3-iodo-2-(trifluoromethyl)pyridine

3-Iodine-2 - (trifluoromethyl) pyridine is an important compound in organic chemistry. Its physical properties are crucial and significant for both scientific research and industrial applications.
First of all, its appearance, at room temperature, is mostly colorless to light yellow liquid, and it looks clear and transparent without significant impurities. This appearance characteristic allows researchers to visually judge its purity and state, which is very important for experimental operation and quality control.
times and melting point and boiling point. The melting point is about -30 ° C, and the boiling point is between 190-192 ° C. The low melting point allows it to maintain a liquid state in a relatively mild and low temperature environment, which is convenient for various reaction operations. The value of the boiling point indicates that in order to vaporize it, appropriate temperature conditions need to be applied. These two characteristics are key factors to consider in the separation, purification and reaction conditions of the compound.
Furthermore, the density is about 1.94 g/cm ³. This density characteristic has a significant impact on the process involving liquid-liquid separation or mixing. When participating in the reaction or separation operation with other liquids, the density difference determines its distribution in the system, which in turn affects the reaction process and separation effect.
In terms of solubility, 3-iodine-2- (trifluoromethyl) pyridine is soluble in common organic solvents, such as dichloromethane, chloroform, ether, etc. This solubility facilitates the choice of reaction medium in organic synthesis. By selecting an appropriate solvent, the reaction rate, yield and selectivity can be optimized, and the separation and purification of the product can also be assisted.
In addition, the vapor pressure has corresponding values at specific temperatures. Although the vapor pressure value is not large, the vapor emission under specific reaction environments or storage conditions still needs attention, which is related to experimental safety and compound stability. < Br >
The physical properties of 3-iodine-2 - (trifluoromethyl) pyridine are related to each other and jointly affect its application in many fields such as organic synthesis and drug development. Researchers must consider it carefully before making good use of it.

3-Iodine-2- (trifluoromethyl) pyridine is a crucial chemical substance in the field of organic synthesis. Its use is quite extensive, and it is first applied in the field of medicinal chemistry. In the process of many drug development, this is a key intermediate, which can be cleverly constructed with specific physiological activities through various chemical reactions. For example, in the creation of antimalarial drugs and anti-cancer drugs, it can participate in the formation of pharmacoactive groups with its unique chemical structure, thereby enhancing the affinity and specificity of drugs to targets and enhancing drug efficacy.
Furthermore, in the field of materials science, 3-iodine-2- (trifluoromethyl) pyridine also plays an important role. In the preparation process of new organic optoelectronic materials, the properties of iodine and trifluoromethyl can be used to precisely control the electronic transport properties and optical properties of the materials. By introducing this substance, key parameters such as charge mobility and fluorescence quantum yield can be effectively improved, providing strong support for the development of high-performance organic Light Emitting Diode (OLED), organic solar cells and other materials.
In addition, in the field of pesticide chemistry, this compound also shows unique value. It can be used as an important starting material for the synthesis of new pesticides. After chemical modification, pesticides are given excellent insecticidal, bactericidal or herbicidal activities. Due to the strong electron-absorbing properties of trifluoromethyl in its structure, it can enhance the interaction between pesticide molecules and target enzymes or receptors in organisms, improve the biological activity and environmental stability of pesticides, reduce the dosage of pesticides, and reduce the negative impact on the environment.
In short, 3-iodine-2- (trifluoromethyl) pyridine, with its unique chemical structure, plays an indispensable role in many fields such as drugs, materials, and pesticides, providing key support for promoting technological progress and innovation in related fields.

