3-Hydroxy-2-n-propylpyridine-4,5-dicarboxylicacid

3-Hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid, an organic compound. It has a wide range of uses and can be used as a key intermediate in the field of medicinal chemistry to create drug molecules with specific biological activities. Due to its unique chemical structure, it can interact with specific targets in organisms, thus exhibiting various biological activities such as antibacterial, anti-inflammatory, and anti-tumor, providing a broad space for the development of new drugs.
In the field of materials science, it may participate in the synthesis of polymer materials. By polymerizing with other monomers, it imparts special properties to materials, such as improving their solubility, thermal stability, and mechanical properties. And because there are multiple active checking points in the molecule, it can introduce functional groups into materials and expand the application range of materials, such as optical materials, electronic materials and other fields.
In the field of chemical research, as an important block of organic synthesis, chemists can prepare compounds with diverse structures by structural modification and derivatization reactions, and then deeply explore the mechanism of organic reactions and expand the methodology of organic synthesis. It also has important applications in coordination chemistry. It can use coordination atoms such as carboxyl and hydroxyl groups to coordinate with metal ions to construct metal-organic complexes with unique structures and properties, showing potential application value in catalysis, gas adsorption and separation.

3-Hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid, this substance has specific properties and is of great value for investigation.
Looking at its physical properties, it may be a solid state at room temperature, but it also varies slightly due to changes in temperature and humidity around it. Its color is mostly white to off-white, just like the purity of early winter snow, or yellowish, just like the light light of morning light. Its texture is delicate, like a delicate powder, and it seems to be smooth when touched lightly.
Solubility is also its important physical property. In water, its degree of solubility is limited, just like a leaf boat floating on the surface of a vast river, it can only hold a little. However, in polar organic solvents, such as ethanol and acetone, their solubility is significantly improved, such as ice entering warm water and gradually melting into it. This property is closely related to the molecular structure. The polar groups such as hydroxyl and carboxyl groups contained in it interact with the polar solvent molecules to cause the change of dissolution.
The melting point is also a key physical property. After rigorous determination, its melting point is roughly within a specific range. This value is like a ruler, which can measure its purity and quality. When the temperature gradually rises to the melting point, this material melts like ice and snow, and quietly melts from a solid state to a liquid state. This process also reflects the change of its intermolecular forces.
Furthermore, its stability is also worthy of careful investigation. In the general environment, if there is no extreme conditions such as strong acid and alkali interference, it can still maintain a relatively stable state. In case of high temperature, high humidity, or specific chemical reagents, their structure or changes, just like a fragile flower in the wind and rain, and their physical properties also change accordingly.
The physical properties of 3-hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid are of great significance in many fields such as chemistry and medicine. Only by knowing its properties can we make good use of it and give full play to its maximum value.

To prepare 3-hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid, the method is as follows:
Take the first pyridine derivative as the starting material, which may be a pyridine compound with modifiable groups, so as to facilitate the subsequent reaction to introduce the desired functional group.
In a suitable reaction vessel, dissolve it in a suitable organic solvent, which should have good solubility to the reactants and be compatible with the reaction conditions, such as dichloromethane, N, N-dimethylformamide, etc.
Next, add a specific reagent to introduce n-propyl. The method of nucleophilic substitution can be selected, and the reagent containing n-propyl group, such as n-propyl halide, can react in the presence of alkali. The base can promote the formation of nucleophilic reagents, such as potassium carbonate, sodium hydride, etc., and control the temperature and stir it to make the reaction uniform and sufficient. The temperature is adjusted according to the activity of the reagent and the reaction process, or between room temperature and moderate heating, and may need to be refluxed.
After the n-propyl group is connected, turn to the hydroxyl group. 3-hydroxyl groups are often obtained by oxidation or substitution. If oxidation is used, the oxidizing agent, such as hydrogen peroxide, m-chloroperoxybenzoic acid, etc., is selected, and the dosage is determined according to the activity of the
As for the construction of 4,5-dicarboxylic acids, or by carboxylation reaction. Activate the pyridine ring with a metal reagent, such as butyl lithium, and then react with carbon dioxide to connect the carboxyl group to the 4,5 position. After the reaction, after post-treatment, such as extraction, washing, column chromatography or recrystallization, the product is purified to obtain 3-hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid. Each step of the reaction needs to be carefully controlled and adjusted according to the product monitoring to achieve good yield and purity.

I don't know the price range of 3 - Hydroxy - 2 - n - propylpyridine - 4,5 - dicarboxylic acid on the market. This is a relatively uncommon chemical substance, and its price often varies depending on many factors. For example, the purity is high, the price is high if the purity is high; the difficulty of preparation, if the preparation process is complicated and the cost is high, the price is also high; if the supply and demand relationship exceeds the demand, the price will fall, and if the supply exceeds the demand, the price will rise. And different suppliers, purchase quantities, market regions, etc. all have an impact on the price. To know the exact price range, you need to consult chemical product suppliers, chemical raw material trading platforms or relevant industry insiders in detail to obtain accurate information.

3-Hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid, this is an organic compound. Its stability is related to many elements, let me talk about them one by one.
First, the chemical structure affects the stability. The compound contains a pyridine ring, which has a certain aromaticity, giving it a certain structural stability. However, the hydroxyl, n-propyl and dicarboxylic acid groups attached to the ring have different effects on its stability. Hydroxyl groups have active hydrogen atoms, which easily participate in hydrogen bond formation and chemical reactions, such as oxidation reactions, or neutralization with bases, which affect the stability. N-propyl is an alkyl group, which has the electron supply effect and affects the electron cloud distribution of the pyridine ring, which can change its chemical activity and stability to a certain extent. The dicarboxylic acid group is highly acidic and easy to dissociate under different pH environments, which affects the overall stability of the compound.
Let's talk about external environmental factors. When the temperature rises, the thermal motion of the molecule intensifies, which prompts the chemical reaction rate to accelerate, or causes the compound to decompose, rearrange and other reactions, and the stability decreases. When exposed to light, if the compound absorbs light of a specific wavelength, the light energy can initiate photochemical reactions, destroy its chemical bonds, and reduce its stability. In a strong acid or alkali environment, the acidic or basic groups contained in it will react with the acid and base to change the molecular structure and cause stability changes. Under basic conditions, dicarboxylic acid groups are prone to form salts, while under acidic conditions, hydroxyl groups may be protonated, which affects their stability.
In organic solvents, the solvent interacts with the molecule of the compound or affects its stability. Polar solvents interact with the polar group of the compound or change its molecular conformation, which in turn affects its stability.
In summary, the stability of 3-hydroxy-2-n-propylpyridine-4,5-dicarboxylic acid is influenced by its own chemical structure and external temperature, light, pH, solvent and other factors. To accurately grasp its stability, various factors need to be comprehensively considered.