3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

3-Methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxoborocyclopentane-2-yl) pyridine, which is a crucial compound in organic synthesis. Its chemical properties are unique, containing pyridine rings and boronyl ester groups, which are active and show significant activity in many chemical reactions.
In terms of stability, the boronyl ester group is relatively stable under conventional conditions, but it is prone to hydrolysis or other reactions in water or strong acid-base environments. Its stability is also affected by surrounding substituents. The presence of methoxy groups changes the electron cloud distribution of the pyridine ring to a certain extent, which plays a role in the overall stability.
From the reactivity analysis, the nitrogen atom on the pyridine ring has a lone pair of electrons, which can act as an electron donor and react with electrophilic reagents. Boron ester groups can participate in many organic reactions such as the Suzuki coupling reaction, which is an important method for constructing carbon-carbon bonds. In the Suzuki coupling reaction, the boron ester groups of the compound can be coupled with halogenated aromatics or halogenated olefins under the action of palladium catalysts to form new carbon-carbon bonds, resulting in the synthesis of more complex organic molecules.
In addition, methoxy groups, as power supply groups, can affect the electron density and reactivity check point of the pyridine ring. The electron cloud density at specific locations on the pyridine ring is increased due to the electron-donor effect, and electrophilic substitution reactions are more likely to occur at these locations.
The chemical properties of 3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxoboronheterocyclopentane-2-yl) pyridine make it widely used in the field of organic synthesis, providing an important way for the preparation of various organic materials and pharmaceutical intermediates.

The common synthesis methods of 3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine are as follows:
3-methoxy-pyridine can be selected as the starting material. First, 3-methoxy-pyridine is halogenated, usually with a brominating agent such as N-bromosuccinimide (NBS). Under appropriate reaction conditions, such as in an inert solvent (such as carbon tetrachloride), under heating or lighting conditions, bromine atoms are introduced at the 5-position of the pyridine ring to generate 3-methoxy-5-bromopyridine. The key to this step is to control the reaction temperature and the amount of reagents to ensure that the reaction selectively generates the target product.
Then, 3-methoxy-5-bromopyridine is boronized with diphenacol borate. The reaction requires heating and refluxing in an organic solvent (such as 1,4-dioxane) in the presence of a palladium catalyst (such as tetra (triphenylphosphine) palladium (0)) and a base (such as potassium carbonate). The palladium catalyst can effectively promote the reaction, and the base helps to balance the pH of the reaction system and improve the reaction efficiency. In this process, the bromine atom of 3-methoxy-5-bromopyridine is replaced by 4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl to obtain 3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine. After the
reaction, the product needs to be separated and purified. Generally, the organic solvent is removed by vacuum distillation first, and then the column chromatography method is used to separate with a suitable eluent (such as a mixed solvent of petroleum ether and ethyl acetate), and finally the pure target product is obtained. The steps of this synthesis route are relatively simple, the reaction conditions of each step are relatively mild, and the raw materials are easy to obtain, so it is more commonly used in actual synthesis.

3-Methoxy-5- (4, 4, 5, 5-tetramethyl-1, 3, 2-dioxyboron-heterocyclopentane-2-yl) pyridine is useful in many fields such as medicinal chemistry and materials science.
In the field of medicinal chemistry, it is often a key building block for organic synthesis. Through various organic reactions such as Suzuki-Miyaura coupling reaction, it can be linked with halogenated aromatics or halogenated olefins to construct complex pyridine derivatives. Many biologically active drug molecules contain pyridine structures. This compound can be reacted to derive such active molecules to develop new drugs. For example, in the study of anticancer drugs, by modifying their structure, drugs that can target cancer cells may be prepared, which will contribute to the solution of cancer problems.
In the field of materials science, it has also shown its promise. The structure of pyridine ring and boroxacyclopentane gives it unique electronic properties and coordination ability. It can be introduced into polymer materials to improve the photoelectric properties of materials. For example, when used in the preparation of organic Light Emitting Diode (OLED) materials, it can improve the luminous efficiency and stability of the materials, so that the image quality of the display screen is better. Or it can be used in the preparation of sensor materials, with its selective interaction with specific substances, to achieve highly sensitive detection of specific molecules or ions.
In summary, 3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine has broad prospects in the field of medicine and materials, and is a very valuable compound.

I look at the "3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyridine" you inquired about, which is an organic compound. However, its market price is difficult to determine. The price varies due to many factors.
First, the purity of the product is related to the price. If the purity is extremely high, it is almost flawless, and the price will be high; if it contains impurities, the price will drop. Second, the supply channel is also the key. From a regular large factory, the quality is stable, and the price may be high; however, if it comes from a small factory or an informal source, the price may be low, but the quality is unpredictable. Third, the market supply and demand situation determines the price. If there are many people who want it, the supply will be few, and the price will rise; on the contrary, if the supply exceeds the demand, the price will be depressed.
As far as I know, the price of such compounds per gram in the chemical market may range from tens of yuan to hundreds of yuan. However, this is only a rough figure. The actual price must be consulted with the chemical raw material supplier in detail, according to the current market situation and the required quantity. And the chemical market is changing rapidly, and the price fluctuates accordingly, so it is difficult to have constant pricing. Therefore, in order to know the accurate price, real-time inquiry is necessary.

3-Methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine, which is an important compound in the field of organic synthesis. Its storage conditions need to be carefully.
Due to its nature, it should be stored in a dry and cool place. If placed in a humid place, water vapor can easily interact with it, or cause reactions such as hydrolysis, which will damage its structure and purity. And high temperature is also a big taboo. Under high temperature, molecular activity is enhanced, or many side reactions are triggered, causing it to deteriorate.
Furthermore, it needs to be sealed and stored. This is due to the presence of oxygen, carbon dioxide and other gases in the air, or oxidation, addition and other reactions with the compound, which in turn affects its quality. The method of sealing can effectively isolate the air and protect its stability.
In addition, the storage place should be away from fire and heat sources. This compound may be flammable, and in case of open flames or hot topics, there is a risk of combustion and explosion, which endangers safety.
The container for storing this compound should also be careful. It is appropriate to use a container made of glass or specific plastic materials. Because of its relatively stable chemical properties, it is not easy to chemically react with the compound, which can protect its inherent characteristics.
In summary, in order to properly store 3-methoxy-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyridine, it must be cool and dry, sealed and isolated, away from heat, and suitable for containers, so as to protect its quality and prepare for subsequent organic synthesis and other uses.