3-IODO-2-METHOXYPYRIDINE 99%

3-Iodine-2-methoxypyridine, with a content of more than 99%, is widely used. In the field of medicinal chemistry, it is an important intermediate in organic synthesis. Using this as a starting material, chemists can use delicate chemical reactions to construct various complex and biologically active compounds, which is of great significance in the development of new drugs, or can help create specific drugs for specific diseases.
In the field of materials science, it also has unique uses. It can be converted into key components of functional materials through specific reactions, endowing materials with unique properties such as special photoelectric properties, and thus applied to cutting-edge materials such as organic Light Emitting Diode (OLED) and solar cells, contributing to the improvement of material properties and technological innovation.
In the fine chemical industry, 3-iodine-2-methoxy pyridine is an important raw material for the synthesis of high-end fine chemicals. Such chemicals are indispensable in the manufacture of fragrances, cosmetic additives, special coatings and many other products, adding unique quality and performance to products to meet the market demand for high-quality fine chemical products.

What you are asking about is the market price of 3-iodine-2-methoxypyridine with a purity of 99%. However, the price of this chemical often varies due to many factors.
First, the trend of supply and demand is the key. If there are many people who want it, but the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price will fall. Second, the difficulty of preparation also affects the price. If the preparation of this product requires complicated processes and high raw materials, the cost will be high and the price will be high. Third, the state of market competition also plays a role. There are many merchants, competing with each other, or lowering prices to compete for the market; if the market is monopolized, the price will be controlled by them.
Furthermore, the purchase quantity is also related to the price. If the batch is large, the merchant may give a discount due to small profits but quick turnover; if the quantity is small, the unit price may be high. In addition, regional differences, transportation fees, tax regulations, etc., can all make the price different.
Therefore, to know the exact price, you should consult chemical raw material suppliers, chemical trading platforms, or observe the market carefully to obtain the accurate number. It cannot be generalized.

The process of preparing 3-iodine-2-methoxypyridine (99% content) probably requires several steps. The first step is to start from a suitable pyridine derivative. 2-methoxypyridine is often used as the raw material, because its structure is similar to the target product, the reaction steps can be reduced and the yield can be improved.
For 2-methoxypyridine, iodine atoms need to be introduced. This step involves electrophilic substitution. First adjust the reaction system to a suitable acidity and temperature, usually in a low temperature environment, such as 0-5 ° C, to control the reaction rate and avoid side reactions. Afterwards, slowly add an iodine source, such as iodine element (I ²), and add an appropriate amount of oxidant, such as hydrogen peroxide (H2O) or periodic acid (HIO). The oxidant can oxidize the iodine element into a more active electrophilic reagent, making it easier to react with 2-methoxy pyridine, and introduce iodine atoms at position 3 of the pyridine ring.
During the reaction process, the reaction process should be closely monitored. Thin-layer chromatography (TLC) is commonly used. A small amount of the reaction solution is regularly taken on a silica gel plate, and it is unfolded with a specific development agent. Observe the spot position and intensity under an ultraviolet lamp to determine the reaction progress.
After the reaction is completed, the product needs to be separated and purified. First, the reaction solution is extracted with a suitable organic solvent, such as dichloromethane, ethyl acetate, etc., and the product is transferred to the organic phase. After that, the organic phase is dried with anhydrous sodium sulfate or magnesium sulfate to remove the moisture. Then the organic solvent is distilled under reduced pressure to obtain the crude product.
The crude product or contains impurities, which needs to be further purified. Ordinary column chromatography, suitable silica gel is selected as the stationary phase, and petroleum ether and ethyl acetate are mixed as the mobile phase in a certain proportion. After the crude product is sampled, it is rinsed with the mobile phase. Due to the different distribution coefficients of impurities and products between the stationary phase and the mobile phase, the separation is achieved, and the final high purity 3-iodine-2-methoxy pyridine can be obtained, and the content can reach 99%

3-Iodine-2-methoxypyridine, with a purity of more than 99%, the Quality Standards are as follows:
The first heavy appearance should be white to off-white crystalline powder, which is an intuitive sign. Its purity is very important, measured by high performance liquid chromatography, the purity needs to reach more than 99%, which is the basis for ensuring its quality.
Melting point is also an important indicator, usually within a specific range, generally about [specific melting point range], if it deviates from this range, the quality is suspicious.
Regarding the impurity limit, a single impurity shall not exceed [X]%, and the total impurity shall not exceed [X]%. This is to control the amount of impurities and ensure the purity of the main component.
Moisture content is also required. Measured by Carl Fischer's method, it should not be higher than [X]%. Excessive moisture will easily cause product deterioration.
Residual solvents, common organic solvents such as methanol, ethanol, etc. must be strictly controlled in accordance with relevant regulations to prevent adverse effects on subsequent use.
Furthermore, the content of heavy metals must also be limited to ensure product safety. The total amount of heavy metals such as lead and mercury shall not exceed [X] ppm.
The above Quality Standards are the key to measuring the quality of 3-iodine-2-methoxypyridine. Any discrepancy in any link may affect its application in medicine, chemical industry and other fields.

3-Iodine-2-methoxypyridine, with a purity of 99%, its storage conditions are quite critical. This compound should be stored in a cool, dry and well-ventilated place. It should be kept away from fires and heat sources, because it may be flammable to a certain extent, and it is easy to cause danger in case of open flames and hot topics.
Furthermore, it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Because substances of different chemical properties come into contact with each other, or cause violent chemical reactions, the quality of the compound will be damaged, and even lead to safety accidents. The storage container must be tightly sealed to prevent it from reacting with moisture, oxygen and other components in the air and causing it to deteriorate.
The storage place should also be equipped with suitable materials to contain leaks. Once a leak occurs, it can be dealt with in time to avoid its spread and cause greater harm. And the stored 3-iodine-2-methoxypyridine should be checked regularly to see if its packaging is in good condition and whether the quality has changed, so as to detect and solve potential problems in time to ensure the safety and stability of its storage process.