3 Methoxypyridine 4 Carbaldehyde
pyridine pyrrole pyrazine piperidine piperazine

3-methoxypyridine-4-carbaldehyde

    Specifications

    HS Code

    760247

    Name 3-methoxypyridine-4-carbaldehyde
    Molecular Formula C7H7NO2
    Molecular Weight 137.14 g/mol
    Cas Number 130302-39-7
    Appearance Solid (usually)
    Boiling Point Approximately 255 - 257 °C
    Melting Point 62 - 64 °C
    Solubility Soluble in organic solvents like ethanol, dichloromethane; slightly soluble in water
    Odor Characteristic aldehyde - like odor

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 3-methoxypyridine-4-carbaldehyde?
    3-Methoxypyridine-4-formaldehyde, an organic compound. Its chemical properties are unique, with the structure of aldehyde group, methoxy group and pyridine ring.
    The aldehyde group has high activity and can participate in many reactions. In oxidation reactions, aldehyde groups are easily oxidized to carboxyl groups. If treated with suitable oxidants, 3-methoxypyridine-4-formaldehyde can be converted into 3-methoxypyridine-4-carboxylic acid.
    In reduction reactions, aldehyde groups can be reduced to hydroxyl groups, which can be converted to 3-methoxypyridine-4-methanol with the help of suitable reducing agents. The
    aldehyde group can also undergo condensation reactions with compounds containing active hydrogen, such as reacting with amine compounds to form imine derivatives. This reaction is often used in organic synthesis to construct nitrogen-containing heterocycles or introduce specific functional groups. The
    methoxy group is attached to the pyridine ring, which has an effect on the electron cloud distribution of the pyridine ring. Methoxy group is the power supply group, which increases the electron cloud density of the pyridine ring, especially in its ortho and para-positions, which in turn affects the electrophilic substitution reaction activity and check point of the compound. Generally speaking, electrophilic substitution reactions are more likely to occur in the ortho and para-positions of methoxy groups on the pyridine ring. < Br >
    The pyridine ring itself is basic, because there are solitary pairs of electrons on the nitrogen atom, which can accept protons. However, compared with aliphatic amines, the pyridine ring is less basic, because the solitary pairs of electrons of the nitrogen atom in the pyridine ring participate in the conjugation system of the ring.
    The chemical properties of 3-methoxypyridine-4-formaldehyde make it widely used in the field of organic synthesis and can be used as an intermediate for the preparation of many organic compounds such as drugs, pesticides and functional materials.
    What are 3-methoxypyridine-4-carbaldehyde synthesis methods?
    The synthesis method of 3-methoxypyridine-4-formaldehyde has been known for a long time, and after many talents have explored, the following commonly used methods have been obtained.
    First, pyridine compounds are used as starting materials. The methoxy group is introduced at a specific position in the pyridine ring first, and this step requires precise selection of reagents and conditions according to its chemical properties. For example, a suitable halogenated pyridine is reacted with a methoxylating agent in an alkaline environment and at a specific temperature, so that the halogen atom is replaced by a methoxy group. Then, another position on the pyridine ring is reacted with an aldehyde group. It is often carried out in a suitable reaction system with a mild oxidizing agent or a specific aldehyde-based reagent in the presence of a suitable catalyst to achieve the purpose of introducing the aldehyde group at the target position, so that 3-methoxypyridine-4-formaldehyde can be obtained.
    Second, start from natural products containing pyridine rings or existing pyridine derivatives. After ingenious chemical modification, the desired structure is gradually constructed. First, the substituent of the starting material is transformed or modified to make it approach the target structure. For example, some groups in the existing pyridine derivatives are oxidized, reduced, and substituted to adjust their structure. After that, methoxy and aldehyde groups are precisely introduced through a series of reactions. This process requires in-depth understanding of the chemical properties of the starting materials, and the reaction conditions of each step need to be carefully controlled in order to effectively synthesize the target product.
    Third, a multi-step reaction strategy is adopted. Using simple organic compounds as starting materials, the pyridine ring is gradually constructed through a multi-step reaction, and methoxy and aldehyde are introduced at the same time. First, a suitable small organic molecule is used to construct the pyridine ring skeleton through condensation, cyclization and other reactions. During or after the construction of the pyridine ring, methoxy and aldehyde are introduced in sequence according to the difference in reaction order and conditions. Although this method has complicated steps, it can flexibly adjust the reaction path, and may have unique advantages for the synthesis of 3-methoxypyridine-4-formaldehyde with specific structures, but it requires high control of reaction operation and conditions.
