3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine

3-Isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine is widely used. In the field of medicine, it is often a key intermediate for the creation of new drugs. By ingeniously modifying and modifying its structure, pharmaceutical developers are expected to obtain drugs with specific pharmacological activities and precise responses to various diseases. For example, in the development of anti-tumor drugs, scientists try to use the unique structure of this compound to develop new drugs that can effectively inhibit tumor cell proliferation, induce tumor cell apoptosis, and cause less damage to normal cells.
In the field of pesticides, it also has important functions. Or it can be rationally designed and synthesized to make pesticide active ingredients with high insecticidal, bactericidal or herbicidal properties. Like some new insecticides, molecular design based on them can enhance the interference of the nerve conduction system of specific pests, improve insecticidal efficiency, and reduce the harm to the environment and non-target organisms, which is in line with the current trend of green pesticide development.
In addition, in the field of materials science, this compound may be used as a basic unit for the construction of functional materials due to its own special chemical structure and physical properties. For example, in the study of organic optoelectronic materials, it may participate in the construction of materials with special optical and electrical properties, providing new opportunities for the development of new optoelectronic devices such as organic Light Emitting Diodes and solar cells.

3-Isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine is an organic compound and the like. Its physical properties, the first word appearance, are often white to white powder, fine and uniform, and have a specific texture.
When it comes to the melting point, it is about a specific range. The value of this melting point is the inherent property of the substance. During the heating process, to this temperature range, that is, the solid state gradually melts into the liquid state. The temperature range of this transition can be an important basis for its identification.
Its solubility is also the key physical property. In common organic solvents, such as ethanol and dichloromethane, it shows certain solubility characteristics. In ethanol, the degree of solubility varies with the rise and fall of temperature and the change of solvent ratio. At moderate temperatures and proportions, it can be well dissolved and presents a uniform solution state. This property has a great impact on the reaction operation, separation and purification of organic synthesis. In dichloromethane, due to the polarity and structural characteristics of the solvent, 3-isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine also exhibits corresponding solubility, either partially dissolved or completely soluble, which is related to the interaction of the two.
As for the density, although it is not very easy to intuitively perceive, it is also an important parameter of its physical properties. Under established conditions, it has a specific density value, which is related to its distribution and separation in the mixed system, and has guiding significance for chemical production, experimental operation of material calculation, system construction, etc.
In addition, its stability is also a consideration of physical properties. Under normal environmental conditions, such as room temperature and pressure, general humidity, it can maintain relatively stable structures and properties. However, if the ambient temperature is too high, the humidity is too high, or contact with specific chemical substances, it may also cause changes in physical properties, such as hydrolysis, agglomeration, etc., which in turn affects its performance and quality.

3-Isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine, this is an organic compound. Looking at its chemical properties, this compound has specific physical and chemical properties. In its structure, the core skeleton of pyrazolo [1,5-a] pyridine gives it unique stability and reactivity. The introduction of isobutyryl and isopropyl groups has a great impact on its properties.
In terms of physical properties, its molecular structure contains certain hydrophobic groups, such as isopropyl and isobutyryl, so it is speculated that its solubility in water may be limited, and its solubility in organic solvents such as ethanol and dichloromethane may be better. Its melting point and boiling point are also determined by the intermolecular forces. The complex structure causes a variety of intermolecular forces, and the corresponding melting boiling point may have a specific value.
When it comes to chemical properties, the carbonyl group of isobutyryl is electrophilic and easily reacts with nucleophiles, such as condensation with alcohols to form ester derivatives; or reacts with amines to form amides. Although the 2-position isopropyl group is relatively stable, under certain conditions, such as in a strong oxidizing environment, oxidation reactions may occur. The nitrogen atom on the pyrazolo [1,5-a] pyridine ring is alkaline and can react with acids to form salts, thereby changing its solubility and chemical activity. In addition, the compound may participate in various cyclization and substitution reactions, and has potential application value in the field of organic synthesis. It can be used as an intermediate to construct more complex organic molecular structures through a series of reactions.

The production process of 3-isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine is a key task in the field of fine chemical synthesis. The method is as follows:
The starting material is selected, and when pyrazolo [1,5-a] pyridine is used as the base, this is the core of building the molecular skeleton. To obtain 3-isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine, isobutyryl and isopropyl are introduced precisely.
At the beginning of the reaction, pyrazolo [1,5-a] pyridine and an appropriate halogenated isobutyryl compound, in an alkaline environment, with a suitable organic solvent as the medium, perform nucleophilic substitution reaction. The choice of bases, such as potassium carbonate, sodium carbonate, etc., can enhance the nucleophilicity of pyrazolo [1,5-a] pyridine nitrogen atoms, and then react efficiently with halogenated isobutyryl compounds to form 3-isobutyryl pyrazolo [1,5-a] pyridine intermediates. In this step, the temperature should be controlled in a moderate range, or 50-80 degrees Celsius, and the reaction time should be about several hours to ensure sufficient reaction and few side reactions. < Br >
Next step, the obtained 3-isobutyryl-pyrazolo [1,5-a] pyridine intermediate is reacted with a halogenated isopropyl reagent under similar basic and solvent conditions. In this process, it is crucial to strictly control the reaction conditions, such as reaction temperature, time and reactant ratio. The temperature may be adjusted to 60-90 degrees Celsius, and after several hours of reaction, the isopropyl group can be successfully connected to the molecule, and the final product is 3-isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine.
After the reaction is completed, the product separation and purification are indispensable. It is often done by extraction, column chromatography, etc. During extraction, a suitable organic solvent is selected, and the product is extracted from the reaction system. After column chromatography, a suitable eluent is used to separate the two according to the polarity of the product and the impurity. Purified 3-isobutyryl-2-isopropylpyrazolo [1,5-a] pyridine is obtained.
The entire production process requires strict control of the reaction conditions and fine operation in order to ensure the purity and yield of the product and meet the requirements of industrial production.

I have not heard the exact price of "3 - Isobutyryl - 2 - isopropylpyrazolo [1,5 - a] pyridine" on the market. However, the price range of such compounds is often determined by many factors.
The difficulty of its preparation, if the synthesis steps are complicated and special raw materials or conditions are required, the price will be high. In addition, the availability of raw materials is also important. If raw materials are scarce and difficult to obtain, the price will also be high. Furthermore, the supply and demand situation of the market, the demand exceeds the supply, the price will rise; if the supply exceeds the demand, the price will fall.
In addition, the scale of production also has an impact. Large-scale production, due to the scale effect, the unit cost may drop, and the price may be relatively low; small-scale production, the cost is high, and the price is high. And the purity of the product requires high purity, which is difficult to prepare and expensive.
Although the exact price range is not known, considering the above factors, the price can be deduced or varies greatly due to different situations. In the field of fine chemicals, compounds with special structures and uses may range from tens to thousands of yuan per gram, or even more. The actual price needs to be consulted in detail with chemical raw material suppliers, market survey agencies, or on relevant chemical product trading platforms to obtain a more accurate number.