according to many factors such as the availability of raw materials, the level of cost, and the quality and quantity of the product.

3 - Nitro - 4 - methylpyridine is a chemical substance. During storage and transportation, many matters need to be paid attention to.
When storing, choose the first environment. It should be placed in a cool and ventilated warehouse, away from fires and heat sources. This is because it has certain chemical activity, high temperature or open flame is easy to cause danger. The temperature and humidity of the warehouse should be precisely controlled. The temperature should generally not exceed 30 ° C, and the relative humidity should be maintained at 65% - 75% to prevent deterioration.
Furthermore, storage needs to be classified. Do not mix with oxidants, reducing agents, acids, alkalis, etc. Due to its chemical properties, contact with these substances, or react violently, causing fire, explosion and other disasters. And it should be sealed and stored to avoid contact with the air due to moisture, oxygen, etc. in the air or react with it.
When transporting, the packaging must be tight. Select packaging materials that meet safety standards to ensure that there is no leakage during transportation. During handling, it must be lightly loaded and unloaded. Do not drop or heavy pressure to prevent package damage. Transport vehicles should also be properly selected, equipped with fire and explosion-proof facilities, and special vehicles are dedicated, and cannot be mixed with other contraindicated items. Transport personnel should be professionally trained, familiar with the characteristics of the substance and emergency treatment methods, pay close attention to the condition of the goods during transportation, and if there is any leakage and other abnormalities, immediately deal with them according to the plan.