    3-methoxypyridine-4-carbaldehyde in what areas
    3-Methoxypyridine-4-formaldehyde, which is useful in many fields.
    In the field of medicine, it is often a key synthetic intermediate. The creation of many drugs depends on its participation. Due to its unique chemical structure, it can be combined with other compounds through a series of chemical reactions to create drug molecules with specific pharmacological activities. For example, in the development of targeted drugs for certain diseases, 3-methoxypyridine-4-formaldehyde can be used as a starting material and modified by multiple steps to eventually obtain drugs with precise effects on disease targets.
    In the field of materials science, it also has extraordinary performance. It can be used to prepare organic materials with special properties. For example, in the synthesis of organic optoelectronic materials, it is introduced into the molecular structure of the material, which can adjust the electron cloud distribution of the material, thereby improving the photoelectric properties of the material, such as fluorescence efficiency, charge transport ability, etc. The materials thus prepared may be applied to organic Light Emitting Diode (OLED), solar cells and other devices to improve the performance and efficiency of these devices.
    In the field of fine chemistry, 3-methoxypyridine-4-formaldehyde is an important raw material for the synthesis of a variety of fine chemicals. Like some special fragrances, additives, etc. Because its structure can endow the product with unique properties, it plays an important role in improving the quality and characteristics of the product. In perfume synthesis, it can add unique aroma characteristics to perfume molecules, enriching the types and levels of perfume.
    In addition, 3-methoxypyridine-4-formaldehyde, as a compound with specific functional groups, provides diverse possibilities for the study of organic synthetic chemistry. By exploring various reactions of it, researchers can develop new synthesis methods and routes to promote the development of organic chemistry.
    What is the market price of 3-methoxypyridine-4-carbaldehyde?
    3-Methoxypyridine-4-formaldehyde, the price of this product varies from time to time in the market, and also varies with quality and quantity.
    Looking at the past, the price of chemical materials in the market often depends on the trend of supply and demand, and it is also related to the difficulty of production. If the demand for this product is wide and the output is thin, the price will be expensive; if the output is abundant and the demand is small, the price may be easy.
    Furthermore, its purity is also the main reason for pricing. For high purity, the preparation requires fine technology, so the price is high; for less purity, it is easier to make and the price is slightly lower.
    The amount of quantity also affects the price. If you buy in bulk, the merchant may offer a good price to promote the sale; if you only buy a small amount, the price may not be very discounted.
    At present, although the exact market price cannot be determined, if you want to get the actual price, you can go to the city where the chemical materials are traded, consult the merchant, or visit the online chemical trading platform to get the accurate price in the near future.
    What are 3-methoxypyridine-4-carbaldehyde storage conditions?
    3-Methoxypyridine-4-formaldehyde is an organic compound, and its storage conditions are crucial, which is related to the stability and quality of the substance. When storing this compound, the first dry environment. Because of its aldehyde group, it is easy to react with water and cause deterioration, so it should be stored in a dry place, away from water sources. Desiccants such as anhydrous calcium chloride and molecular sieves can be used to maintain a dry environment.
    Secondly, low temperature storage is required. If the temperature is too high, it can easily cause chemical reactions, causing it to decompose or polymerize. Usually 2-8 ° C is appropriate, such as in the refrigeration layer of the refrigerator.
    Furthermore, light should be avoided. Light can promote photochemical reactions in compounds, affecting their stability. It is recommended to store in brown bottles or opaque containers to isolate light.
    In addition, pay attention to the ventilation of the storage environment. Good ventilation can prevent the accumulation of harmful gases and reduce safety risks, because it may volatilize harmful gases. At the same time, it needs to be stored separately from oxidants, acids, alkalis and other substances. Because of its active chemical properties, it is easy to react in contact with these substances.
    Store 3-methoxypyridine-4-formaldehyde at dry, low temperature, protected from light and well ventilated, and avoid contact with incompatible substances, so as to effectively maintain its quality and stability for subsequent use.