3 Hydroxypyridine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

3-hydroxypyridine-2-carbonitrile

    Specifications

    HS Code

    960083

    Name 3 - hydroxypyridine - 2 - carbonitrile
    Molecular Formula C6H4N2O
    Molecular Weight 120.11 g/mol
    Appearance Solid (usually)
    Solubility In Water Limited solubility (predicted due to polar groups and non - polar ring structure)
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka For the phenolic - OH group, around 8 - 10 (estimated)
    Ir Characteristic Peaks CN stretch around 2200 - 2250 cm⁻¹, OH stretch around 3200 - 3600 cm⁻¹, aromatic C - H stretches around 3000 - 3100 cm⁻¹
    Uv Vis Absorption Absorption in the UV region due to aromatic ring and conjugated groups

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    General Information
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    Frequently Asked Questions

    As a leading 3-hydroxypyridine-2-carbonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-hydroxypyridine-2-formonitrile?
    I heard that the three branches of tartary buckwheat are also rare and beautiful. As for flaxseed, it has many functions and is quite important to the world.
    The first use of flaxseed is to nourish human health. Cover flaxseed is rich in unsaturated fatty acids, of which alpha-linolenic acid can be converted into EPA and DHA in the human body. These two are of great benefit to the maintenance of cardiovascular vessels. It can make blood flow smoothly, prevent stagnation, make blood vessels flexible and elastic, so it can lower blood lipids, stabilize blood pressure, and reduce heart diseases. If ordinary people eat flaxseed often, it is like building a dike to prevent floods, which can ensure cardiovascular safety.
    Furthermore, flaxseed also has the function of assisting in gastrointestinal transportation. It contains dietary fiber, which can promote intestinal peristalsis and allow the dross to be excreted smoothly. In this way, it can prevent the suffering of constipation, improve intestinal flora, create a good digestive environment, and make people eat properly without stagnation.
    In addition, flaxseed has the effect of beauty and beauty. Its nutrients can nourish the skin, make the skin moist and radiant, reduce the growth of wrinkles, and delay the aging process of the skin. If a woman wants to keep her youthful color, flaxseed is a good choice.
    Because it is rich in a variety of vitamins and minerals, it can supplement the nutrients needed by the human body, gain the body, and improve the ability to resist diseases. Both young and old can benefit from it. Therefore, flaxseed has extraordinary value in health care and cannot be ignored.
    What are the synthesis methods of 3-hydroxypyridine-2-formonitrile?
    The method of making acetyl has many ends. The ones that can be tested are briefly discussed.
    One is to combine acetic acid with sulfuric acid. Acetic acid is also a synthesizer of acetic acid. Sulfuric acid has a strong corrosive water-borne property. The two are co-placed in a dense vessel, and the heat is applied to add water. Acetic acid meets sulfuric acid, and its chemical properties are excited, and then it starts to react. Sulfuric acid is in the middle of acetic acid, and it is synthesized into sulfuric acid, and acetic acid is produced. Acetic acid is collected in a cooler, and the condensate is condensed. This liquid contains the composition of acetyl. However, the obtained by this method is often mixed with water, and it needs to be refined again before it can be extracted.
    Second, the method of ethanol oxidation. Ethanol is a vulgar alcohol. Take the amount of ethanol and use a specific catalyst, such as acid, etc. Catalysis can promote the reaction speed of the reaction, and the body does not achieve the best synthesis. In the context of aerobic conditions, add ethanol. The ethanol molecule is catalyzed by oxygen and oxygen, and it is reduced to the second time. The alcohol group is oxidized, and the carbonyl group is reduced to acetaldehyde. Acetaldehyde is oxidized in another step to form acetyl. This process requires precise control, high or low temperature, and the amount of black and white matter.
    Third, the ethylene oxidation method. For ethylene, the chemical activity is reduced. Make ethylene oxide, in the presence of a catalyst containing a specific gold, react in an appropriate temperature and force environment. The ethylene molecule is beaten together, and the oxygen atom is combined to form an oxygen compound first, and then a series of reactions such as rearrangement and hydrolysis are formed, which is the most effective way to generate acetyl. This method has a high efficiency and is guaranteed, so the required components are harsh.
    All these methods are used to synthesize acetyl. Each method has its own advantages and disadvantages, and it needs to be based on factors such as the raw materials used, the availability of the desired product, and cost considerations.
    What are the physical properties of 3-hydroxypyridine-2-formonitrile?
    3-Carboxylpyridine-2-formaldehyde, that is, 2-formaldehyde-pyridine-3-carboxylic acid, is a very important raw material and intermediate in organic synthesis. Its physical properties are as follows:
    - ** Properties **: Usually off-white to light yellow crystalline powder. Looking at its shape, it is delicate and uniform, and it shines slightly under light. It is like a fine treasure of precipitation over time, quietly exuding a unique charm.