3-Iodine-2 - (trifluoromethyl) pyridine is an important intermediate in organic synthesis. The common methods for its synthesis have the following numbers.
First, 2 - (trifluoromethyl) pyridine is used as the starting material and prepared by halogenation reaction. Suitable halogenating reagents, such as N-iodosuccinimide (NIS), can be selected. Under appropriate reaction conditions, such as in an organic solvent, control the reaction temperature and time, so that the third position of the pyridine ring is introduced into the iodine atom. The key to this reaction lies in the precise control of the reaction conditions to ensure the selectivity and yield of the reaction. If the temperature is too high, or the side reactions increase; if the temperature is too low, the reaction rate will be delayed.
Second, starting from the pyridine derivatives containing appropriate substituents, the target molecule is constructed through multi-step reaction. For example, the functional groups related to iodine and trifluoromethyl are first introduced, and then the functional group conversion and modification are used to gradually achieve the synthesis of 3-iodine-2- (trifluoromethyl) pyridine. Although this approach is a little complicated, the synthesis strategy can be flexibly adjusted according to different raw materials and reaction conditions to improve the purity and yield of the product. Each step of the reaction requires fine operation, and parameters such as the amount of reaction reagents, reaction time and temperature must be strictly controlled.
Third, the coupling reaction catalyzed by transition metals. If a suitable palladium catalyst is selected, a halogenated pyridine derivative is coupled with a reagent containing trifluoromethyl to introduce trifluoromethyl and iodine atoms at a specific position in the pyridine ring. Such reactions often require optimizing factors such as the type and dosage of catalysts, the selection of ligands, and the type and dosage of bases to obtain the desired reaction effect. Transition metal catalyzed reactions usually have high selectivity and efficiency, but the cost of catalysts and post-treatment of reactions also need to be carefully considered. < Br >
The various methods for synthesizing 3-iodine-2 - (trifluoromethyl) pyridine have their own advantages and disadvantages. It is necessary to choose the appropriate one according to the actual needs and conditions, so as to achieve the synthesis goal of high efficiency, economy and environmental protection.

3-Iodo-2 - (trifluoromethyl) pyridine is an organic compound. When storing and transporting, pay attention to the following things:
First, when storing, the compound should be placed in a cool, dry and well-ventilated place. Because it may be sensitive to air and moisture, it is essential to store it sealed to prevent it from reacting with moisture, oxygen, etc. in the air and causing it to deteriorate. For example, if the storage environment humidity is high, the moisture or reacts with some active parts of the compound, which affects its purity and quality.
Second, temperature control cannot be ignored. Avoid storing in a high temperature environment, which may cause adverse reactions such as decomposition and polymerization of the compound due to high temperature. It is recommended to store it in a specific temperature range, such as the common 0-4 ° C refrigeration conditions, which can effectively extend its shelf life and maintain its chemical stability.
Third, during transportation, ensure that the packaging is firm. The compound may be dangerous, in case of vibration, collision, leakage after package damage, or cause safety problems. Use suitable packaging materials, such as strong glass bottles, wrapped with external buffer materials, and then placed in a solid outer packaging box to reduce the risk of package damage during transportation.
Fourth, due to its chemical properties, transportation and storage should be kept away from fire, heat and strong oxidants. If this compound comes into contact with strong oxidants, it may cause severe oxidation reactions, or even catch fire and explode, threatening the safety of people and the environment.
Fifth, the storage and transportation site should clearly identify the properties, hazardous characteristics, and emergency treatment methods of the compound. In the event of an accident, relevant personnel can quickly take correct measures based on the identification information to reduce losses and hazards.

I think what you are asking is about the market price of 3-iodo-2- (trifluoromethyl) pyridine. However, the price of this product is difficult to say in a single word. The price of this compound often varies due to many factors.
The abundance of its raw materials has a great impact. If the raw materials for preparing this compound are difficult to obtain, the price must vary. When the raw materials are abundant, the preparation cost may be reduced, and the price will follow; if the raw materials are scarce, the cost will be high, and the price will also be high.
The process of preparation is also the key. Sophisticated craftsmanship, or can be efficiently produced, and the product purity is high, so the cost is controllable, and the price is close to the people; if the craftsmanship is complicated, energy consumption is high, and the yield is low, the price is not low.
The supply and demand of the market also affect its price. If the demand is strong, but the supply is insufficient, the price will rise; if the supply exceeds the demand, the merchant will sell the goods, or reduce the price.
In addition, the differences in regions, trade regulations, transportation costs, etc., can all make the price different. In busy commercial ports, the logistics is convenient, or the price is slightly lower; in remote places, the transportation is difficult, and the cost increases, but the price may be higher. < Br >
Therefore, in order to know the exact market price of 3 - iodo - 2 - (trifluoromethyl) pyridine, it is necessary to carefully investigate the raw materials, processes, supply and demand, and pay attention to market changes in real time.