3 Methyl 4 Aminopyridine
pyridine pyrrole pyrazine piperidine piperazine

3-Methyl-4-aminopyridine

    Specifications

    HS Code

    401862

    Name 3 - Methyl - 4 - aminopyridine
    Molecular Formula C6H8N2
    Molecular Weight 108.14 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point 96 - 99 °C
    Boiling Point 251 - 253 °C
    Solubility Soluble in water, alcohols, and some polar organic solvents
    Pka Around 5.3 (for the pyridinium ion formed by protonation of the pyridine nitrogen)
    Flash Point 110 °C
    Density 1.11 g/cm³ (estimated for the solid state)
    Odor May have a characteristic pyridine - like odor

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    Frequently Asked Questions

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    What are the main uses of 3-Methyl-4-aminopyridine?
    3-Methyl-4-aminopyridine is one of the organic compounds. It has a wide range of uses and has important applications in many fields.
    First, in the field of medicine, this compound is a key intermediate for the synthesis of drugs. Because of its unique structure and specific chemical activity, it can be used to create antibacterial, antiviral and anti-tumor drugs. For example, after a series of delicate chemical reactions, it can be used as a starting material to construct molecular structures with unique pharmacological activities, which is expected to become a good medicine for the treatment of difficult diseases.
    Second, in the field of pesticides, 3-methyl-4-aminopyridine is also very popular. With its special chemical properties, high-efficiency, low-toxicity and environmentally friendly pesticides can be prepared. Such pesticides can effectively kill pests, control crop diseases, escort agricultural harvests, and have little harm to the ecological environment.
    In addition, in the field of materials science, it can also play an important role. Or can participate in the preparation of functional polymer materials, endowing materials with special properties such as electrical conductivity and optical activity. On this basis, new materials suitable for electronic devices, optical devices, etc. can be developed to promote the progress of related scientific and technological fields.
    In organic synthetic chemistry, 3-methyl-4-aminopyridine is often an important reagent. Due to its ability to participate in a variety of organic reactions, such as nucleophilic substitution and cyclization, chemists can build complex organic molecular structures, expand the boundaries of organic synthesis, and provide an important means for the creation of new compounds.
    What are the physical properties of 3-Methyl-4-aminopyridine?
    3-Methyl-4-aminopyridine, which is a white to pale yellow crystalline powder. Its melting point is quite high, between 104 ° C and 108 ° C. This property allows it to undergo phase transition under specific temperature conditions.
    When it comes to solubility, it can be dissolved in water and alcohols such as ethanol and methanol. When dissolved in water, it can interact with water molecules through hydrogen bonds to form a uniform solution; in alcohol solvents, it can also achieve good dissolution by virtue of the principle of similar compatibility.
    Looking at its stability, under normal environmental conditions, this substance is relatively stable. However, if exposed to high temperature, open flame or strong oxidant, there is a potential danger. High temperature can cause its molecular structure to change, triggering reactions such as decomposition; open flame is easy to cause it to burn; strong oxidants may undergo violent oxidation reactions with it, changing its chemical composition and properties.
    Furthermore, 3-methyl-4-aminopyridine has a certain alkaline nature. Because the nitrogen atom in the pyridine ring has lone pairs of electrons, it can accept protons, thus exhibiting alkaline characteristics. In the field of organic synthesis, this alkaline property is often used to catalyze some specific reactions, or to participate in the process of acid-base neutralization, thereby realizing the regulation of reaction paths and products.
    3-Methyl-4-aminopyridine chemical synthesis methods
    3-Methyl-4-aminopyridine is also an organic compound. There are many different methods for its synthesis. One common method is to use 3-methylpyridine as the starting material. First, it is nitrified with an appropriate reagent to introduce nitro groups into the pyridine ring. This process requires the selection of suitable reaction conditions, such as temperature, solvent and catalyst, to ensure that the nitro group is introduced to the desired position, that is, the 4-position. After obtaining 3-methyl-4-nitropyridine, the nitro group is converted into an amino group by reduction. There are many reducing agents available, such as hydrogen and suitable catalysts (such as palladium carbon, etc.), under appropriate pressure and temperature for hydrogenation reduction; chemical reducing agents, such as iron and hydrochloric acid systems, can also be used to obtain 3-methyl-4-aminopyridine after reduction reaction.