    - ** Melting point **: about 155-159 ° C. When the temperature gradually rises, this substance is like ice and snow meeting the warm sun, quietly melting from solid to liquid, completing a wonderful transformation of form, just like a gorgeous transformation.
    - ** Solubility **: Soluble in dimethylformamide (DMF), dimethyl sulfoxide (DMSO) and other organic solvents. In DMF, such as salt dissolves in water, it quickly disperses to form a uniform system, showing good compatibility; in DMSO, the same is true, as if they have found a suitable destination, and they are close. Slightly soluble in methanol and ethanol, among the two, the dissolution speed is slightly slower, and the solubility is limited, just like cherishing each other but maintaining a moderate distance. Almost insoluble in water, water and it are like two parallel lines, difficult to blend, and always maintain their own independence.
    - ** Stability **: Under normal environmental conditions, its nature is relatively stable, and it can be like a calm gentleman, sitting in the world, and not easily arguing with its surroundings. However, it is necessary to avoid open flames and hot topics to prevent it from being dangerous like ignited gunpowder. When in contact with strong oxidants, it is also prone to reactions, just like a docile sheep meeting a fierce tiger, which instantly breaks the calm state. When storing, it should be placed in a cool, ventilated and dry place, away from fire and heat sources, and should be stored separately from oxidants. Do not mix storage and transportation, so as to ensure its safety.
    What are the chemical properties of 3-hydroxypyridine-2-formonitrile?
    3-Aminopyridine-2-formaldehyde is an organic compound with unique chemical properties and important uses in many fields.
    As far as its alkalinity is concerned, due to the existence of amino groups, 3-aminopyridine-2-formaldehyde is weakly basic. The nitrogen atom in the amino group has a lone pair of electrons, which can accept protons, and then exhibit alkalinity. However, the electron cloud distribution of the pyridine ring makes the substance less alkaline than aliphatic amines.
    Its nucleophilic reactivity is also worthy of attention. The aldehyde group is an electrophilic group and is vulnerable to attack by nucleophilic reagents. If it reacts with alcohols, it can form acetals; if it reacts with amines, it can form Schiff bases. In this process, the carbon-oxygen double bond of the aldehyde group is opened, and an addition reaction occurs with the nucleophilic reagent.
    Furthermore, the amino group in 3-aminopyridine-2-formaldehyde can participate in many reactions. For example, acylation can be carried out, which interacts with acyl halides or acid anhydrides, and the hydrogen atom of the amino group is replaced by the acyl group to form the corresponding amide derivative. This reaction is often used in organic synthesis to construct compounds containing amide bonds.
    In addition, the properties of the pyridine ring also affect the chemical behavior of the substance. The pyridine ring has certain aromatic properties and stability, and the electron cloud distribution on the ring is uneven, which causes it to undergo electrophilic substitution reactions. However, due to the localization effect of amino groups and aldehyde groups, the check point of electrophilic substitution reaction is different from that of ordinary pyridine. Usually, amino groups are ortho-para-localizers and aldehyde groups are meta-localizers. Under the combined action, the check point selectivity of the reaction presents a specific law.
    In the field of organic synthesis, 3-aminopyridine-2-formaldehyde is often used as a key intermediate in the synthesis of various complex organic compounds, and plays an important role in pharmaceutical chemistry, materials science, etc.
    What is the price range of 3-hydroxypyridine-2-formonitrile in the market?
    In today's world, business conditions are unpredictable, and market prices are also unpredictable. However, if you want to know the price range of B vegetables in the market, I should try my best to explain it.
    Looking at the recent market situation, the price of B vegetables often varies according to the season, origin, supply and demand. When it is in its prime, the fields are full of fruits and vegetables, and there are many vendors, but the price is flat. In normal seasons, the price may be between a few and more than ten texts per catty.
    If the weather is not smooth, or the drought and waterlogging pests cause the output to drop sharply, and the needs of the people in the city are not reduced, the price will rise. At this time, the price per catty may reach twenty or even higher, and it is unknown.
    And if the place of origin is different from near and far, if it is transported from a long way, the fare will increase, and the price will be higher than that of local production. Locally produced B vegetables may be slightly cheaper, but it also depends on the amount of harvest in the season.
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    To sum up, the price of B vegetables in the city can range from a few to one catty, and as many as more than 20 to one catty. It is difficult to determine an exact number. It varies with various factors.