3 Methoxy 6 Trifluoromethyl Pyridine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

3-Methoxy-6-(trifluoromethyl)pyridine-2-carbonitrile

    Specifications

    HS Code

    861331

    Chemical Formula C9H5F3N2O
    Molar Mass 214.144 g/mol
    Appearance Solid (predicted)
    Boiling Point 263.6°C at 760 mmHg (predicted)
    Melting Point 68 - 70 °C
    Density 1.34 g/cm³ (predicted)
    Flash Point 113.2°C (predicted)
    Logp 2.37 (predicted)
    Pka 1.34±0.10 (predicted)
    Solubility Soluble in organic solvents like DMSO, DMF

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    General Information
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    Frequently Asked Questions

    As a leading 3-Methoxy-6-(trifluoromethyl)pyridine-2-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3-Methoxy-6- (trifluoromethyl) pyridine-2-carbonitrile
    3-Methoxy-6- (trifluoromethyl) pyridine-2-formonitrile, this is an organic compound. It has unique chemical properties.
    In terms of reactivity, the cyanyl group is one of the important functional groups of this compound, which has high reactivity. In many chemical reactions, the cyanyl group can participate in the hydrolysis reaction. Under specific conditions, the cyanyl group can be converted into a carboxyl group. In this process, the cyanyl group reacts with water and goes through a series of steps to obtain the corresponding carboxylic acid. For example, under the catalysis of strong acids or bases, the hydrolysis reaction can proceed smoothly. < Br >
    Methoxy is also a key part. Methoxy has a donor electron effect, which affects the electron cloud density distribution of the pyridine ring. This effect changes the electron cloud density at a specific location of the pyridine ring, thereby affecting the activity and selectivity of the electrophilic substitution reaction of the compound. For example, electrophilic reagents tend to attack positions with relatively high electron cloud density.
    And trifluoromethyl, because of its strong electron-absorbing properties, not only affects the electronic structure of the pyridine ring, but also affects the physical properties of the whole molecule. The presence of trifluoromethyl can improve the fat solubility of the compound and affect its solubility in different solvents. In some biological activity studies, compounds containing trifluoromethyl groups often exhibit unique biological activities, or the interaction mode between molecules and biological targets is changed due to the special properties of trifluoromethyl groups.
    The chemical properties of this compound are determined by the interaction of the functional groups it contains, and each functional group affects each other, jointly determining its performance in chemical reactions and practical applications.
    What are the main uses of 3-Methoxy-6- (trifluoromethyl) pyridine-2-carbonitrile
    3-Methoxy-6- (trifluoromethyl) pyridine-2-formonitrile, which has a wide range of uses, is often used as a key intermediate in the field of medicinal chemistry, helping to create special new drugs. The structural differences between Gainpyridine and trifluoromethyl give it unique activities and pharmacological characteristics, and can participate in various reactions to synthesize molecules with specific biological activities, such as anti-cancer, antiviral, and antibacterial drugs.
    In the field of pesticide chemistry, it is also an important raw material. Through chemical transformation, efficient, low-toxic, and environmentally friendly pesticides can be prepared. Its special structure makes pesticides highly selective and active to target organisms, and reduces detoxification and residues, which is suitable for the green development of contemporary agriculture.
    In the field of materials science, it also has a place. Or because it contains nitrogen heterocycles and trifluoromethyl, it can be used to prepare functional materials with special properties, such as organic optoelectronic materials. After rational molecular design and synthesis, such materials may have excellent optoelectronic properties, and can be used in organic Light Emitting Diodes, solar cells, etc.
    Due to its unique structure, this compound has non-negligible uses in many fields such as medicine, pesticides, materials, etc., and contributes to the development of various fields.
    What are the synthesis methods of 3-Methoxy-6- (trifluoromethyl) pyridine-2-carbonitrile
    The synthesis method of 3-methoxy-6- (trifluoromethyl) pyridine-2-formonitrile, through the ages, many wise men have devoted themselves to the field of organic synthesis and have made many gains. The following are common synthetic pathways.
    First, a compound containing a pyridine structure is used as the starting material. Select a pyridine derivative with a modifiable group at a specific position. Introduce the methoxy group before the appropriate check point of the pyridine ring. This step often requires the selection of a suitable methoxylating agent, such as a methylating agent with a specific base. At a suitable temperature and reaction time, the nucleophilic substitution reaction occurs smoothly, and the methoxy group is connected to the pyridine ring. < Br >