    There is another method, using pyridine derivatives as starting materials, through multi-step reactions, methyl and amino groups are gradually introduced into the corresponding positions. Or through the reaction of organometallic reagents to accurately construct the molecular structure. For example, using Grignard reagents or lithium reagents, etc., react with pyridine-containing substrates to achieve the introduction and transformation of functional groups, and finally achieve the purpose of synthesizing 3-methyl-4-aminopyridine. However, each method has its advantages and disadvantages, and it needs to be selected according to the actual needs and conditions. When synthesizing, it is necessary to pay attention to the precise control of reaction conditions, the removal of impurities and the purification of the product, in order to obtain high-purity 3-methyl-4-aminopyridine.
    3-Methyl-4-aminopyridine What are the precautions during storage and transportation?
    3-Methyl-4-aminopyridine is an organic compound. During storage and transportation, it is necessary to pay attention to many key matters to ensure safety.
    First storage environment. It should be stored in a cool and ventilated warehouse, away from fire and heat sources, to prevent the temperature from being too high to cause changes in its chemical properties, or even cause danger. The temperature of the warehouse should be controlled within a suitable range, and it must not be too high or too low. Because of its flammability, open flames and hot topics are hidden dangers, so fireworks should be strictly prohibited in the storage place.
    Furthermore, attention should be paid to packaging. Packaging must be sealed and must not be exposed to air to avoid reaction with gases such as oxygen and damage to quality. And the packaging material is also exquisite, it must be resistant to corrosion and pressure, to ensure that it is intact during storage.
    When transporting, extreme caution is also required. During the handling process, it should be handled lightly, and it must not be operated brutally to prevent damage to the packaging. Transportation vehicles should also take protective measures to avoid direct sunlight, and should be equipped with corresponding fire equipment for emergencies. Transportation personnel should also be familiar with the characteristics of this compound and emergency treatment methods. In case of emergencies, they can respond quickly.
    In addition, whether it is storage or transportation, it should be separated from oxidants, acids and other substances. Due to its active chemical properties, contact with these substances can easily cause chemical reactions and lead to accidents. It is also necessary to set up obvious warning signs to remind the surrounding personnel that this is a special chemical and be treated with caution. In this way, the safety and stability of 3-methyl-4-aminopyridine during storage and transportation can be ensured.
    What is the market outlook for 3-Methyl-4-aminopyridine?
    3-Methyl-4-aminopyridine is one of the most valuable in the field of organic compounds. Looking at its market prospects, there are many things to explore.
    In the field of pharmaceutical research and development, it shows unique potential. Many studies are dedicated to finding new drugs, and 3-methyl-4-aminopyridine can be used as a key intermediate due to its special chemical structure. Taking the development of some antibacterial drugs as an example, its structure can be combined with the target of specific bacteria, thus paving the way for the creation of highly effective antibacterial drugs. With the increasing emphasis on health and the increasing demand for new drugs, the potential demand for this compound in the pharmaceutical market is expected to be gradually released.
    In the field of materials science, 3-methyl-4-aminopyridine has also emerged. When preparing some functional polymer materials, it can participate in the polymerization reaction as a reaction monomer. The resulting materials may have unique electrical and optical properties and can be applied to cutting-edge fields such as organic Light Emitting Diodes and sensors. With the rapid development of science and technology, the demand for high-performance materials in electronic devices, sensors and other industries is increasing, which undoubtedly provides a broad market space for 3-methyl-4-aminopyridine.
    However, its market development also faces certain obstacles. On the one hand, the process of synthesizing 3-methyl-4-aminopyridine still needs to be optimized. Some of the current synthesis methods have complicated steps and low yield, which undoubtedly increases production costs and limits large-scale production and application. On the other hand, market awareness also needs to be improved. Although it has shown potential in specific fields, developers of many potential application fields still have a shallow understanding of it, and it needs to be promoted and promoted.
    In summary, the 3-methyl-4-aminopyridine market has a bright future, but it also needs to overcome the problems of synthesis process and marketing activities in order to fully release its market value and occupy an important position in the future technological and industrial development.