    Then, trifluoromethyl is introduced. Trifluoromethyl-containing reagents can be used to successfully connect trifluoromethyl to the target position of the pyridine ring by suitable reaction conditions, such as specific catalysts and solvent systems. Finally, through nitrile reaction, a cyano group is introduced to achieve the synthesis of 3-methoxy-6- (trifluoromethyl) pyridine-2-formonitrile. When nitrile, a suitable nitrile reagent can be selected and operated in a suitable reaction environment.
    Second, it is also a strategy for constructing pyridine rings. Pyridine rings are constructed by multi-step reactions using a variety of nitrogenous and carbon-containing small molecule compounds. First, these small molecules undergo condensation, cyclization and other reactions according to a specific reaction sequence, and initially build a pyridine ring structure. In the process, the reaction steps can be cleverly designed to introduce methoxy, trifluoromethyl and cyanyl groups in an orderly manner at the same time as the pyridine ring formation or in subsequent steps.
    Such various synthesis methods have their own advantages and disadvantages. The craftsman of organic synthesis needs to choose carefully according to the actual situation, such as the availability of raw materials, the difficulty of reaction, and the consideration of cost. The purpose of high-efficiency synthesis of 3-methoxy-6- (trifluoromethyl) pyridine-2-formonitrile can be achieved.
    What is the market outlook for 3-Methoxy-6- (trifluoromethyl) pyridine-2-carbonitrile?
    3-Methoxy-6- (trifluoromethyl) pyridine-2-formonitrile, this is an organic compound. According to the current market prospects, it shows a considerable trend.
    In the field of medicinal chemistry, the development of many new drugs often relies on such specific substituent-containing pyridinitrile compounds. Due to its unique structure, it endows it with diverse biological activities, such as potential antibacterial, anti-inflammatory and anti-tumor activities. With the continuous advancement of medical technology, there is a growing demand for compounds with novel structures and excellent activities. This compound may emerge in the creation of innovative drugs and become a key intermediate for the development of new specific drugs. Therefore, the market demand for it is expected to continue to rise.
    In the field of materials science, organic compounds containing fluorine and methoxy groups often have unique physical and chemical properties, such as good solubility, thermal stability and electrical properties. 3-Methoxy-6- (trifluoromethyl) pyridine-2-formonitrile may be chemically modified and polymerized to prepare high-performance organic electronic materials, such as organic Light Emitting Diode (OLED) materials, solar cell materials, etc. With the rapid development of electronic equipment and new energy industries, the demand for such functional materials will continue to grow, thus opening up a broad market space for this compound.
    However, its market development is not smooth sailing. The process of synthesizing such compounds may involve more complex reaction steps and expensive raw materials, resulting in high production costs, which may limit their large-scale industrial production and wide application to a certain extent. And the marketing activities of new compounds also need to overcome many difficulties, such as drug development needs to go through a long clinical trial stage, material application needs to break through technical bottlenecks and realize industrialization transformation. However, in general, with the progress of science and technology and the development of related industries, 3-methoxy-6- (trifluoromethyl) pyridine-2-formonitrile still has a promising market prospect.
    What are the manufacturers of 3-Methoxy-6- (trifluoromethyl) pyridine-2-carbonitrile?
    I haven't heard of the exact manufacturer of "3 - Methoxy - 6 - (trifluoromethyl) pyridine - 2 - carbonitrile". However, in the field of chemical industry, many manufacturers are involved in the production of fine chemicals and pharmaceutical intermediates.
    This compound may be an important intermediate in the fields of medicine, pesticides, materials, etc. If you want to find its manufacturer, you should explore it in the place of chemical industry clusters. Such as the Yangtze River Delta, the Pearl River Delta, Beijing-Tianjin-Hebei and other developed chemical industries, there are many manufacturers specializing in the synthesis of heterocyclic compounds, and there may be producers of this product.
    Or you can find it on chemical information platforms and industry exhibitions. Chemical information platforms often collect information from many chemical companies, and manufacturers also like to display new products at industry exhibitions. In this place, we may get clues to the manufacturer of "3 - Methoxy - 6 - (trifluoromethyl) pyridine - 2 - carbonitrile".
    However, chemical production is related to safety, environmental protection and many other priorities. Manufacturers of this compound must comply with relevant regulations and standards, and have corresponding technologies and equipment to ensure the safety of the production process and the stability of product quality. To know the exact manufacturer, it is necessary to go deep into the chemical industry, inquire from many parties, and carefully verify before it can be confirmed.